Gene Information

Name : betB (PSPA7_6158)
Accession : YP_001351469.1
Strain : Pseudomonas aeruginosa PA7
Genome accession: NC_009656
Putative virulence/resistance : Virulence
Product : betaine aldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : 1.2.1.8
Position : 6363057 - 6364529 bp
Length : 1473 bp
Strand : -
Note : catalyzes the formation of betaine from betaine aldehyde

DNA sequence :
ATGGCCCGATTCGAAGAACAGAAGCTCTACATTGGCGGTCGCTACGTGGAGGCCAGCAGTGGCGCCACCTTCGAGACCAT
CAACCCGGCCAATGGCGAAGTGCTCGCCAAGGTCCAGCGGGCTTCCAGGGAAGACGTCGAGCGGGCCGTGCAGAGCGCCG
TCGAAGGGCAGAAGGTCTGGGCGGCGATGACCGCCATGCAACGCTCGCGCATCCTCCGTCGCGCCGTCGACCTCCTCCGC
GAGCGCAACGACGAACTGGCCGCCCTGGAAACCCTGGATACCGGCAAGCCGCTGGCGGAAACCCGCGCGGTGGACATCGT
CACCGGCGCCGACGTGCTCGAGTACTACGCGGGCCTGGTCCCGGCCATCGAAGGCGAGCAGATTCCGCTGCGCGAAACCA
GTTTCGTCTACACCCGCCGCGAGCCGCTGGGTGTGGTCGCCGGCATCGGCGCCTGGAACTACCCGGTGCAGATCGCCCTG
TGGAAATCAGCCCCGGCCCTCGCTGCCGGCAACGCGATGATCTTCAAGCCCAGCGAGGTCACCCCGCTGACCGCCCTCAA
GCTGGCCGAGATCTACACCGAGGCCGGCGTGCCGGACGGCGTGTTCAACGTGCTCACCGGCAGCGGACGCGAAGTCGGCC
AGTGGCTGACCGAGCACCCGCTGATCGAGAAGATCTCCTTCACCGGCGGCACCTCCACCGGCAAGAAGGTCATGGCCAGC
GCCTCCAGCTCGTCGCTGAAGGAAGTGACCATGGAACTGGGCGGAAAGTCCCCGCTGATCATCTTCCCCGACGCCGACCT
CGACCGCGCCGCCGACATCGCCGTCATGGCCAACTTCTTCAGCTCCGGCCAGGTCTGCACCAACGGCACCCGGGTATTCA
TCCACCGTTCCCAGCAGGCCCGCTTCGAAGCCAAGGTACTGGAGCGCGTGCAGCGCATCCGTCTTGGCGATCCGCAGGAC
GAGAACACCAACTTCGGCCCGCTGGTCAGCTTCCCGCACATGGAAAGCGTGCTCGGCTACATCGAGTCCGGCAAGGCGCA
GAAGGCTCGCCTGCTGTGCGGCGGCGAACGGGTGACCGAGGGGGCGTTCGGCAATGGCGCCTACGTCGCGCCGACCGTGT
TCACCGATTGCAGCGACGACATGACCATCGTCCGCGAGGAAATCTTCGGACCGGTGATGAGCATTCTGGTCTACGACGAC
GAGGACGAGGCGATCCGCCGCGCCAACGACACCGAGTACGGCCTCGCCGCCGGCGTCGTGACCCAGGACCTGGCCCGCGC
CCACCGCGCCATCCATCGCCTGGAAGCCGGCATCTGCTGGATCAATACCTGGGGCGAGTCGCCGGCGGAAATGCCGGTCG
GCGGTTACAAGCAATCCGGTGTCGGTCGCGAGAACGGCCTGACCACCCTGGCTCACTACACTCGCATCAAGTCCGTGCAA
GTGGAGCTGGGCGACTACGCCTCGGTGTTCTGA

Protein sequence :
MARFEEQKLYIGGRYVEASSGATFETINPANGEVLAKVQRASREDVERAVQSAVEGQKVWAAMTAMQRSRILRRAVDLLR
ERNDELAALETLDTGKPLAETRAVDIVTGADVLEYYAGLVPAIEGEQIPLRETSFVYTRREPLGVVAGIGAWNYPVQIAL
WKSAPALAAGNAMIFKPSEVTPLTALKLAEIYTEAGVPDGVFNVLTGSGREVGQWLTEHPLIEKISFTGGTSTGKKVMAS
ASSSSLKEVTMELGGKSPLIIFPDADLDRAADIAVMANFFSSGQVCTNGTRVFIHRSQQARFEAKVLERVQRIRLGDPQD
ENTNFGPLVSFPHMESVLGYIESGKAQKARLLCGGERVTEGAFGNGAYVAPTVFTDCSDDMTIVREEIFGPVMSILVYDD
EDEAIRRANDTEYGLAAGVVTQDLARAHRAIHRLEAGICWINTWGESPAEMPVGGYKQSGVGRENGLTTLAHYTRIKSVQ
VELGDYASVF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hpaE AAO17179.1 HpaE Not tested tcd island Protein 5e-77 42
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 2e-77 42
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 2e-77 42
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 2e-77 42
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 3e-77 42
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 3e-75 41
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 4e-81 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
betB YP_001351469.1 betaine aldehyde dehydrogenase VFG0082 Protein 1e-75 41