Gene Information

Name : thiC (NIS_0596)
Accession : YP_001356067.1
Strain : Nitratiruptor sp. SB155-2
Genome accession: NC_009662
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 595524 - 596858 bp
Length : 1335 bp
Strand : +
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
ATGAGAAAAGAGTGGGTTGAAAAACGAAAAAAAGATAGTGTTCGTACACAGATGTATTATGCAAGACAAGGTATTGTCAC
TGAAGAGATGGAGTATGTTGCAAAAGTCGAAGGACTCGATCCGGAGCTCATCCGAAAAGAGGTGGCACGAGGTCGAATGA
TCATTCCAGCAAATATCAATCATCTGCATCAAAAGCCGATGGCGATAGGAATCGCAGCAAAGTGTAAAATCAATGCGAAT
ATCGGAAGCTCTGCTTTGGCCAGTGATGCGGCAGGGGAAGTTGAAAAGGTAAAAGTGTGCCAAAAGTACGGTGCCGACAC
GATTATGGATCTCTCCACGGGAGGCGATCTTGATGCGATACGAGAAGAGGTGATCAAGCATGCGGAAGTTCCCATAGGAA
CAGTTCCCATCTATCAGATTTTGCATGATTGCAACAATAAAATAGAAGATTTGACTATTGACAAGATGCTAGAAGTGATT
GAACGCCAAGCACAGCAAGGGGTGAGCTATTTTACGATCCATGCGGGATTTTTGCTTCGATTCATGCCTTTAGTTGCCAA
AAGGAAAATGGGGATCGTTTCTAGGGGCGGTAGTTTGATGGCTGCATGGATGATGCATTACCATAAAGAGAATCCATTCT
ATACAGCTTTTGACGATATTTTGGATATTTGTCGAAAATATGACGTGAGTCTCTCGTTGGGAGACAGTCTCAGACCTGGT
TGCTTGGCTGATGCGAGTGACGATGCACAGCTTGAGGAGTTGAAAGTTTTGGGAGAACTCACTCTCAAAGCATGGGATAA
AGATGTGCAGGTAATGATAGAGGGACCTGGACATGTTCCGATGAATCAGATTGAGCGAAATATCAAAATTGAGCGTGACT
ACTGTCATGAAGCGCCATTTTATGTTTTAGGACCTCTTGTTACAGATATTGCCGCCGGATATGATCATCTCGCAAGTGCC
ATAGGCGCTGCAATGGCTGGATGGTATGGAGCGAGTATGCTTTGCTATGTCACACCAAAAGAGCATTTGGGTCTTCCGAA
TGCCGAGGATGTGAGAGAGGGAATAGTTGCATACAAAATTGCGGCCCATGCAGCGGATATTGCCAGAGGAAGAAAAGGGG
CACGTGATGTGGATGATGCTATGAGTGATGCAAGATATAAATTTGACTGGAATAAGCAGTTCGAATTGGCACTCGATCCG
GATCGAGCGAGAGAGTATCACGATGAGACATTGCCGCAAGATGTTTTTAAAGAAGCGGAATTTTGTTCCATGTGTGGACC
AAAGTTTTGTAGCTACAAAATTACACAAGATATCCTCGAAAAACATGGAGCATAG

Protein sequence :
MRKEWVEKRKKDSVRTQMYYARQGIVTEEMEYVAKVEGLDPELIRKEVARGRMIIPANINHLHQKPMAIGIAAKCKINAN
IGSSALASDAAGEVEKVKVCQKYGADTIMDLSTGGDLDAIREEVIKHAEVPIGTVPIYQILHDCNNKIEDLTIDKMLEVI
ERQAQQGVSYFTIHAGFLLRFMPLVAKRKMGIVSRGGSLMAAWMMHYHKENPFYTAFDDILDICRKYDVSLSLGDSLRPG
CLADASDDAQLEELKVLGELTLKAWDKDVQVMIEGPGHVPMNQIERNIKIERDYCHEAPFYVLGPLVTDIAAGYDHLASA
IGAAMAGWYGASMLCYVTPKEHLGLPNAEDVREGIVAYKIAAHAADIARGRKGARDVDDAMSDARYKFDWNKQFELALDP
DRAREYHDETLPQDVFKEAEFCSMCGPKFCSYKITQDILEKHGA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 2e-114 58
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 2e-114 58
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 1e-110 57