Gene Information

Name : NIS_0258 (NIS_0258)
Accession : YP_001355729.1
Strain : Nitratiruptor sp. SB155-2
Genome accession: NC_009662
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.1
Position : 244792 - 246732 bp
Length : 1941 bp
Strand : +
Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo

DNA sequence :
ATGAATGAAGCGATGATGCAAAAAATGGCAAATACCATCCGGTTTTTGGCTCTTGATATGATACAAAAAGCCAATAGTGG
CCATCCAGGTGCTCCATTGGGTCTTGCTGATATTGCTGTAGTACTTTCACGCCATCTCAAACACAATCCTAAAAATCCAA
AATGGCTCAATCGAGATCGACTTGTTTTTAGTGGAGGACATGCCACAGGTCTAATCTACTCTCTTTTATATTTGTGGGGA
TATGATATCAGTTTGGAAGATCTTAAAGAGTTTCGCCAATTTGGAAGCAAAACACCGGGTCACCCTGAATATGGACACAC
ACCCGGAGTAGAAATCACTACAGGTCCTTTGGGGCAAGGTGTTGCCAATGCAGTGGGAATGGCGATGGCCAGCAAATATC
TTGGCAATCTTCTCAATTCAAAAACCACAAAAATCATCGATCATAAAGTCTATTGTATGTGCGGTGACGGAGACCTGGAA
GAGGGTATTAGTTATGAAGCGTGTGCATTGGCGGGCCGCTTTGAGCTTGATAATCTGATAATGATTTATGACAGCAACCA
TATTACTATCGAAGGCGATACCGCGATAGCATGGAATGAAGATGTATTGGAGCGTTTTCGGGCACAAAATTGGGATGTAA
TCGAAATCGATGGGCATAATTATAATGAGATCGACGCTGCCCTTACATGGGCAAAAAATAGAAAAAAACCGGTTTTGATC
AAAGCAAATACGATCATTGCAAAAGGCAGTTGCCACTATGAAGGGGATCCTCACTCGCATGGTGCACCACTTGGAGAAGA
GGATATTCGATGTGCAAAGAAGAAAGCAGGCTTTCCAGAAGATAAAGCGTTTTATGTACCAGAAGATGTATTGGTTCGAT
TTCGATGTGCCGTTGAAGAGGGGGATTTGGCTGAGCGAGAGTGGAAAAAACTCATTTTCGAGTCCCCGTATAAGGAACAG
GTAGATTTGCTTGAAAGATTGCAAAACCCTGATTTTGATGTGATAGAATGGCCAGAGTTTGAACCGGGGAGCAAAGTGGC
TACGCGAGACAGTAATGGCAAGATTTTAAACGCAATAGCAAAAGCCTTACCTGGTTTTGTAGGAGGAAGTGCCGACCTCG
CTCCATCAAATAAAACCTACTTGCAAGGTATGGGGGATTTCCCAAATGGAAAAAATTTCCATTTCGGTATTCGTGAGCAT
GCTATGGGAGCCATTACAAATGGTATGGCAACTTACGGCTGTTTGGTTCCATTCAATGCAACATTTTTTGTATTCAGTGA
CTATCAAAAAGCGGCAGTTCGGATTGCAGCACTCAGTAGCCTCAAAAACTATTTTATCTGGACGCACGATAGTATCGGTG
TTGGCGAAGATGGACCGACACACCAGCCAATCGAGCAACTAACTACGTTTAGAGCACTCCCGAATTTTTATACATTCAGA
CCGGCAGATGCAACAGAAAATATAGAGTGCTGGAAAGTAGCATTGAAGCTAGAGAAACCAAGTGGATTTGTTTTGAGCAG
GCAAAAACTTGAAGTATTAAAACCGAAAAGAGATTTTGGTGATCCAAGTAGGGGTGCTTACATCATCAAAAAACGGGAAA
ATGCTACTGTAACCCTTTTGGCCAGTGGAAGTGAAGTGATGCTGGCACTTAAAGCCGGATGCCATTTGGAAGAAAAAGGG
ATCAATGCCAACGTGGTGAGTATGCCTTGTATGGAGCTCTTCTTGGAACAAGATCCAGAATATCAAAAAGAGGTACTTAA
TCCATCAACGAAAGTCTTGGCAGTTGAAGCAGCTGCTGGAATTGAACTCTACCGCTTCGCGGATGCAATGATCAGCATGG
AAAACAGATTTGGCGCCAGTGGTCCTGGAGATGTACTTTTTAAAGAGTATGGCTTTACGATAGCTAACATTATCCAAAAA
GTAGAAGAACTACTTTCATGA

Protein sequence :
MNEAMMQKMANTIRFLALDMIQKANSGHPGAPLGLADIAVVLSRHLKHNPKNPKWLNRDRLVFSGGHATGLIYSLLYLWG
YDISLEDLKEFRQFGSKTPGHPEYGHTPGVEITTGPLGQGVANAVGMAMASKYLGNLLNSKTTKIIDHKVYCMCGDGDLE
EGISYEACALAGRFELDNLIMIYDSNHITIEGDTAIAWNEDVLERFRAQNWDVIEIDGHNYNEIDAALTWAKNRKKPVLI
KANTIIAKGSCHYEGDPHSHGAPLGEEDIRCAKKKAGFPEDKAFYVPEDVLVRFRCAVEEGDLAEREWKKLIFESPYKEQ
VDLLERLQNPDFDVIEWPEFEPGSKVATRDSNGKILNAIAKALPGFVGGSADLAPSNKTYLQGMGDFPNGKNFHFGIREH
AMGAITNGMATYGCLVPFNATFFVFSDYQKAAVRIAALSSLKNYFIWTHDSIGVGEDGPTHQPIEQLTTFRALPNFYTFR
PADATENIECWKVALKLEKPSGFVLSRQKLEVLKPKRDFGDPSRGAYIIKKRENATVTLLASGSEVMLALKAGCHLEEKG
INANVVSMPCMELFLEQDPEYQKEVLNPSTKVLAVEAAAGIELYRFADAMISMENRFGASGPGDVLFKEYGFTIANIIQK
VEELLS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 8e-114 44
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 5e-107 44