Gene Information

Name : Bcer98_1756 (Bcer98_1756)
Accession : YP_001375051.1
Strain : Bacillus cytotoxicus NVH 391-98
Genome accession: NC_009674
Putative virulence/resistance : Virulence
Product : 2,3-dihydroxybenzoate-AMP ligase
Function : -
COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism
COG ID : COG1021
EC number : -
Position : 1866145 - 1867767 bp
Length : 1623 bp
Strand : +
Note : TIGRFAM: 2,3-dihydroxybenzoate-AMP ligase; PFAM: AMP-dependent synthetase and ligase; KEGG: bca:BCE_2400 2,3-dihydroxybenzoate-AMP ligase

DNA sequence : 
ATGATGTTATCAGGATGTTATGAATGGCCTAAAGAATTTGCAAATCGGTACAGAGAAGCCGGTTGTTGGCGCGGAGAAAC
GTTTGGAGAAATGCTCAGAGAACGGGCTATCAAGTATGGTGAACGCATTGCATTGACGAGCGGGGAACATCATATAAGTT
ATAAAGAATTTGATAAACGAGTGGATCGTTTAGCCGCTGGTTTTCTATCGCTAGGGATTAAAAAAACAGATCGTGTCGTT
CTTCAGTTACCCAATATTATAGAGTTTTTTGAAGTGTGTTTTGCACTTTTTCGAATTGGGGCTCTTCCGGTGTTCGCTCT
GCCAGCACATCGAAGTAGCGAGATTTGTTATTTTTGTGAATTTGCTGAAGCTACTGCTTATATTATTGCAGATAAACAAC
TTGGATTTGACTATCGAAATCTTGCAAGAGACGTGAAAAGAAAAGTACCGACATTGAAGCATATCATTGTTGTTGGTGAG
GAAGAAGAGTTTGTTGGAATTCATGATTTATATAGAGAACCAGTTGACTTACCTGAAGTGAAATCTAGCGATGTAGCTTT
CTTACAACTATCAGGAGGGACAACAGGACTACCGAAACTCATTCCAAGAACACACGATGACTATATTTATAGTTTACGAG
TAAGCGCTGAGATTTGTCGATTGAATGAGGATAGTGTATATCTCGTTGTTCTTCCGGTTGCTCATAATTACCCGCTCAGC
TCACCAGGAACTCTCGGAACATTTTATGCTGGGGGAAGGGTTGTGCTCGCTTCTGGAGGGAGTCCCGATGAAGCGTTTGC
TTTAATTGAGAAGGAACGCGTCACAATTACAGCGCTTGTACCGCCGCTTGCGATGATATGGCTGGATGCAAAAGCATCGC
GCCATAATGATTTATCTAGCCTTCAAGTTTTGCAAGTTGGAGGTGCAAAGTTTAGCGCAGAAGCTGCGAAACGTATACGT
CCTACATTTGGGTGTACATTGCAACAAGTATTTGGCATGGCAGAAGGGTTAGTCAATTATACAAGACTTGATGATTCTGA
AGAAATGATTATTCATACGCAAGGGCGACCTATGTCAGAGTTTGATGAAGTACGTGTCGTAGATGAAAATGACTGTGACG
TAAAGACGGGTGAAGTGGGAAGGCTATTAACTCGTGGTCCCTATACGATTCGCGGTTATTATAAAGCGGAAGAACATAAT
GCGAAATCTTTTACACCTGATGGTTTTTATCGTACAGGTGATCTCGTGAAAATAAATGAGAACGGGTATTTAGTCGTCGA
AGGTCGCGATAAAGATCAAATTAATCGCGGAGGGGAAAAAGTAGCAGCAGAAGAGGTAGAAAATCATCTGTTAGCCCACC
ATTCCGTTCATGATGCTGCAATTGTATCAATGCCTGATGAGTATTTAGGAGAACGTACTTGTGCTTTCATCATCGCGCGC
GGACAACAGCCATCCGTAGGAGAGCTAAAAACATTTTTAAGAGAACGCGGAATTGCGGCGTATAAAATTCCGGATCGAAT
TGAATTTGTTAAAGCGTTTCCGCAAACTGGTGTAGGGAAAGTAAGTAAGAAAGACTTACGAAAAGCAATTGCTGAAAGAT
TACAGTCTACCATTCATTCATAA

Protein sequence : 
MMLSGCYEWPKEFANRYREAGCWRGETFGEMLRERAIKYGERIALTSGEHHISYKEFDKRVDRLAAGFLSLGIKKTDRVV
LQLPNIIEFFEVCFALFRIGALPVFALPAHRSSEICYFCEFAEATAYIIADKQLGFDYRNLARDVKRKVPTLKHIIVVGE
EEEFVGIHDLYREPVDLPEVKSSDVAFLQLSGGTTGLPKLIPRTHDDYIYSLRVSAEICRLNEDSVYLVVLPVAHNYPLS
SPGTLGTFYAGGRVVLASGGSPDEAFALIEKERVTITALVPPLAMIWLDAKASRHNDLSSLQVLQVGGAKFSAEAAKRIR
PTFGCTLQQVFGMAEGLVNYTRLDDSEEMIIHTQGRPMSEFDEVRVVDENDCDVKTGEVGRLLTRGPYTIRGYYKAEEHN
AKSFTPDGFYRTGDLVKINENGYLVVEGRDKDQINRGGEKVAAEEVENHLLAHHSVHDAAIVSMPDEYLGERTCAFIIAR
GQQPSVGELKTFLRERGIAAYKIPDRIEFVKAFPQTGVGKVSKKDLRKAIAERLQSTIHS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 1e-116 49
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 1e-116 49
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 8e-117 49
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 2e-116 49
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 1e-116 49
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 1e-116 49
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 1e-116 49
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 1e-116 49
ybtE CAA21394.1 - Virulence HPI Protein 1e-116 49

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Bcer98_1756 YP_001375051.1 2,3-dihydroxybenzoate-AMP ligase VFG0168 Protein 1e-141 56
Bcer98_1756 YP_001375051.1 2,3-dihydroxybenzoate-AMP ligase VFG0932 Protein 5e-114 48
Bcer98_1756 YP_001375051.1 2,3-dihydroxybenzoate-AMP ligase VFG1817 Protein 2e-109 46