Gene Information

Name : lysS (SUN_0482)
Accession : YP_001357799.1
Strain : Sulfurovum sp. NBC37-1
Genome accession: NC_009663
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : 6.1.1.6
Position : 490553 - 492196 bp
Length : 1644 bp
Strand : -
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
TTGATATTTGATAATCAATATATTCAGGAACGAATCAAAAAAACTGAAAAACTGAGAGAAGAGGGGATGAATCCCTATCC
GGCGAACATTACAAAAGGTATGCCCTCTTCGGACTTCTTTGAGCACTATGCCTACGTAAAAGAGCAGACGACAGATGAGA
AAAAAGATGAGGGGCAGACCGTTACCCTGACAGGACGGATCAAGTTCATACGTATCATGGGAAAAGCCGCTTTTGCCAAG
ATAGAAGACACTGACGGCCTTGTACAGATCTATTACAACCGTGACGACCTTCCCGAAGGCTACTACAACACTGTAGCGAA
GAAACTTTTCGAAGTGGGCGATATTATTGAAGCGACCGGCTACCCTTTCGTGACACAGACAGGCGAACTTACCCTGCACT
GCAAGGACCTCAAGATCGTTTCCAAAGCGATCATGCCGCTTCCGGAAAAGTTCCACGGCCTGACCGACCATGAGATCCGC
TACCGACAGCGTTACCTCGACATGATCATGAACCCGGAGGTCAAAGAGACCTTCATCATGCGCTCCAAGATCGTTTCACT
CATCAGACGCTTCTTTGAGGACCACAGCTTCCTCGAAGTCGAAACACCGATGATGCACCCCATCCCCGGCGGCGCGAATG
CAAAGCCGTTCGTGACCCATCACAATGCACTGGGCGTGGACAGATATCTTAGAATCGCGCCGGAGCTTTACCTCAAGCGT
CTGACGGTCGGCGGTATGGAAGCGGTCTTCGAGATCAACCGTAACTTCCGTAACGAGGGGATGGACCAGACACACAATCC
CGAATTCACCTCCATCGAGTTCTACTGGGCTTATCACAACTATCTTGACCTGATGAGGCTGACGGAGGAGCTCTTCGAAT
ATATCTTTGCCCAGCTGCAGATGGACAAAACCATCACCTACGGCGAGTATGAGATTGACTGTTCAACACCGTTCGCCAAA
GTACCCTTCGTGGAAGCACTGACCAGCATCGGCGAGGTACCCGCAGAGGTTGCCACAGGCAGAGAGAAAGCGATCGCCTA
CCTCAAAGAGCATGGTGTAGAGGTCAACCCTAATCTCACACTGGGCTATCTGCAAGCAGAACTTTTCGACGAGTTCGTCG
AAGGCAAGCTGATCAACCCGACGTTCATTACGGACTACCCTATCGATATTTCACCGCTTTCAAGAAGAAGTGATGACAAT
CCCGAGATCGCCGAACGCTTCGAGCTTTTCATGGCAGGCAAGGAGATCGCCAACGGCTTCAACGAGCTCAACGACCCAAT
CGACCAGTTCGAACGTTTCAAGGCACAGGCAGACGCCAAAGAGGCGACCGGTGATGAAGAGACCATGCATATGGACCTCG
ACTTCATCCGGGCTCTGGGACACGGTATGACACCGACTGCTGGAGAGGGTATCGGTATCGACCGCCTGGTAATGATGCTG
ACCGACAACCACTCCATCCGTGACGTCATCCTCTTCCCGGCCATGAAGCCAGAAGCAAAACTTGAAGAGGCCAAAGCGGA
GATCGCCTGCAAAAAGTGCGGCAATACCAATGAAGAGGAGCTCAAACCTGCCAAGAAAGGCAAAGGGTTCTTCTGTAAAG
ATGCGGCTGCCTGCAATAAGAGAGCACAGGAGAAGAAGGCCTGA

Protein sequence :
MIFDNQYIQERIKKTEKLREEGMNPYPANITKGMPSSDFFEHYAYVKEQTTDEKKDEGQTVTLTGRIKFIRIMGKAAFAK
IEDTDGLVQIYYNRDDLPEGYYNTVAKKLFEVGDIIEATGYPFVTQTGELTLHCKDLKIVSKAIMPLPEKFHGLTDHEIR
YRQRYLDMIMNPEVKETFIMRSKIVSLIRRFFEDHSFLEVETPMMHPIPGGANAKPFVTHHNALGVDRYLRIAPELYLKR
LTVGGMEAVFEINRNFRNEGMDQTHNPEFTSIEFYWAYHNYLDLMRLTEELFEYIFAQLQMDKTITYGEYEIDCSTPFAK
VPFVEALTSIGEVPAEVATGREKAIAYLKEHGVEVNPNLTLGYLQAELFDEFVEGKLINPTFITDYPIDISPLSRRSDDN
PEIAERFELFMAGKEIANGFNELNDPIDQFERFKAQADAKEATGDEETMHMDLDFIRALGHGMTPTAGEGIGIDRLVMML
TDNHSIRDVILFPAMKPEAKLEEAKAEIACKKCGNTNEEELKPAKKGKGFFCKDAAACNKRAQEKKA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 1e-105 48

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_001357799.1 lysyl-tRNA synthetase VFG1668 Protein 6e-106 48