Gene Information

Name : guaA (SUN_1897)
Accession : YP_001359201.1
Strain : Sulfurovum sp. NBC37-1
Genome accession: NC_009663
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 1951837 - 1953378 bp
Length : 1542 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGAAGCAAGTACCTATCTTAGTTTTGGATTTCGGTTCCCAGTATACACAGCTCATTGCCAGAAAACTCAGGGAATCGGG
TGTCTACACGGAAGTGGTGCCGTATCGTGAAAGCATTGAGGATATCAAAGCAAGAAAGCCGCAGGGAATCATCCTCTCGG
GAGGGCCGGCTTCGGTCTATGCGGAAGATGCTTACAAACCAGATGAGGGCATCTGGGATCTTGGCTTACCTATTCTAGGT
ATCTGCTACGGTATGCAGTTAATCACTCAGCACTTCGGCGGTTCGGTAATCGCTGCGGATCATCATGAATACGGCAAAGC
AAAACTACATATCGAGAATGAGAATTCCCCCATCTTTAAAGATGTGGCACAGGATTCTATCGTATGGATGAGTCATGGTG
ACAGGGCGGAGAGACTGCCTGAAGGTTTTGAAGTTGTGGGTACGAGTGAGAACTCTCCCTATGCAGCTATTGCCAATGAA
TCAAAACATATCTATGCCTTCCAGTTCCACCCTGAGGTACACCACTCCGTAGAGGGTACGCATATGTTGAAGAACTTTGC
CAAATATATTTGCGGATGCGAAAGCACCTGGAACATGGGCTCTTTTGCCAAAGAAAAGATCGCACAGATCAGAGCACAGG
TCGGTGAGAAGAAAGTACTCTGTGGCGTTTCCGGCGGTGTAGATTCATCCGTAGTGGCTGCCATGCTGCATGAGGCACTG
CCCAAAGAACAGCTGATCTGCGTATTTGTCGACCAGGGGCTGTTGCGTAAAGATGAAGCAGAACAGGTTCAGGATATGTT
CAAGCTTCTTGACATCCCCCTTATTACCATCGATGCAAAAAAAGAGTTCATGGAAGCACTTGCCGGTGTAACCGACCCGG
AACAGAAACGTAAAGCGATCGGCGAGAAGTTCATTGAAGTCTTTGACAAGGAAGCGGGTAAACATACCGATGTCTCCTTC
CTTGCACAAGGTACGCTTTACACGGATGTAATTGAATCGGTCTCCGTCAAAGGGCCTTCCAAAACAATCAAGTCCCACCA
CAACGTAGGAGGATTACCTGACTGGATGACCTTTGAACTGGTCGAACCGCTTCGTGAGATATTTAAGGATGAAGTACGTA
AGCTTGGGCTTGAACTCGGTCTCCCCAAACATATGATCGGCCGTCACCCTTTCCCAGGACCCGGACTGGCAATACGCGTC
ATGGGAGAGGTGAATGAAGAGGCGCTCAGACTACTGCGTGAATCGGATGCCATCATGCAGGAAGAGCTCAGATCGACCGG
TTATTACGATAAGGTCTGGCAGGCATTTACCGTACTGCTCAATGTACAGTCCGTAGGTGTTATGGGAGACAACAGAACGT
ATGACAACACGGTCTGTGTACGTATGGTGGAATCGGTCGACGGTATGACCGCGACCTTTGCGCATATCCCTCATGATGTG
CTTGAAGGGATCAGCAGACGGATCATCAATGAGATCGACGGGATCAACAGGGTGGTGTATGATATATCTTCCAAGCCCCC
AGCCACAATAGAATGGGAGTAA

Protein sequence :
MKQVPILVLDFGSQYTQLIARKLRESGVYTEVVPYRESIEDIKARKPQGIILSGGPASVYAEDAYKPDEGIWDLGLPILG
ICYGMQLITQHFGGSVIAADHHEYGKAKLHIENENSPIFKDVAQDSIVWMSHGDRAERLPEGFEVVGTSENSPYAAIANE
SKHIYAFQFHPEVHHSVEGTHMLKNFAKYICGCESTWNMGSFAKEKIAQIRAQVGEKKVLCGVSGGVDSSVVAAMLHEAL
PKEQLICVFVDQGLLRKDEAEQVQDMFKLLDIPLITIDAKKEFMEALAGVTDPEQKRKAIGEKFIEVFDKEAGKHTDVSF
LAQGTLYTDVIESVSVKGPSKTIKSHHNVGGLPDWMTFELVEPLREIFKDEVRKLGLELGLPKHMIGRHPFPGPGLAIRV
MGEVNEEALRLLRESDAIMQEELRSTGYYDKVWQAFTVLLNVQSVGVMGDNRTYDNTVCVRMVESVDGMTATFAHIPHDV
LEGISRRIINEIDGINRVVYDISSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 3e-139 56
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 2e-139 56
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 2e-139 56
guaA NP_938969.1 GMP synthase Not tested Not named Protein 6e-116 50