Gene Information

Name : guaA (Shew185_2998)
Accession : YP_001367192.1
Strain : Shewanella baltica OS185
Genome accession: NC_009665
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 3591973 - 3593550 bp
Length : 1578 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGAGCGATATTCATGAGCACAAGATACTGATCCTCGATTTTGGATCTCAGTACACTCAACTGATTGCCCGTCGTATCCG
TGAAATCGGTGTGTACTGTGAATTATGGGCTTGGGATGTAACAGAAGCCCAAATCCGCGAATTTGCCCCGAATGGTATTA
TTCTTGCTGGCGGACCTGAAAGTGTAACGGCTGAAAACTCGCCGCGTGCGCCTGAATACGTATTTACTGCGGGCGTGCCT
GTACTGGGCATTTGCTACGGCATGCAAACCATGTCTGAGCAGCTGGGCGGTAAAGTGATCCAAGGTGTGGGCGAAGGTGA
ATTCGGCTACGCTCAAATTGAAATGCTGACAGATTCTTTGCTATTCAAAGGCATCGAAGACGCAGTTAACAGCGAAGGCA
AACCCTTACTCGACGTATGGATGAGCCACGGCGATAAAGTGTCGGCCATTCCTGAAGGGTTTGTGGCGGTCGCTAAAACC
GATACTTGCCCATTTGCTGCTATGGCGAACGAAGAGAAGCAATTCTTCGGCGTACAGTTCCACCCTGAAGTGACCCACAC
TCGCCAAGGCATGCGGATGTTATCGCACTTTGCCTTAGACATTTGTGGCTGTGCGGCTAACTGGAAACCTTCCTCTATCA
TCGAAGATGCGATTGAGCGCTTGAAGAAGCAAATCGGCGATGACGAAGTGATTTTAGGGCTATCGGGCGGTGTCGATTCT
TCGGTTGTAGCTATGTTGCTGCACCGCGCTATCGGTAAAAAACTGACCTGCGTATTCGTTGATAACGGTTTATTGCGTTT
GAACGAAGCCGAGCAAGTGATGGAAATGTTTGGCGATCATTTCGGCCTGAATATCATTCACGTTGATGCGGAAAACCGTT
TCCTTGACGCGATGAAAGGCGAAGCCGATCCAGAAGCTAAGCGTAAGATCATCGGCCGTGTATTTGTGGAAATTTTCGAT
GAAGAATCGAAAAAATGCGCTAATGCCAAATGGTTAGCGCAAGGCACGATTTATCCAGACGTGATTGAATCTGCTGGCAG
CGCCACAGGTAAAGCACATGTGATTAAATCTCACCATAACGTTGGCGGTTTGCCAGACGATATGGAACTGGGTTTAGTTG
AGCCACTGCGCGAATTGTTCAAAGATGAAGTGCGCAAAATTGGTCTTGAGTTAGGTCTGCCATACAACATGCTTTATCGT
CATCCGTTCCCAGGACCAGGTCTTGGTGTGCGTGTTTTAGGTGAAGTGAAGAAAGAATACTGTGACTTATTGCGCCGCGC
CGATGCTATCTTCATCGAAGAACTGCATAAAGCCGACCTGTACAATAAAGTCAGCCAAGCCTTTACTGTGTTCTTACCTG
TACGCTCAGTCGGTGTTATGGGTGATGGCCGTAAATATGATTGGGTTGTGTCACTGCGCGCCGTTGAAACCGTTGATTTT
ATGACGGCCCATTGGGCACATCTGCCCTATGATTTCTTAGGTCGCGTATCGAACCGCATCATCAACGAAGTCGATGGTAT
TTCCCGTGTGGTTTACGATATTTCTGGCAAGCCGCCAGCGACTATCGAATGGGAATAG

Protein sequence :
MSDIHEHKILILDFGSQYTQLIARRIREIGVYCELWAWDVTEAQIREFAPNGIILAGGPESVTAENSPRAPEYVFTAGVP
VLGICYGMQTMSEQLGGKVIQGVGEGEFGYAQIEMLTDSLLFKGIEDAVNSEGKPLLDVWMSHGDKVSAIPEGFVAVAKT
DTCPFAAMANEEKQFFGVQFHPEVTHTRQGMRMLSHFALDICGCAANWKPSSIIEDAIERLKKQIGDDEVILGLSGGVDS
SVVAMLLHRAIGKKLTCVFVDNGLLRLNEAEQVMEMFGDHFGLNIIHVDAENRFLDAMKGEADPEAKRKIIGRVFVEIFD
EESKKCANAKWLAQGTIYPDVIESAGSATGKAHVIKSHHNVGGLPDDMELGLVEPLRELFKDEVRKIGLELGLPYNMLYR
HPFPGPGLGVRVLGEVKKEYCDLLRRADAIFIEELHKADLYNKVSQAFTVFLPVRSVGVMGDGRKYDWVVSLRAVETVDF
MTAHWAHLPYDFLGRVSNRIINEVDGISRVVYDISGKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 1e-124 51
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 1e-124 51
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 1e-124 51
guaA NP_938969.1 GMP synthase Not tested Not named Protein 1e-109 47