Gene Information

Name : smpB (PSPA7_5488)
Accession : YP_001350810.1
Strain : Pseudomonas aeruginosa PA7
Genome accession: NC_009656
Putative virulence/resistance : Unknown
Product : SsrA-binding protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0691
EC number : -
Position : 5655845 - 5656324 bp
Length : 480 bp
Strand : +
Note : binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Ca

DNA sequence :
ATGGCTAAGCAGAAGAAACACCCTTCGGGGACCATCGCGCAGAACAAGAAGGCTCTGCACGACTACTTCATCGAACAACG
CTTCGAGGCGGGCGTCGCCCTGGCGGGCTGGGAAGTGAAAAGCCTGCGCGCCGGCAAGGCCCAGCTGGTCGACAGCTACG
TGCTGCTCAAGGACGGCGAGGCCTGGCTGCTCGGCAGCCACATCACGCCGCTGACGACCGCCAGCACGCACGTGATCGCC
GACCCGGTGCGCACGCGCAAGTTGCTGCTGCACAAGCGCGAACTGGGCAAGCTGTTCGGTGCCGTGCAACAGAAGGGCTA
CGCCTGCGTTGCCCTGTCGATGTACTGGAAGAAGCACCTGGTCAAGTGCGAGATCGCCCTGGCCAAGGGCAAGAAGGACT
TCGACAAGCGCCACACCGAGAAGGAGCGCGACTCCGACCGGGAGATCCAGCGCGCCATGCGCCACGGCAAGGACGACTGA

Protein sequence :
MAKQKKHPSGTIAQNKKALHDYFIEQRFEAGVALAGWEVKSLRAGKAQLVDSYVLLKDGEAWLLGSHITPLTTASTHVIA
DPVRTRKLLLHKRELGKLFGAVQQKGYACVALSMYWKKHLVKCEIALAKGKKDFDKRHTEKERDSDREIQRAMRHGKDD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
smpB NP_230495.1 SsrA-binding protein Not tested VPI-1 Protein 5e-35 55
smpB YP_001800894.1 SsrA-binding protein Not tested Not named Protein 3e-25 46
unnamed AET14351.1 SsrA-binding protein Not tested SaPI68111 Protein 7e-25 45