Gene Information

Name : guaA (mma_2032)
Accession : YP_001353722.1
Strain : Janthinobacterium sp. Marseille
Genome accession: NC_009659
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 2297102 - 2298721 bp
Length : 1620 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGCATTCGAAAATACTCATCCTCGATTTCGGTTCACAGGTCACTCAATTGATCGCACGTCGCGTGCGTGATTCCGGTGT
TTTTTCTGAAGTCTTTCCATACGATGTCAGCGATGAGTTCGTGCGCAATTACGGTGCTGCCGGCGTCATCCTGTCGGGTG
GTCCGAATTCAGTCATCGAAGGAGACGAATCGCCACGCGTACCGCAAGCGGTATTCGAACTGGGTGTGCCGGTCATGGGT
ATTTGCTATGGCATGCAGGCAATGGCCGAACAACTGGGCGGCAAGGTAGAAAACGGCAAGGTGCGTGAATTCGGTTACGC
CGAAGTGCGTGCGCATGGTCATACCGCTTTGTTGAAAGACATCAGCGACTTCACCACGCCTGAAGGCCACGGCATGTTGA
AAGTCTGGATGAGCCACGGCGACAAGGTTAATGAAATGCCACCAGGCTTCAAGCTGATGGCATCGACACCGAATTGCCCA
ATCGCCGGCATGGCTGACGAAGAGCGCCGTATGTATGCCTTCCAGTTCCATCCGGAAGTCACGCACACCGTACAAGGCAA
AGCCATTATCGCGCGCTTTGTGCACGATATTTGCGGCTGTAAATCGGACTGGAATATGCCGGATTACATTGCCGAAGCAG
TGGAAAAAATCCGCCAGCAAGTCGGCAGCGATGAAGTCATCCTCGGTTTGTCCGGCGGCGTCGACAGCAGTGTTGCTGCC
GCCTTGATCCACCGTGCGATCGGCGACCAGCTGACTTGCGTATTTGTCGACCATGGCTTGTTGCGCCTCGATGAAGGCAA
GATGGTCATGGAAATGTTCGCCGAGAGTTTGGGCGTGAACGTGATCCACATTGATGCCGTAGATCAGTTCATGGGTCATC
TGGCTGGTGTCAGCGATCCGGAAGCCAAGCGCAAAATCATCGGTCGCGAATTCGTCGAAGTGTTCCAGGTTGAAGCAGGC
AAACGCAAGAATGCCAAATGGCTGGCGCAAGGCACGATTTATCCGGACGTGATTGAAAGCGCCGGTAAGGGCAAGAAGGG
CCACACCATCAAGAGCCACCACAATGTAGGTGGCTTGCCGGAAACCCTGAACCTGCAATTGCTTGAGCCTTTGCGTGAAC
TGTTCAAGGATGAAGTGCGTAAATTGGGCGTAGCGCTCGGCTTGCCGCACGATATGGTGTATCGCCATCCATTCCCGGGC
CCGGGCCTGGGCGTACGTATCCTGGGTGAAGTGAAAAAAGAATTTGCCGACCTCTTGCGTCGCGCCGATGCCATCTTTAT
CGAAGAATTGCGCAAGACGCCATTCGTTGCCACACCGGGTGCTTCGGAAGCGACCGATAACGGTATCCCGCACCGCAACT
GGTACGACGCCACCAGCCAGGCATTTGCCGTCTTCCTGCCGGTTAAATCGGTGGGCGTGATGGGTGATGGCCGGACCTAT
GAGTACGTGGTGGCCTTGCGTGCCGTACAGACGCAGGATTTCATGACCGCACACTGGGCGCATCTGCCGCATGAATTGCT
GGGCAATGTCTCGAATCGCATCATTAATGAAGTACGCGGGATTAATCGCGTGGTCTACGATATCTCGGGTAAACCACCTG
CGACGATTGAGTGGGAGTAA

Protein sequence :
MHSKILILDFGSQVTQLIARRVRDSGVFSEVFPYDVSDEFVRNYGAAGVILSGGPNSVIEGDESPRVPQAVFELGVPVMG
ICYGMQAMAEQLGGKVENGKVREFGYAEVRAHGHTALLKDISDFTTPEGHGMLKVWMSHGDKVNEMPPGFKLMASTPNCP
IAGMADEERRMYAFQFHPEVTHTVQGKAIIARFVHDICGCKSDWNMPDYIAEAVEKIRQQVGSDEVILGLSGGVDSSVAA
ALIHRAIGDQLTCVFVDHGLLRLDEGKMVMEMFAESLGVNVIHIDAVDQFMGHLAGVSDPEAKRKIIGREFVEVFQVEAG
KRKNAKWLAQGTIYPDVIESAGKGKKGHTIKSHHNVGGLPETLNLQLLEPLRELFKDEVRKLGVALGLPHDMVYRHPFPG
PGLGVRILGEVKKEFADLLRRADAIFIEELRKTPFVATPGASEATDNGIPHRNWYDATSQAFAVFLPVKSVGVMGDGRTY
EYVVALRAVQTQDFMTAHWAHLPHELLGNVSNRIINEVRGINRVVYDISGKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 2e-119 51
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 2e-119 51
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 1e-119 51
guaA NP_938969.1 GMP synthase Not tested Not named Protein 3e-103 47