Gene Information

Name : guaA (Krad_0749)
Accession : YP_001360502.1
Strain : Kineococcus radiotolerans SRS30216
Genome accession: NC_009664
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 1536134 - 1537777 bp
Length : 1644 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
GTGGTGACGCCGGACGCGCCCGAGACCCAGGTTGAGACCACCCCCGACACCCGGCCCGCCGAGGTGGAGGCCGAACGCGC
GCACCGCCCCGTGCTCGTCGTCGACTACGGGGCCCAGTACGCGCAGCTCATCGCGCGCCGGGTCCGCGAGGCCGACACGT
ACTCGGAGATCGTCCCCAGCTCCACGCCGGTGGCGGAGATCCTGGCCAAGGACCCCGCCGCGGTGATCCTCTCCGGCGGC
CCGTCCAGCGTGTACGCCGAGGGCGCCCCGCAGGTCGACCCGGCGCTGTTCGAGGCCGGGGTCCCCGTCCTGGGCATCTG
CTACGGGTTCCAGGCCATGGCCAAGGCGCTGGGCGGGGAGGTCGCCCGCACCGGCCAGCGCGAGTACGGCGGGACGGCGG
CGGCGCTGCCGAACGCCGCGGAGTCCACCCTGCTGCGCGACCAGCCGGCCGAGCAGCCGGTGTGGATGTCGCACGGGGAC
AGCGTGTCCCGCGCCCCGGAGGGCTTCCGCGTCACCGCCTCCACCGACGGCACGCCCGTCGCGGCCTTCGAGGACGACGA
GCGCCGCCTCTACGGCGTGCAGTGGCACCCGGAGGTCAAGCACTCCACCCACGGCCAGGACGTCCTGGTGAACTTCCTGC
GCCACGGCGCGGGCATCGACCCGGACTGGACGACCGGCAACGTCATCGAGGAGCAGGTCGCGCGGATCAAGGCCCAGATC
GGCGACGGCAAGGTCATCTGCGCCCTCTCCGGCGGGGTCGACTCCGCGGTGGCCGGGGCCCTGGTGCAGCGCGCGGTGGG
CGACCAGCTCACCTGCGTCTTCGTCGACCACGGCCTGCTGCGCGCCGGGGAGGCCGAGCAGGTCGAGAAGGACTTCGTCG
CCGCGACCGGCGTCAAGCTGCACGTCGTCGACGCCGTGCAGCGCTTCGCCGACGCCCTCGACGGGGTCAGCGACCCGGAG
CAGAAGCGGAAGATCATCGGCCGCGAGTTCATCCGCGTCTTCGAGCAGGCCGCGCGCGACGTCGTCGCCAAGGAGGGCAC
CGACGGCGGCGAGGTGAGGTTCCTCGTCCAGGGGACCCTGTACCCCGACGTCGTGGAGTCCGGCGGCGGCACCGGCGCGG
CGACGATCAAGAGCCACCACAACGTCGGCGGGCTGCCCGACGACCTCGCCTTCGAGCTCGTCGAACCGCTGCGCGCGCTG
TTCAAGGACGAGGTCCGCGCCGTGGGCGTGCAGCTCGGGCTGCCCGAGGCGATGGTCTACCGCCAGCCGTTCCCGGGTCC
GGGCCTGGCCATCCGCATCGTCGGTGCGGTCACCCCCGAGCGCCTGGAGATCCTGCGCGCGGCCGACGCCATCGCGCGCG
CCGAGCTCACCGCCGCGGGCCTGGACCGCGACATCTGGCAGTGCCCGGTCGTGCTGCTCGCCGACGTCCGCTCGGTGGGC
GTGCAGGGCGACGGGCGCACCTACGGCCACCCGGTCGTGCTGCGCCCGGTGTCCTCGGAGGACGCCATGACCGCGGACTG
GACGCGCCTGCCCTACGACGTGCTGGCGAGGATCTCCACCCGCATCACCAACGAGGTCCCCGAGGTCAACCGCGTGGTCC
TCGACGTCACGAGCAAGCCGCCGGGCACCATCGAGTGGGAGTGA

Protein sequence :
MVTPDAPETQVETTPDTRPAEVEAERAHRPVLVVDYGAQYAQLIARRVREADTYSEIVPSSTPVAEILAKDPAAVILSGG
PSSVYAEGAPQVDPALFEAGVPVLGICYGFQAMAKALGGEVARTGQREYGGTAAALPNAAESTLLRDQPAEQPVWMSHGD
SVSRAPEGFRVTASTDGTPVAAFEDDERRLYGVQWHPEVKHSTHGQDVLVNFLRHGAGIDPDWTTGNVIEEQVARIKAQI
GDGKVICALSGGVDSAVAGALVQRAVGDQLTCVFVDHGLLRAGEAEQVEKDFVAATGVKLHVVDAVQRFADALDGVSDPE
QKRKIIGREFIRVFEQAARDVVAKEGTDGGEVRFLVQGTLYPDVVESGGGTGAATIKSHHNVGGLPDDLAFELVEPLRAL
FKDEVRAVGVQLGLPEAMVYRQPFPGPGLAIRIVGAVTPERLEILRAADAIARAELTAAGLDRDIWQCPVVLLADVRSVG
VQGDGRTYGHPVVLRPVSSEDAMTADWTRLPYDVLARISTRITNEVPEVNRVVLDVTSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA NP_938969.1 GMP synthase Not tested Not named Protein 0.0 70
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 2e-139 53
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 1e-139 53
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 9e-140 53