Gene Information

Name : hemC (Bcer98_3180)
Accession : YP_001376398.1
Strain : Bacillus cytotoxicus NVH 391-98
Genome accession: NC_009674
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 3231644 - 3232573 bp
Length : 930 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGCGCAAAATTATTGTAGGTTCAAGAAAGAGTAAGCTGGCATTAACGCAAACGAATTGGTTTATTGATCAATTACAAGC
GCTTGGCTTACCGTATGAATTTGAAGTAAAGGAAATTGTTACAAAAGGGGATGTCATTTTAGACGTTACGCTTTCTAAAG
TAGGCGGTAAAGGGTTGTTTGTAAAAGAGATTGAGCATGCTCTTCTTACAAAAGAAATCGATATGGCTGTACACAGTATG
AAAGATATGCCTGCTGTGCTCCCAGCTGGTTTAACAATTGGGTGTATACCAAAGCGTGTGGATCCGCGTGATGCATTTAT
TTCAAAGAATGGGAAATCGTTTAAGGAGTTAGCAAAGGGTGCAACTCTTGGTACGAGCAGTTTAAGACGTAGCGCACAAT
TATTAGCTGCTAGACCTGACTTACAAGTGAAATGGATTCGTGGAAATATCGATACGAGATTACGTAAATTACAAGAAGAA
AACTATGATGCAATTATTTTAGCAACAGCTGGACTAAAGCGGATGGGTTGGGATAATGATGTAATTACAGAACATCTGGA
CGAATCTTTATGTGTACCAGCTGTAGGACAAGGTGCTTTAGCTATTGAATGTCGTGAAGATGATAAGGACTTATTACAGT
TATTAGCACATATGAACGATGCAGCAACAGAACGAACAGTAGCGGCAGAAAGAGTGTTTCTTCATAAGCTTGAAGGAGGA
TGTCAAGTACCTATTGCAGGATATGCAACCCTTCAAGAAAATGGAAAAATTAAATTACATGCACTTGTTGGATCAACGGA
TGGCTCTGTCTTATTAAAAGAAACAGTAGTAGGTACAAATCCCGAGACAGTAGGGTTAGAGGCGGCAGAGCGCTTGATTC
ATCAAGGTGCAAAAGAGCTCATTTCAGCTGCAAATAAGGAGCAACAATAA

Protein sequence :
MRKIIVGSRKSKLALTQTNWFIDQLQALGLPYEFEVKEIVTKGDVILDVTLSKVGGKGLFVKEIEHALLTKEIDMAVHSM
KDMPAVLPAGLTIGCIPKRVDPRDAFISKNGKSFKELAKGATLGTSSLRRSAQLLAARPDLQVKWIRGNIDTRLRKLQEE
NYDAIILATAGLKRMGWDNDVITEHLDESLCVPAVGQGALAIECREDDKDLLQLLAHMNDAATERTVAAERVFLHKLEGG
CQVPIAGYATLQENGKIKLHALVGSTDGSVLLKETVVGTNPETVGLEAAERLIHQGAKELISAANKEQQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 2e-61 50
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 2e-61 50