Gene Information

Name : merA (mma_1749)
Accession : YP_001353439.1
Strain : Janthinobacterium sp. Marseille
Genome accession: NC_009659
Putative virulence/resistance : Resistance
Product : mercuric reductase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1249
EC number : 1.16.1.1
Position : 1981999 - 1983684 bp
Length : 1686 bp
Strand : -
Note : -

DNA sequence :
ATGACCACCCTGAAAATCACCGGGATGACCTGCGACTCGTGCGCGGCTCACGTCAAGGAAGCCTTGGAGAAAGTGCCCGG
CGTGCAATCGGCGCTGGTGTCCTATCCGAAGGGCACAGCGCAACTCGCCATTGAGGCGGGCACGTCATCGGATGCGCTGA
CTACCGCCGTGGCCGGACTGGGCTACGAGGCAACGCTTGCCGATGCGCCACCGACGGACAACCGCGCCGGCCTGCTCGAC
AAGATGCGCGGCTGGATAGGGGCCGCTGATAAGCCCAGTGGCAACGAACGCCCGTTGCAGGTCGTCGTCATTGGTAGCGG
TGGCGCGGCAATGGCGGCAGCACTGAAGGCCGTCGAGCAAGGCGCGCACGTCTCGCTGATCGAGCGCGGCACCATCGGCG
GCACCTGCGTCAACGTCGGCTGCGTGCCGTCCAAGATCATGATTCGCGCCGCCCACATCGCCCATTTACGTCGGGAAAGT
CCGTTCGACGGCGGTATCGCGGCGACTGTGCCTGCGATTGACCGCAGCAAACTACTGGCCCAACAGCAGGCGCGCGTCGA
TGAACTGCGCCATGCCAAGTACGAAGGCATTCTGGACGGCAACCCGGCCATCACCGTTGTACATGGTGAGGCGCGTTTCA
AGGATGAGCAGAGCCTGGTCGTCCGTTTAAACGATGGTGGCGAGCGCGTGGTAGCTTTCGACCGCTGCTTAGTCGCCACG
GGTGCCAGCCCGGCCGTGCCGCCGATTCCGGGCCTGAAAGAGTCACCCTACTGGACTTCCACCGAGGCCCTGGTCAGCGA
CACCCTTCCCGAACGCCTAGCCGTGATCGGCTCGTCGGTGGTCGCGCTGGAACTGGCGCAAGCCTTCGCCCGGCTGGGCA
GCCAGGTCACGATCCTAGCTCGCAACACGCTGTTCTTCCGCGACGACCCGTCCATCGGCGAGGCCGTCACAGCGGCCTTC
CGTGCCGAAGGGATCAAGGTACTGGAACACACGCAAGCCAGCCAGGTCGCGCATGTGAACGGCGAATTCGTGCTGACCAC
GGGACACGGTGAAGTACGTGCCGACAAGCTGCTGGTCGCTACCGGACGGACACCGAACACGCGCAGCCTGGCACTCGACG
CGGCGGGGGTCACCGTCAATGCGCAGGGTGCCATCGTCATCGACAAGGGCATGCGCACCAGCACGCCGCACATTTATGCG
GCTGGCGACTGCACCGACCAGCCGCAGTTCGTCTATGTGGCGGCAGCGGCCGGCACCCGTGCCGCGATCAACATGACCGG
AGGGGATGCTGCCATCAATCTAACCGCGATGCCGGCCGTGGTGTTCACCGATCCGCAAGTAGCAACCGTGGGCTACAGCG
AAGCGGAAGCGCATCACGACGGGATCGAAACCGACAGTCGCACGCTCACGCTCGACAACGTGCCGCGTGCGCTTGCCAAC
TTCGACACACGCGGCTTTATCAAGCTGGTCATCGAGGAAGGTAGCGGACGGCTCATCGGCGTGCAGGTCGTCGCCCCGGA
AGCCGGCGAATTGATCCAGACGGCTGTTCTCGCCATTCGCAACCGCATGACGGTGCAGGAACTGGCCGACCAGTTGTTCC
CCTACCTGACGATGGTCGAGGGGTTGAAGCTCGCGGCGCAGACCTTCAGCAAGGACGTGAAGCAGCTTTCCTGCTGCGCC
GGGTGA

Protein sequence :
MTTLKITGMTCDSCAAHVKEALEKVPGVQSALVSYPKGTAQLAIEAGTSSDALTTAVAGLGYEATLADAPPTDNRAGLLD
KMRGWIGAADKPSGNERPLQVVVIGSGGAAMAAALKAVEQGAHVSLIERGTIGGTCVNVGCVPSKIMIRAAHIAHLRRES
PFDGGIAATVPAIDRSKLLAQQQARVDELRHAKYEGILDGNPAITVVHGEARFKDEQSLVVRLNDGGERVVAFDRCLVAT
GASPAVPPIPGLKESPYWTSTEALVSDTLPERLAVIGSSVVALELAQAFARLGSQVTILARNTLFFRDDPSIGEAVTAAF
RAEGIKVLEHTQASQVAHVNGEFVLTTGHGEVRADKLLVATGRTPNTRSLALDAAGVTVNAQGAIVIDKGMRTSTPHIYA
AGDCTDQPQFVYVAAAAGTRAAINMTGGDAAINLTAMPAVVFTDPQVATVGYSEAEAHHDGIETDSRTLTLDNVPRALAN
FDTRGFIKLVIEEGSGRLIGVQVVAPEAGELIQTAVLAIRNRMTVQELADQLFPYLTMVEGLKLAAQTFSKDVKQLSCCA
G

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
merA ACN81005.1 MerA Hg(II) mercuric ion reductase Not tested AbaR5 Protein 0.0 94
merA CAJ77060.1 Mercuric ion reductase Not tested AbaR1 Protein 0.0 94
merA ABQ57371.1 MerA Not tested SGI1 Protein 0.0 90
merA AGK07021.1 MerA Not tested SGI1 Protein 0.0 90
merA AGK07079.1 MerA Not tested SGI1 Protein 0.0 90
merA AET25397.1 MerA Not tested PAGI-2(C) Protein 0.0 86
merA AFG30120.1 MerA Not tested PAGI-2 Protein 0.0 86
merA YP_006098387.1 mercuric ion reductase Not tested Tn2411 Protein 0.0 86
merA AAN62178.1 mercuric (Hg(II)) reductase Not tested PAGI-2(C) Protein 0.0 80
unnamed ABR13401.1 mercuric reductase Not tested PAGI-5 Protein 0.0 75

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
merA YP_001353439.1 mercuric reductase BAC0652 Protein 0.0 92
merA YP_001353439.1 mercuric reductase BAC0653 Protein 0.0 81
merA YP_001353439.1 mercuric reductase BAC0650 Protein 1e-176 69
merA YP_001353439.1 mercuric reductase BAC0224 Protein 2e-85 41