Gene Information

Name : guaA (Oant_3058)
Accession : YP_001371595.1
Strain :
Genome accession: NC_009668
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 368655 - 370226 bp
Length : 1572 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGCTGCACATGAGCACCACGGCACATCCCGACACAATCCTAATCATCGACTTTGGCAGCCAGGTTACGCAGCTGATTGC
GCGTCGCGTGCGCGAAGCCAACGTCTATTGTGAAATCGTCCCTTTCCAGTCTGCGGAAGAGGCTTTCAAGCGGCTGAAGC
CGAAAGGTGTTATCCTTTCAGGCAGCCCCCATTCGACGACTGATATTGGGGCGCCGCGAGCGCCGCAGGCCGTTTTCGAG
GAAGGCATTCCCGTTCTCGGCATCTGCTACGGCGAACAAACGATGTGCGCCCAATTGGGTGGTAAGGTCGAAAGTGGCCA
TGATCGCGAATTCGGTCGTGCTTTCCTGGATGTGCAGGAAGATAGCCCACTCTTCGAAGGCATCTGGGCCAAGGGCACCC
GTCATCAGGTCTGGATGAGCCATGGTGACCGTGTTACGTCGCTGCCCGATGGTTTTACCATTATAGGCACTTCGCCAAAC
GCACCTTTTGCGGCTATCGCTGACGAGAAGCGCAAATATTACGGCGTGCAGTTCCACCCGGAAGTCGTGCATACACCGGA
CGGTGCAAAACTTCTTCAGAACTTCGTTCATCGTATCGTCGGTGTGAAGCCGGGCTGGACCATGGGCGCCTATCGCGAAC
AGGCAGTCGAGGCGATCCGGAAGCAGGTTGGTAGCGGCAAGGTGATCTGTGCGCTTTCCGGCGGTGTGGATTCTTCTGTT
GCAGCACTCCTGGCGCATGAAGCCATCGGCGATCAGCTGACCTGTATTCTGGTTGATCACGGGCTGATGCGTAAAAACGA
AGCTAACCAAGTCGTTGAAATGTTCCGCGAACATTACAACCTGCCGCTCATTCTCGTTGATGCTGCTGATCGTTTCATCG
GTGAGCTGGAAGGCGAAACCGATCCTGAAAAGAAGCGCAAGACGATTGGCCGTCTCTTCATCGAAGTGTTCGAGGAAGAA
GCAAAGAAGCTCGGCGGTGCGGATTTCCTCGTGCAGGGCACGCTCTATCCGGACGTTATCGAAAGCGTTTCGTTTACCGG
CGGTCCTTCTGTCACGATCAAGTCGCACCACAATGTAGGTGGTCTGCCGGAGCGCATGAAGATGCAGCTCGTCGAACCAC
TGCGGGAACTGTTCAAGGACGAGGTACGCTTGCTCGGCAAGGAACTCGGCCTGCCGGATAGCTTCATCGGCCGCCATCCG
TTCCCGGGACCGGGTCTCGCTATCCGCTGCCCGGGCGGTATTACGCGCGAGAAACTCGAGATTCTGCGCGAAGCCGACGC
GATCTATCTGGATGAAATCCGCAAGGCTGGTCTCTATGATGCCATCTGGCAGGCTTTCGCCGTTCTGTTGCCGGTTCAGA
CCGTGGGCGTGATGGGCGATGGCCGTACCTACGAATTCGTCTGCGCACTGCGCGCCGTGACGTCTGTGGACGGCATGACC
GCCGATTTTTACCATTATGACATGAACTTTCTTGGCAATGCGGCAACTCGCATCATCAACGAGGTACGCGGCATCAATCG
TGTTGTTTATGACGTGACCTCAAAGCCGCCCGGCACGATCGAGTGGGAATGA

Protein sequence :
MLHMSTTAHPDTILIIDFGSQVTQLIARRVREANVYCEIVPFQSAEEAFKRLKPKGVILSGSPHSTTDIGAPRAPQAVFE
EGIPVLGICYGEQTMCAQLGGKVESGHDREFGRAFLDVQEDSPLFEGIWAKGTRHQVWMSHGDRVTSLPDGFTIIGTSPN
APFAAIADEKRKYYGVQFHPEVVHTPDGAKLLQNFVHRIVGVKPGWTMGAYREQAVEAIRKQVGSGKVICALSGGVDSSV
AALLAHEAIGDQLTCILVDHGLMRKNEANQVVEMFREHYNLPLILVDAADRFIGELEGETDPEKKRKTIGRLFIEVFEEE
AKKLGGADFLVQGTLYPDVIESVSFTGGPSVTIKSHHNVGGLPERMKMQLVEPLRELFKDEVRLLGKELGLPDSFIGRHP
FPGPGLAIRCPGGITREKLEILREADAIYLDEIRKAGLYDAIWQAFAVLLPVQTVGVMGDGRTYEFVCALRAVTSVDGMT
ADFYHYDMNFLGNAATRIINEVRGINRVVYDVTSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 1e-135 55
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 8e-136 55
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 1e-135 54
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-114 50