Gene Information

Name : hemC (NIS_1020)
Accession : YP_001356487.1
Strain : Nitratiruptor sp. SB155-2
Genome accession: NC_009662
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 1036730 - 1037662 bp
Length : 933 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGAAACTGACTATTGCAACACGTGGGAGTAAACTTGCGCTCTGGCAGTCGAATCATATAAAAGCGCAATTAGAATCTTT
TGGATATGAAGTTGAACTAAAAATTTTCAAAACAAAAGGGGATAAAATTCTTGATACGCCCCTGGCTCTCATTGGTGGGA
AAGGACTTTTTACGAAAGAGCTTGAAGATGCGATGTTGAGAGGCGAAGCCGATCTGGCTGTCCATAGTCTCAAAGATGTG
CCAACCGAACTCCCGGAGGGTCTTGTCCTTGGCGCTATTACGAAAAGAGAGATGACCAATGACTCATTGTTAAGTGAACA
ATATGAAACTTTAGCCGATCTTCCTCCAAATGCGGTTGTAGGGACAACTTCGCTGAGAAGAAGAATGCAGCTGCTGCACC
TACGACCAGATATTTGCATTAAAGATCTCCGAGGTAATGTTGATACGAGAATCAATAAATTAAAAAATGGCGAGTTTGAT
GCGATCATTCTGGCTTATGCCGGTTTAAAGAGACTCGGTATTTTAGAAAGTGTACGTTACGTACATCCTATCGATGAAAA
TACAATGATTCCCGCTATGGGTCAAGCAGCACTAGGGATCGAATGTAGACCAGATGTAGTCGATGTTGTTAAAAAACTTA
ATGATGAAAAAAGTGCCATAGAGACGTTCATAGAAAGAGACTTCATCGATAGACTTCAAGGTGGGTGTCAGGTGCCAATA
GGTGTCCGTGCTTCACTGCTAGAAAACAACGACATCATAGTCAAAGCGGTTATCGGTCTTCCTGATGGCAGCGAACTATT
GAAAGATAAAATCTTTGGCTCAAAAGAGAACTATCATGAACTTGGCAAAGAGTTGGCAGAATCAATGATAGACAATGGTG
CCAAAGAGCTGTTGCAAAGAGCAGAAGCAATGGCTTTCAAGGAGCATAAATGA

Protein sequence :
MKLTIATRGSKLALWQSNHIKAQLESFGYEVELKIFKTKGDKILDTPLALIGGKGLFTKELEDAMLRGEADLAVHSLKDV
PTELPEGLVLGAITKREMTNDSLLSEQYETLADLPPNAVVGTTSLRRRMQLLHLRPDICIKDLRGNVDTRINKLKNGEFD
AIILAYAGLKRLGILESVRYVHPIDENTMIPAMGQAALGIECRPDVVDVVKKLNDEKSAIETFIERDFIDRLQGGCQVPI
GVRASLLENNDIIVKAVIGLPDGSELLKDKIFGSKENYHELGKELAESMIDNGAKELLQRAEAMAFKEHK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 2e-63 52
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 2e-63 52