Gene Information

Name : thiC (PSPA7_5702)
Accession : YP_001351021.1
Strain : Pseudomonas aeruginosa PA7
Genome accession: NC_009656
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 5870932 - 5872815 bp
Length : 1884 bp
Strand : -
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
ATGAGCGCAACGCAGAAGAACAACATCACCCGCCTTGAGCAGCTCGACCGCCAGTCGACGCAGCCTTTCCCGAACTCGCG
CAAGGTCTACCTGACCGGCTCGCGCCCGGACATACGCGTCCCGGTGCGGGAAATCTCCCTCGCCGACACCCCCACCGCCT
TCGGCGGCGAAAAGAACCCGCCGGTGTTCGTCTATGACACCTCCGGTCCGTATACCGACCCGGAGGTCCGCATCGACCTG
CGTAAGGGCCTGCCTGACGTGCGTTCGCGCTGGATCGACGAGCGCGGCGACACCGAGATCCTCCCCGGCCTGACTTCCGA
GTTCGGCCAGGCGCGCCTGGCCGACGCCAGCCTCGATGCGCTGCGCTTCGCCCACGTGCGCACGCCGCGCCGGGCCAAGC
CGGGCGCCAACGTCTCGCAGATGCATTACGCGAAGAAAGGCATCATCACCCCGGAGATGGAATACATCGCCATCCGCGAG
AACATGAAGCTGCAGGAAGCCCGGGCCGCCGGCCTGCTCGACCAGCAGCACCCGGGGCACAGCTTCGGCGCCAATATCCC
GAAGGAAATCACCCCCGAGTTCGTCCGCGAGGAAGTCGCCCGCGGCCGCGCGATCATTCCGGCGAACATCAACCACACCG
AGCTTGAGCCGATGATCATCGGCCGCAATTTTCTGGTGAAGATCAACGGCAACATCGGCAACAGCGCGCTGGGCTCGTCG
ATCGAGGAAGAAGTGGAGAAGCTCACCTGGGGCATCCGCTGGGGCGCTGACACGGTGATGGACCTGTCCACCGGCAAGCA
CATCCATGAAACCCGCGAGTGGATCCTGCGCAACAGCCCGGTACCGATCGGCACCGTACCGATCTACCAGGCGCTGGAAA
AGGTCAATGGCGTCGCCGAGGACCTGACCTGGGAAATCTTCCGCGACACCCTGATCGAACAGGCCGAGCAGGGCGTCGAC
TACTTCACCATCCACGCCGGCGTGCTGCTGCGCTATGTGCCGCTGACCGCCAAGCGGGTCACCGGCATCGTTTCCCGCGG
CGGCTCGATCATGGCCAAGTGGTGCCTGGCGCACCACAAGGAAAACTTCCTCTACACGCATTTCGAAGAGATCTGCGAAA
TCATGAAGGCCTACGACGTCAGCTTCTCGCTGGGCGATGGCCTGCGCCCGGGCTCGGTGGCCGACGCCAACGACGCCGCC
CAGTTCGGTGAGCTGGAGACCCTCGGCGAGCTGACCAAGATCGCCTGGAAGCACGACGTGCAGGTGATGATCGAAGGCCC
CGGCCACGTGCCGATGCAACTGATCAAGGAAAACATGGACAAGCAGCTGGAGTGCTGCGACGAGGCGCCGTTCTACACCC
TCGGTCCGCTGACCACCGACATCGCTCCCGGCTACGACCACATCACCTCGGGCATCGGCGCGGCGATGATCGGCTGGTTC
GGCTGCGCCATGCTCTGCTACGTCACGCCCAAGGAGCACCTGGGCCTGCCGAACAAGGATGACGTGAAGACCGGGATCAT
CACCTACAAGATCGCCGCCCACGCCGCCGACCTCGCCAAGGGCCACCCGGGCGCGCAGATCCGCGACAATGCGCTGTCCA
AGGCGCGCTTCGAGTTCCGCTGGGAAGACCAGTTCAACCTCGGCCTGGACCCGGACACCGCGCGGGCGTTCCATGACGAG
ACGCTGCCGAAGGACTCGGCCAAGGTCGCGCACTTCTGCTCCATGTGCGGACCGAAGTTCTGCTCGATGAAGATCACCCA
GGAAGTCCGCGACTACGCCAAGGAGAACGGCCTGTCCGACGAGAGCAAGGCCATCGAGGCCGGCTTCCAGGAGCAGGCGG
CGCGCTTCAAGGATGAAGGTTCGGTGATCTACAAGCAGGTGTAG

Protein sequence :
MSATQKNNITRLEQLDRQSTQPFPNSRKVYLTGSRPDIRVPVREISLADTPTAFGGEKNPPVFVYDTSGPYTDPEVRIDL
RKGLPDVRSRWIDERGDTEILPGLTSEFGQARLADASLDALRFAHVRTPRRAKPGANVSQMHYAKKGIITPEMEYIAIRE
NMKLQEARAAGLLDQQHPGHSFGANIPKEITPEFVREEVARGRAIIPANINHTELEPMIIGRNFLVKINGNIGNSALGSS
IEEEVEKLTWGIRWGADTVMDLSTGKHIHETREWILRNSPVPIGTVPIYQALEKVNGVAEDLTWEIFRDTLIEQAEQGVD
YFTIHAGVLLRYVPLTAKRVTGIVSRGGSIMAKWCLAHHKENFLYTHFEEICEIMKAYDVSFSLGDGLRPGSVADANDAA
QFGELETLGELTKIAWKHDVQVMIEGPGHVPMQLIKENMDKQLECCDEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWF
GCAMLCYVTPKEHLGLPNKDDVKTGIITYKIAAHAADLAKGHPGAQIRDNALSKARFEFRWEDQFNLGLDPDTARAFHDE
TLPKDSAKVAHFCSMCGPKFCSMKITQEVRDYAKENGLSDESKAIEAGFQEQAARFKDEGSVIYKQV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 0.0 78
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 0.0 78
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 0.0 74