Gene Information

Name : hemC (PSPA7_6006)
Accession : YP_001351322.1
Strain : Pseudomonas aeruginosa PA7
Genome accession: NC_009656
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 6203610 - 6204551 bp
Length : 942 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGTCGTCCCGCGAAATCCGCATCGCCACCCGCCAGAGCGCCCTCGCCTTGTGGCAGGCCGAATACGTCAAGGCGCGCCT
GGAACAGGCCCATCCCGACCTGACCGTCACCCTGCTGCCGATGACCAGTCGCGGCGACAAGCTGCTCGACGCGCCGCTGG
CGAAGATCGGCGGCAAGGGCCTGTTCGTCAAGGAGCTGGAGACCGCCCTGCTCGAGGGCGCCGCCGACATCGCGGTGCAC
TCGATGAAGGACGTGCCGATGGACTTCCCCGAAGGCCTTGGCCTCTACACCATCTGCGAGCGCGAAGACCCGCGTGACGC
CTTCGTCTCGAACACCTACGCGAGCCTCGACCAACTGCCCGCCGGCAGCGTGGTCGGCACCTCCAGCCTGCGCCGCCAGG
CGCAACTGCTGGCGCGCCGGCCGGACCTGCAGATCCGCTTCCTGCGTGGCAACGTCAACACCCGCCTGGCCAAGCTGGAT
GCCGGCGAGTACGACGCGATCATCCTCGCCGCCGCCGGCCTGATCCGCCTCGGCTTCGAGTCGCGCATCCGTTCCTCGAT
CAGCGTCGACGACAGCCTGCCCGCCGGTGGCCAGGGCGCGGTCGGCATCGAGTGCCGCACCGCCGACGCCGACCTGCACG
CCCTGCTGGCGCCCCTGCACCACGCCGATACGGCGCTGCGGGTCACTGCCGAGCGCGCGCTGAACAAGCGCCTCAACGGT
GGCTGCCAGGTGCCGATCGCCTGCTACGCGATTCGCGAGGGTGACCAACTGTGGCTGCGCGGCCTGGTCGGCCAGCCTGA
CGGCAGCCAGTTGCTGCGGGCCGAAGGGCGGGCGCCCCTGGCGCAGGCCGAGGCGCTGGGCGTACAGGTGGCCGACGACC
TCCTGGCGCAGGGCGCCGAGGCGATCCTCGCAGCGGTCTATGGCGAGGCTGGGCATCCGTGA

Protein sequence :
MSSREIRIATRQSALALWQAEYVKARLEQAHPDLTVTLLPMTSRGDKLLDAPLAKIGGKGLFVKELETALLEGAADIAVH
SMKDVPMDFPEGLGLYTICEREDPRDAFVSNTYASLDQLPAGSVVGTSSLRRQAQLLARRPDLQIRFLRGNVNTRLAKLD
AGEYDAIILAAAGLIRLGFESRIRSSISVDDSLPAGGQGAVGIECRTADADLHALLAPLHHADTALRVTAERALNKRLNG
GCQVPIACYAIREGDQLWLRGLVGQPDGSQLLRAEGRAPLAQAEALGVQVADDLLAQGAEAILAAVYGEAGHP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 6e-61 61
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 6e-61 61