Gene Information

Name : guaA (Bcer98_0253)
Accession : YP_001373614.1
Strain : Bacillus cytotoxicus NVH 391-98
Genome accession: NC_009674
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 271338 - 272876 bp
Length : 1539 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
TTGAAAAAACAGCACGATACGATTATCGTTTTAGACTTTGGAAGTCAGTACAACCAATTAATTGCACGTCGCATTCGTGA
GTTCGGTGTGTACAGTGAGCTTCATCCACACACAATTACTGCGGAAGAAATTAAAGCAATGAATCCAAAAGGTATCATTT
TCTCTGGTGGACCAAATAGTGTATACGGCGAAAATGCATTCCACTGTGATGAGAAAATTTTTGAGCTAGGATTACCTATT
TTTGGTATTTGTTACGGCATGCAGCTGATGACAAAACACTTTGGTGGAAAAGTAGAGCGAGCAAACCATCGTGAGTACGG
AAAAGCAGTTCTGAAAGTAGAGAATGAATCAAAATTATATACAAACCTGCCAGAAGAACAAGTTGTATGGATGAGCCATG
GTGACTTAGTAACAGGTTTACCAGAAGGCTTTGTAGTAGATGCAACGAGCGAATCTTGTCCAATTGCTGGTATGAGCAAT
GAAGAAAAGCAGTTATACGGTGTACAATTCCATCCAGAAGTACGTCACTCTGAGCACGGTAATGATTTAATTAAAAACTT
CGTATTCGGCGTATGCGGTTGTTCTGAAGGCTGGAACATGGAGAACTTTATTGAAGTAGAATTAGAAAAAATTCGTGAAA
CAGTTGGTGATAAAAAAGTACTATGTGCACTTAGCGGTGGTGTAGATTCTTCTGTTGTAGCTGTATTAATTCATAAAGCA
ATCGGTGATCAGTTAACATGTATTTTTGTTGACCACGGTTTACTTCGTAAAGGTGAAGCAGAAGGTGTTATGAAAACATT
TAGCGAAGGCTTCCATATGAATGTTATTAAAATCGATGCTAGAGAACGCTTCATGAAAAAGCTAAAAGGTGTAGAAGATC
CTGAACAAAAACGTAAAATTATCGGTAACGAATTCATTTATGTTTTTGATGATGAAGCTGCTAAATTAGAAGGAATAGAC
TTCTTAGCGCAAGGTACACTGTACACAGACATTATTGAAAGTGGTACAGCAACTGCGCAAACAATTAAATCTCACCATAA
CGTAGGTGGACTTCCAGAAGATATGCAGTTCAAATTAATCGAGCCTTTAAATACGTTATTTAAAGATGAAGTACGTGTAT
TAGGATCAGAACTAGGAATTCCTGATGAAATTGTATGGCGTCAACCATTCCCAGGTCCTGGACTTGGTATTCGTGTATTA
GGTGAAATTACAGAAGAAAAATTAGAAATTGTTCGTGAATCTGATGCGATTTTACGTGAGGAAATCCAAAAAGCAGGATT
AGACCGTGAAATTTGGCAATACTTCACTGCGCTTCCTGGTATGCGCAGCGTAGGTGTTATGGGTGACGAGCGTACTTACG
ATTATACAGTAGGTATCCGTGCCGTAACATCAATTGACGGTATGACAGCTGACTGGGCACGTATCCCTTGGGACGTATTA
GAGAAAATCTCTGTACGTATCGTAAACGAAGTAAAACACGTGAACCGCGTTGTATATGATATTACTTCTAAGCCACCAGC
AACGATTGAGTGGGAATAA

Protein sequence :
MKKQHDTIIVLDFGSQYNQLIARRIREFGVYSELHPHTITAEEIKAMNPKGIIFSGGPNSVYGENAFHCDEKIFELGLPI
FGICYGMQLMTKHFGGKVERANHREYGKAVLKVENESKLYTNLPEEQVVWMSHGDLVTGLPEGFVVDATSESCPIAGMSN
EEKQLYGVQFHPEVRHSEHGNDLIKNFVFGVCGCSEGWNMENFIEVELEKIRETVGDKKVLCALSGGVDSSVVAVLIHKA
IGDQLTCIFVDHGLLRKGEAEGVMKTFSEGFHMNVIKIDARERFMKKLKGVEDPEQKRKIIGNEFIYVFDDEAAKLEGID
FLAQGTLYTDIIESGTATAQTIKSHHNVGGLPEDMQFKLIEPLNTLFKDEVRVLGSELGIPDEIVWRQPFPGPGLGIRVL
GEITEEKLEIVRESDAILREEIQKAGLDREIWQYFTALPGMRSVGVMGDERTYDYTVGIRAVTSIDGMTADWARIPWDVL
EKISVRIVNEVKHVNRVVYDITSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 0.0 74
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 0.0 74
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 0.0 74
guaA NP_938969.1 GMP synthase Not tested Not named Protein 3e-139 54