Gene Information

Name : leuS (Krad_3443)
Accession : YP_001363170.1
Strain : Kineococcus radiotolerans SRS30216
Genome accession: NC_009664
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : -
Position : 3525224 - 3527791 bp
Length : 2568 bp
Strand : +
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
GTGCGGGACGCACGGACGCACCGGGAGGACGAGATGACGCAGACGGACACGCAGGCCACGGGGCCCGACCGCGCCGAGGA
GCAGGACGGGCAGCGCTACGACGCGTTCGCCCTGCAGGAGAAGTGGTTGCCCGTCTGGGACGAGCGCAAGCCGTTCCGGA
GCGGTGAACCGGGCGACGAGCGCCCGAAGAAGTACGTGCTGGACATGTTCCCCTACCCCTCGGGGGACCTGCACATGGGT
CACGCCGAGGCCTACGCCCTCGGCGACGTCATCGCGCGGTACTGGCTGCAGCGCGGGTTCGACGTCATGCACCCCATCGG
CTGGGACGCCTTCGGCCTGCCCGCCGAGAACGCCGCCATCAAGCGCGGCCTGGACCCGCGGCGGTGGACCTACGACAACA
TCGCCCAGCAGCGCGCCTCGATGCGCCGCTACGCGTGCTCCTTCGACTGGGACCGGGTCCTGCACACCTCCGACCCGGAG
TACTACCGGTGGAACCAGTGGCTGTTCCTGAAGCTGTACGAGAAGGGCCTGGCCTACCGCAAGGACTCCCTGGTCAACTG
GGACCCGGTCGACCAGACGGTGCTGGCCAACGAGCAGGTGCTGCCCGACGGCACCTCCGAGCGCTCCGGCGCGAAGGTGG
TCAAGAAGAAGCTGACCCAGTGGTACTTCCGGATCACCGAGTACGCCGACCGGCTGCTGGACGACCTGGACACCCTGGAG
GGCCAGTGGCCGGCCAAGGTCATCTCGATGCAGCGCAACTGGATCGGGCGCTCCACCGGCGCTGAGGTCGAGTTCGCCAT
CGAGGGCCGCGACGAGCCCGTCACCGTCTACACGACGCGCCCGGACACCCTGCACGGCGCGACGTTCATGGTCGTCGCCG
CCGACTCCGACCTGGCCGAGGAGCTCGCCGCCGGCGCCCCCGACGACGTCCGCGCGGCGTTCGAGGCGTACCGCACCCAG
GTGCAGGAGACCTCCGACATCGACCGGCTGTCCTCCGAGCGGGAGAAGACCGGCGTCCCGCTGGGCCGGTACGCGGTCAA
CCCCGTCAACGGGGAACGGCTGCCGATCTGGGCCGCCGACTACGTGCTGGCCGACTACGGCACCGGCGCCATCATGGCCG
TGCCCGCCCACGACCAGCGCGACCTCGACTTCGCCCGGGCGTTCGGCCTGCCCGTCCGCGTCGTCGTCGACGTGCGCGAC
GACGACGGGAACCCGCTGCCGGACCCGGCGGAGTCCGGGACCGCCACCGCCGGCGACGGCGTCCTGGTGAACTCCGGCGC
GCTGGACGGGCTGGGCAAGCAGGCCGGCATCGCGAAGGCGATCGAGGACCTGACCGCCGCCGGGAAGGGCCGCGCGGCCA
AGAACTACCGCCTGCGCGACTGGCTGATCTCGCGCCAGCGCTACTGGGGCACGCCCATCCCGGTGGTGCACACCGAGAAC
GGCGAGGTCCCCGTCCCCGAGGACCAGCTGCCGGTCCTGCTGCCGCCGAGCGAGGGGCTGAACCTGACCCCCAAGGGCAC
CTCGCCGCTGGGCGCGGCCGAGGACTGGGTCAACGTGCCCAGCCCCGTCGACGGTTCCCCCGCGCGCCGCGACCCGGACA
CGATGGACACGTTCGTCGACTCCTCCTGGTACTTCCTGCGCTTCGTGTCCCCGCACGACGACACGAAGGCCTTCGACACC
GACCTCATCGCGCAGTGGGGTCCCGTCGACCAGTACGTCGGCGGCGTCACCCACGCGATCCTGCACCTGCTCTACGCCCG
CTTCATCACCAAGGTGCTGCACGACCTGGGGTACCTGCCCTTCGACGAGCCCTTCACCCGCCTGCTCAACCAGGGCATGG
TGCAGATGGACGGTTCGGCGATGAGCAAGTCGAAGGGCAACATCGTCCGGCTCTCCGACCAGCTGGAGGAGCACGGCGTC
GACGCCATCCGGCTCACCATGGCGTTCGCGGGCCCGCCCGAGGACGACATCGACTGGGCCGACGTGTCCCCCTCGGGTTC
CGCGAAGTTCCTGGGCCGGGCCTGGCGCCTGGCCCGCGACGTCACCTCCGAGCCCGGGGTCGACCCCACCACCGGGGACG
CCGCCCTGCGGTCGGTGACCCACCGGACCCTGCACGAGGTGTCCCAGCACGTCGAGGCGTTCCGCTTCAACGTCGCCGTC
GCCCGCCTCATGGAACTGGTCAACGCCACCCGCAAGGCCATCGACTCCGGGCCCGGGGCCGGTGACCCCGCCGTCCGCGA
GGCCGTCGAGGCCACCGCGGTCGTGCTGTCGCTGTTCGCGCCCTACGCGGCCGAGGACATGTGGTCCCTGCTGGGGCACG
ACCCGTGCGTGGCGCGGGCCGGGTGGCCCGCCGTCGACGAGTCGCTGCTCGTCCAGGACACCGTCACCTGCGTCGTCCAG
GTGCAGGGCAAGGTGCGCGACCGCCTCGAGGTGTCCCCGGACATCACCCAGGACGCGTTGCGGGAACTGGCCCTGGCCTC
GGAGAAGGTCCAGGCCGCCCTCGGCGGGCGCGACCTGCGGACGGTCGTGGTCCGCGCGCCCAAGCTCGTCAACATCGTCC
CCGCCTGA

Protein sequence :
MRDARTHREDEMTQTDTQATGPDRAEEQDGQRYDAFALQEKWLPVWDERKPFRSGEPGDERPKKYVLDMFPYPSGDLHMG
HAEAYALGDVIARYWLQRGFDVMHPIGWDAFGLPAENAAIKRGLDPRRWTYDNIAQQRASMRRYACSFDWDRVLHTSDPE
YYRWNQWLFLKLYEKGLAYRKDSLVNWDPVDQTVLANEQVLPDGTSERSGAKVVKKKLTQWYFRITEYADRLLDDLDTLE
GQWPAKVISMQRNWIGRSTGAEVEFAIEGRDEPVTVYTTRPDTLHGATFMVVAADSDLAEELAAGAPDDVRAAFEAYRTQ
VQETSDIDRLSSEREKTGVPLGRYAVNPVNGERLPIWAADYVLADYGTGAIMAVPAHDQRDLDFARAFGLPVRVVVDVRD
DDGNPLPDPAESGTATAGDGVLVNSGALDGLGKQAGIAKAIEDLTAAGKGRAAKNYRLRDWLISRQRYWGTPIPVVHTEN
GEVPVPEDQLPVLLPPSEGLNLTPKGTSPLGAAEDWVNVPSPVDGSPARRDPDTMDTFVDSSWYFLRFVSPHDDTKAFDT
DLIAQWGPVDQYVGGVTHAILHLLYARFITKVLHDLGYLPFDEPFTRLLNQGMVQMDGSAMSKSKGNIVRLSDQLEEHGV
DAIRLTMAFAGPPEDDIDWADVSPSGSAKFLGRAWRLARDVTSEPGVDPTTGDAALRSVTHRTLHEVSQHVEAFRFNVAV
ARLMELVNATRKAIDSGPGAGDPAVREAVEATAVVLSLFAPYAAEDMWSLLGHDPCVARAGWPAVDESLLVQDTVTCVVQ
VQGKVRDRLEVSPDITQDALRELALASEKVQAALGGRDLRTVVVRAPKLVNIVPA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 1e-156 43