Gene Information

Name : merA2 (PSPA7_0090)
Accession : YP_001345486.1
Strain : Pseudomonas aeruginosa PA7
Genome accession: NC_009656
Putative virulence/resistance : Resistance
Product : putative mercuric reductase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1249
EC number : 1.16.1.1
Position : 102193 - 103875 bp
Length : 1683 bp
Strand : -
Note : Annotation was generated automatically without manual curation; identified by match to protein family HMM PF00070; match to protein family HMM PF00403; match to protein family HMM PF01266; match to protein family HMM PF02852; match to protein family HMM P

DNA sequence : 
ATGACCGAACTGAAAATCATTGGCATGACCTGCGCATCCTGTGTCGTGCATGTGAAAGAGGCCTTGGAGAAGATTCCGGG
CGTGCATCGGGCGGATGTTTCCTACGCCAGTGGGAGGGCCGAATTGAAGGTCGACGAGGCCGTAAGCCGTGAACAGATGC
AGGCCGCCGTCGAGGCCCTGGGGTATCGAGCGGCGTTCGAAGACATCACGCTACCTACCCGTCCCGGCCTGCTCGATAAG
GCACGGGGCTGGCTGAGCGGTGGCACTGACGCCGGGAAAGAGGGTGACAGGCTTCACGTGGCGGTTATCGGCAGTGGTGG
CGCCGCCATGGCGGCCGCGCTCAAGGCGGTAGAAAGGGGGGCCCGCGTCACCCTGATCGAGCGCGGCATCATCGGCGGCA
CCTGCGTCAACGTCGGCTGCGTGCCCTCCAAGATCATGATTCGCGCCGCGCACGTGGCCCATCTGCGCCGCGAAAGTCCG
TTTGATGGCGGACTGCCCGCCACGCCGCCGCTTGTCTTGCGCGAACGGTTGCTCGCCCAGCAACAGGGTCGTGTCGACGA
ACTGCGCCACGCCAAGTACGAAGGCATTCTGGAAAGCACCCCAGCCATCACCGTGCTGCGTGGCTCCGCCCGCTTCCAGG
ACAGCCACACGCTCAGTGTGGAACTGGTCGAGGGGGGCGAGCGCATCGTGACCTTCGACCGCTGCCTGATTGCCACCGGC
GCCAGTGCGGCCGTGCCGCCGATTCCCGGACTGCAAGATACCCCCTTTTGGAACTCGGAAAAGGCGCTGGCAAGCAGCAG
TATTCCGCAACGGCTCGCCGTGATCGGCTCATCCGTGGTGGCCTTGGAGCTGGCGCAAGCCTTTGCCCGGCTGGGTAGCC
GCGTCACCATCCTGGCGCGCAACTCGCTGTTCTTCCGTGAAGATCCGGCCATCGGCGCAGCGCTGACGGCGGCCTTCCGC
CTGGAGGGCATCGAAGTGCTGGAACAGACGCAAGCCAGCCAGGTGGCCCATGCCAACGGCGAGTTCGTGCTGACCACCAA
GCACGGTGAAGTGCGGGTCGACCAACTGCTCGTCGCCACCGGACGCACGCCCAACACCCACGGCCTGAACCTGGAAGCGG
CCGGCGTGCAGCTGGATGAACGCGGTGCCATCCAGATCGACCAGGGCATGCGCAGCAGCAAAGCGGATATTTATGCGGCC
GGCGACTGCACCAACCAGCCGCAGTTCGTCTATGTCGCGGCGGCGGCCGGCAATCGCGCGGCGATCAACATGACCGGCGG
CGAGGCAATGCTCAATCTCGACACCATGCCGGCCGTGGTGTTCACCGATCCGCAGGTGGCCACCGTCGGCTTCAGCGAAG
CGGAAGCGCACCAAGCCGGCCTCGAAACCGACAGCCGCACCTTGACCCTGGACAACGTGCCGCGCGCTCTGGCGAACTTT
GACACACGGGGGTTCATCAAGCTGGTCGCCGAAACGGGCTCGGGCCGACTGCTGGGCGTGCAGGCAGTGACCCCGGAAGC
GGGCGAGCTGATTCAGACGGCCGCCCTCGCCATCCGCGCCCGGATGACGGTGCAGGAACTAGCCGACCAATTGTTCCCCT
ACCTGACCATGGTCGAGGGCCTGAAGCTCGCGGCGCAAACCTTCAGTAAGGACGTGAAGCAATTGTCCTGCTGCGCCGGG
TAA

Protein sequence : 
MTELKIIGMTCASCVVHVKEALEKIPGVHRADVSYASGRAELKVDEAVSREQMQAAVEALGYRAAFEDITLPTRPGLLDK
ARGWLSGGTDAGKEGDRLHVAVIGSGGAAMAAALKAVERGARVTLIERGIIGGTCVNVGCVPSKIMIRAAHVAHLRRESP
FDGGLPATPPLVLRERLLAQQQGRVDELRHAKYEGILESTPAITVLRGSARFQDSHTLSVELVEGGERIVTFDRCLIATG
ASAAVPPIPGLQDTPFWNSEKALASSSIPQRLAVIGSSVVALELAQAFARLGSRVTILARNSLFFREDPAIGAALTAAFR
LEGIEVLEQTQASQVAHANGEFVLTTKHGEVRVDQLLVATGRTPNTHGLNLEAAGVQLDERGAIQIDQGMRSSKADIYAA
GDCTNQPQFVYVAAAAGNRAAINMTGGEAMLNLDTMPAVVFTDPQVATVGFSEAEAHQAGLETDSRTLTLDNVPRALANF
DTRGFIKLVAETGSGRLLGVQAVTPEAGELIQTAALAIRARMTVQELADQLFPYLTMVEGLKLAAQTFSKDVKQLSCCAG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed ABR13401.1 mercuric reductase Not tested PAGI-5 Protein 0.0 100
merA ABQ57371.1 MerA Not tested SGI1 Protein 0.0 77
merA AGK07021.1 MerA Not tested SGI1 Protein 0.0 77
merA AGK07079.1 MerA Not tested SGI1 Protein 0.0 77
merA AAN62178.1 mercuric (Hg(II)) reductase Not tested PAGI-2(C) Protein 0.0 77
merA AET25397.1 MerA Not tested PAGI-2(C) Protein 0.0 76
merA AFG30120.1 MerA Not tested PAGI-2 Protein 0.0 76
merA YP_006098387.1 mercuric ion reductase Not tested Tn2411 Protein 0.0 76
merA ACN81005.1 MerA Hg(II) mercuric ion reductase Not tested AbaR5 Protein 0.0 76
merA CAJ77060.1 Mercuric ion reductase Not tested AbaR1 Protein 0.0 76

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
merA2 YP_001345486.1 putative mercuric reductase BAC0652 Protein 0.0 76
merA2 YP_001345486.1 putative mercuric reductase BAC0653 Protein 0.0 74
merA2 YP_001345486.1 putative mercuric reductase BAC0650 Protein 2e-180 71