Gene Information

Name : dadX (PSPA7_6076)
Accession : YP_001351392.1
Strain : Pseudomonas aeruginosa PA7
Genome accession: NC_009656
Putative virulence/resistance : Unknown
Product : alanine racemase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0787
EC number : 5.1.1.1
Position : 6284806 - 6285912 bp
Length : 1107 bp
Strand : -
Note : catabolic enzyme, converts L-alanine to D-alanine which is then oxidized to pyruvate by dadA

DNA sequence :
ATGCCGCACCGCGCTGAAGAGAGACCCGTCGCCATGCGCCCCGCCCGTGCCCTGATCGACCTGCAAGCCCTTCGTCACAA
CTATCGCCTGGCCCGCGAGGCCACCGGCGCCCGCGCGCTCGCGGTGATCAAGGCGGACGCCTACGGGCATGGCGCGGTGC
GCTGTGCCGAAGCGCTGGCCGGGGAGGCGGATGGCTTCGCCGTGGCCTGCATCGAGGAAGCCCTGGAGTTGCGCGCGGCC
GGCATCCGCGAGCCGATTCTGCTGCTGGAAGGGTTCTTCGAGGCCGCCGAACTAGAATTGATCGTCGCCCATGATTTCTG
GTGCGTGGTGCATGCCGCCTGGCAACTGGAGGCGATCGAGCGCGCCAGCCTGGCGCGGCTGCTGACCGTCTGGCTGAAGA
TGGATTCGGGCATGCACCGCGTCGGCTTCTTCCCCGAGGACTTCCGCGCCGCCCACGAGCGCCTGCGGGCCAGCGGCAAG
GTGGCGAAGATCGTGATGATGAGCCACTTCTCCCGCGCCGACGAACTGGATTGCCCGCGCACCGATGAACAGCTCGCCGC
CTTCGCGGCCGCGAGCCAGGGCCTGGAAGGCGAGATCAGCCTGCGCAACTCGCCGGCCGTGCTCGGTTGGCCGAAGGTGC
CCAGCGACTGGGTACGTCCGGGTATCCTGCTCTACGGAGCCACGCCGTTCGAGCGTGCACATCCGCTGGCCGACCGCCTG
CGCCCGGTGATGACCCTGGAATCGAAGGTGATCAGCGTCCGCGAGCTGCCGGCCGGCGAACCGGTCGGCTACGGCGCGCG
CTACAGCACCGAGCGCAGCCAGCGCATCGGCGTGGTCGCGATGGGCTATGCCGACGGTTATCCGCGCCACGCGCCGGACG
GCACCCTGGTGTTCATCGACGGCAAGCCGGGGCGCCTGGTCGGCCGGGTGTCGATGGACATGCTCACCGTCGACCTTACC
GACCATCCACAGGCCGGGCTGGGCAGCCGGGTCGAATTGTGGGGGCCGAACGTCCCGGTGGGCGCCCTGGCGGCGCAGTT
CGGCAGCATTCCCTACCAGCTGCTGTGCAACCTGAAAAGAGTGCCGCGCGTCTATTCCGGGGCTTGA

Protein sequence :
MPHRAEERPVAMRPARALIDLQALRHNYRLAREATGARALAVIKADAYGHGAVRCAEALAGEADGFAVACIEEALELRAA
GIREPILLLEGFFEAAELELIVAHDFWCVVHAAWQLEAIERASLARLLTVWLKMDSGMHRVGFFPEDFRAAHERLRASGK
VAKIVMMSHFSRADELDCPRTDEQLAAFAAASQGLEGEISLRNSPAVLGWPKVPSDWVRPGILLYGATPFERAHPLADRL
RPVMTLESKVISVRELPAGEPVGYGARYSTERSQRIGVVAMGYADGYPRHAPDGTLVFIDGKPGRLVGRVSMDMLTVDLT
DHPQAGLGSRVELWGPNVPVGALAAQFGSIPYQLLCNLKRVPRVYSGA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
dadX AAC61705.1 alanine racemase Not tested PAI I CFT073 Protein 7e-61 49