Gene Information

Name : thyA (Bcer98_1639)
Accession : YP_001374943.1
Strain : Bacillus cytotoxicus NVH 391-98
Genome accession: NC_009674
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : 2.1.1.45
Position : 1744142 - 1745098 bp
Length : 957 bp
Strand : +
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGAAACATGCTGAATATGAATATTTAAATTTATGCCGCCATGTCATGGAGCATGGTACAAAGAAAGAAGATCGTACAGG
AACAGGGACGGTATCTGTATTTGGATATCAAATGCGCTTTGACCTTAGTAAAGGGTTTCCCTTATTAACGACAAAGCGAG
TGCCATTTCGTCTTGTTGCAAGTGAGTTACTTTGGTTTATGAAAGGTGATACCAATATTCGTTATTTATTGCAACATAAT
AATAATATTTGGAATGAATGGGCGTTTAAAAACTGGGTAGAAAGTGATGAATATAAAGGGCCGGACATGACGAATTTCGG
ACTGCGCTCACAAGAAGATGAAGCATTTAAAACACAATACGATGAGCAAATGGAAATCTTTAAAAAGAATGTATTAGAAG
ATGATGAATTTGCGCGGAAGTATGGTTATTTAGGAGATGTATATGGCAAGCAGTGGCGCGCTTGGAAAACGGCTGCAGGT
GAAACGATTGATCAATTAAAAGATGTAATTGAAATGATTAAGAAAACACCGGATTCTCGCCGCTTAATTGTTTCGGCATG
GAATCCTGAAGATGTACCAAATATGGCACTTCCTCCATGCCATACATTATTCCAATTTTATGTAGCAGATGGAAAGCTTT
CTTGTCAATTATATCAACGAAGTGGAGATATTTTCTTAGGTATTCCATTTAATATTGCAAGCTATTCGCTGTTAACGCAT
TTAATTGCTCATGAGTGTGGCCTTGCAGTAGGAGAGTTTGTTCATACAATTGGCGATGCACATATTTACACAAATCATTT
TGAACAAGTGAAGAAGCAATTAGCACGTGAACCACGTCCATTTCCAACATTAAAATTAAATTCAGATGTGAAATCTGTTT
TTGATTTTGAAATGGGTGATTTAACAATAGAAGGATATGACCCGCATCCAGCAATTAAAGCACCAGTTGCAGTCTGA

Protein sequence :
MKHAEYEYLNLCRHVMEHGTKKEDRTGTGTVSVFGYQMRFDLSKGFPLLTTKRVPFRLVASELLWFMKGDTNIRYLLQHN
NNIWNEWAFKNWVESDEYKGPDMTNFGLRSQEDEAFKTQYDEQMEIFKKNVLEDDEFARKYGYLGDVYGKQWRAWKTAAG
ETIDQLKDVIEMIKKTPDSRRLIVSAWNPEDVPNMALPPCHTLFQFYVADGKLSCQLYQRSGDIFLGIPFNIASYSLLTH
LIAHECGLAVGEFVHTIGDAHIYTNHFEQVKKQLAREPRPFPTLKLNSDVKSVFDFEMGDLTIEGYDPHPAIKAPVAV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_189147.1 thymidylate synthase Not tested ¥ÕSP¥â Protein 3e-105 65