Gene Information

Name : Shew185_0813 (Shew185_0813)
Accession : YP_001365033.1
Strain : Shewanella baltica OS185
Genome accession: NC_009665
Putative virulence/resistance : Resistance
Product : beta-lactamase
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG2602
EC number : 3.5.2.6
Position : 952608 - 953495 bp
Length : 888 bp
Strand : +
Note : PFAM: penicillin-binding protein transpeptidase; KEGG: sbl:Sbal_3522 beta-lactamase

DNA sequence :

ATGCGTTCGTTCGCCATATCGACTGTGTTGGTGATGTCCTCACTGTTAGCGTCGTCAATCATAGCTGCCCCGACATTTGC
CTCAACAGCGGCGAAGACGGAGTGGCAAGAAACCCGCAGTTGGGATGCCATTTTTACTCAGCACCAAGTTGAACCGCAAC
AAGCTAAGCAACTACAAGCTAAACCGCAAAAAACTAAGCCCCAACAAGCCTCGGGCGTGGTGGTGCTGTGGAACGAAAAC
AAGCAACAGGGATATACCAACAATCTTAAACGTGCCAATCAAGGTTTTTTACCAGCATCGACCTTTAAAATCCCCAATAG
CTTGATTGCGCTCGAGTTGGGTGTGGTGAAGGATGAGCACCAAGTGTTTAAGTGGGATGGTAAAAGTCGTGATATCGCCA
CTTGGAATCGTGACCACAACTTGATTACCGGGATGAAGTATTCGGTTGTGCCTGTCTATCAAGAGTTTGCCCGCCAAATT
GGTGAGGCGCGGATGTCGAAGATGATCGCCTCCTTCGATTATGGCAATGAGGATATCTCGGGTAACTTAGATAGCTTTTG
GCTCGATGGCGGTATTCGGATTTCTGCCACTGAGCAAATTGATTTCCTGCGTCGGCTTTATCACAACAAGATCCATGCCT
CAGAGCGCAGTCAACGAATCGTTAAGCAAGCCATGCTCACCGAGGCGAATTCTGACTATATTATTCGCGCAAAAACCGGC
TATGCGGTCAGAGCTGAACCAAGTATTGGCTGGTGGGTGGGTTGGGTAGAACTCGATGATAATGTGTGGTTTTTTGCAAT
GAATATGGATATACCCGACGCCGCAGGTTTGCCATTGCGTCAAGCCATCACTAAAGAAGTTTTAAAACTGGAACACGTTA
TTCCTTAG

Protein sequence :

MRSFAISTVLVMSSLLASSIIAAPTFASTAAKTEWQETRSWDAIFTQHQVEPQQAKQLQAKPQKTKPQQASGVVVLWNEN
KQQGYTNNLKRANQGFLPASTFKIPNSLIALELGVVKDEHQVFKWDGKSRDIATWNRDHNLITGMKYSVVPVYQEFARQI
GEARMSKMIASFDYGNEDISGNLDSFWLDGGIRISATEQIDFLRRLYHNKIHASERSQRIVKQAMLTEANSDYIIRAKTG
YAVRAEPSIGWWVGWVELDDNVWFFAMNMDIPDAAGLPLRQAITKEVLKLEHVIP

• Homologs from PAI DB

Gene	GenBank Accn	Product	Virulance or Resistance	PAI or REI	Alignment Type	E-val	Identity
bla OXA-10	CAJ77047.1	Oxacillinase	Not tested	AbaR1	Protein	1e-57	50
blaOXA-129	AET25386.1	OXA-129 beta-lactamase	Not tested	PAGI-2(C)	Protein	4e-53	48
bla OXA-129	AFG30109.1	OXA-129 beta-lactamase	Not tested	PAGI-2	Protein	4e-53	48

• Homologs from CARD and BacMet (resistance genes)

Gene	GenBank Accn	Product	ID of source DB	Alignment Type	E-val	Identity
Shew185_0813	YP_001365033.1	beta-lactamase	HM015773.1.gene6.p01	Protein	9e-97	77
Shew185_0813	YP_001365033.1	beta-lactamase	HQ700343.1.gene1.p01	Protein	1e-93	76
Shew185_0813	YP_001365033.1	beta-lactamase	JN205800.1.gene6.p01	Protein	2e-96	76
Shew185_0813	YP_001365033.1	beta-lactamase	AY500137.1.gene1.p01	Protein	5e-97	72
Shew185_0813	YP_001365033.1	beta-lactamase	AY343493.1.gene1.p01	Protein	2e-70	55
Shew185_0813	YP_001365033.1	beta-lactamase	U37105.2.gene2.p01	Protein	6e-58	50
Shew185_0813	YP_001365033.1	beta-lactamase	AM412777.1.gene1.p01	Protein	3e-57	50
Shew185_0813	YP_001365033.1	beta-lactamase	NC_010410.6002874.p0	Protein	6e-58	50
Shew185_0813	YP_001365033.1	beta-lactamase	X75562.1.gene1.p01	Protein	3e-55	49
Shew185_0813	YP_001365033.1	beta-lactamase	U59183.1.gene3.p01	Protein	3e-57	49
Shew185_0813	YP_001365033.1	beta-lactamase	Z22590.1.gene1.p01	Protein	2e-57	49
Shew185_0813	YP_001365033.1	beta-lactamase	AY445080.1.gene1.p01	Protein	3e-57	49
Shew185_0813	YP_001365033.1	beta-lactamase	AJ854182.1.gene1.p01	Protein	1e-57	49
Shew185_0813	YP_001365033.1	beta-lactamase	AF231133.1.gene3.p01	Protein	6e-56	49
Shew185_0813	YP_001365033.1	beta-lactamase	X58272.1.gene1.p01	Protein	1e-53	49
Shew185_0813	YP_001365033.1	beta-lactamase	AM932669.1.gene2.p01	Protein	3e-53	48
Shew185_0813	YP_001365033.1	beta-lactamase	AY619003.1.gene1.p01	Protein	3e-30	42
Shew185_0813	YP_001365033.1	beta-lactamase	EU086834.1.gene1.p01	Protein	5e-32	42
Shew185_0813	YP_001365033.1	beta-lactamase	EU086830.1.gene1.p01	Protein	6e-32	41
Shew185_0813	YP_001365033.1	beta-lactamase	JF273470.1.gene1.p01	Protein	3e-32	41
Shew185_0813	YP_001365033.1	beta-lactamase	AY423074.1.gene1.p01	Protein	2e-34	41