Gene Information

Name : Bcer98_3326 (Bcer98_3326)
Accession : YP_001376538.1
Strain : Bacillus cytotoxicus NVH 391-98
Genome accession: NC_009674
Putative virulence/resistance : Resistance
Product : methionine gamma-lyase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 4.4.1.1
Position : 3396596 - 3397786 bp
Length : 1191 bp
Strand : -
Note : catalyzes the formation of methanethiol and 2-ocobutanoate from L-methionine

DNA sequence :
ATGAAAAAGAGCAATATGGAGACAGATTTCATTCATTATGGATATGAACCAGGTGTACATAAAGGAAGCTTAACGCCACC
TTTATTTCAAACTTCAACTTATACATTTGAAACAGCGAAACAAGGGGAAGATAGTTTTACTGGGCAAGATTCATCCTATA
TTTACTCACGGCTTGGTAATCCGACTGTAGAGTTATTTGAAGAACGCATGGCAGCTTTAGAAGGGGGAGAAGTTGCATTA
GCGTTTGGATCGGGTATGGCTTCTATTTCGGCGACATTGCTTGCTTGTTTACGTGCAGGGGATCATATGATTTGTTCCAA
TGGCTTATACGGTTGTACGTACGGTTTTTTGGAAGTGTTAGAGGAAAAATTTATGATTTCACATTCATTTTGTGATATGG
AAACGGATGAGCAGATTGAGAAAGAAATTCTTCCGAATACGAAGTTGATTTTCGTTGAAACACCTATTAATCCAACAATG
AAACTGATTGATTTAGAAAAAGTGATTAAAGTAGCAAAGAAAAATCATTTACTTGTTATTGTTGATAATACATTTTGTTC
TCCATACTTACAAAATCCACTTGTTCTTGGGTGTGATGCGGTTCTTCATAGCGCAACGAAATATATTGGGGGACATGGTG
ATGTAGTTGCGGGAGTTACTGTTTGTAAAACGAGGGAGTTAGCCGAAAAAATCCGTCCGATTCGAAAAGATATTGGGGGA
ATTATGGCGCCTTTTGATGCATGGTTATTATTAAGAGGGCTAAAAACGTTAGCTGTTCGAATGGATCGACATTGTGATAA
TGCGGAGAAGGTAGTAGCTTTTTTGAAAAATCATGAAAAGGTTGAAAAGGTTTGGTATCCAGAAGGAGAACGAGCATCTC
GGCAAATGAAGCGTGGTGGGGGTGTTATTTCGTTCTCTATTAAAGGAGGAAAAGAAGAAGCACAAGCTTTTATGGACAAA
TTAAATTTGATTGCGATTGCGGTCAGTCTTGGTGATACAGAAACATTAGTACAGCATCCCGCGACAATGACACATGCGGT
CATTCCAGCAGAAGTTCGTCAGAAAATGGAGATTTTTGATAATTTAATTCGTTTATCTGTCGGTTTAGAATCATGGGAAG
ATATTATTTCTGATTTACAGCAGGCGTTAAATAGCAGCAACGTTATATCCTCTAGCATACATTATAAATAA

Protein sequence :
MKKSNMETDFIHYGYEPGVHKGSLTPPLFQTSTYTFETAKQGEDSFTGQDSSYIYSRLGNPTVELFEERMAALEGGEVAL
AFGSGMASISATLLACLRAGDHMICSNGLYGCTYGFLEVLEEKFMISHSFCDMETDEQIEKEILPNTKLIFVETPINPTM
KLIDLEKVIKVAKKNHLLVIVDNTFCSPYLQNPLVLGCDAVLHSATKYIGGHGDVVAGVTVCKTRELAEKIRPIRKDIGG
IMAPFDAWLLLRGLKTLAVRMDRHCDNAEKVVAFLKNHEKVEKVWYPEGERASRQMKRGGGVISFSIKGGKEEAQAFMDK
LNLIAIAVSLGDTETLVQHPATMTHAVIPAEVRQKMEIFDNLIRLSVGLESWEDIISDLQQALNSSNVISSSIHYK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 7e-60 41
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 4e-61 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Bcer98_3326 YP_001376538.1 methionine gamma-lyase BAC0207 Protein 1e-86 46