Gene Information

Name : pilR (PSPA7_5187)
Accession : YP_001350519.1
Strain : Pseudomonas aeruginosa PA7
Genome accession: NC_009656
Putative virulence/resistance : Virulence
Product : two-component response regulator PilR
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG2204
EC number : -
Position : 5333784 - 5335121 bp
Length : 1338 bp
Strand : +
Note : Annotation generated by automatically transferring the annotation from the manually curated GenBank accession AE004091; identified by match to protein family HMM PF00072; match to protein family HMM PF00158; match to protein family HMM PF02954

DNA sequence : 
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAGCTGCTGGAAATCACCCTCGGCCGCATGAA
GCTGGATACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAACCGTTCGACCTGTGCCTGACCG
ACATGCGCCTGCCGGACGGTAGCGGCCTCGACCTGGTGCAGTACATCCAGCAGCGTCACCCGCAAACTCCGGTCGCCATG
ATCACCGCCTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGCGCCTTCGACTTCCTCACCAAGCCGGTCGA
CCTCGGCCGCCTGCGCGAACTGGTGGCGACCGCCCTGCGCCTGCGCCATCCGGAAACCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCTCCGCCGATGCGCGCGCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGCGGCGAGTCCGGCAGCGGCAAGGAACTGGTGGCCCGCCTGATCCACGAGCAGGGGCCGCGCATCGAGCGACCGTT
CGTGCCGGTCAACTGCGGCGCGATCCCTACCGAGCTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACCG
GCGCCATCGAGGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGCGGTACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGCCGATGCAGGTCAAGCTGCTCCGCGCAATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGATCGGCGT
CGACGTCCGCATCCTCTGCGCCACCCACAAGGACCTCGCCGCCGAGGTCGGCGCCGGGCGCTTCCGCCAGGATCTCTACT
ACCGCCTCAACGTCATCGAATTGCGCGTTCCGCCCCTGCGCGAACGCCGCGAGGACATCCCGCTGCTGGCCGAGCGCATC
CTCAAGCGCCTGGCCGGCGATACCGGCTTGCCAGCCGCCCGCCTGACCGGCGATGCCCAGGAAAAGCTGAAGAACTATCG
CTTCCCCGGCAACGTGCGTGAACTGGAGAACATGCTGGAGCGCGCCTACACGCTGTGCGAGAACGACCAGATCCAGCCCC
ACGACCTGCGCGTGGCCGACGCGCCGGGCGCCAGCCAGGACGGCGCGGCGAGCCTGAGCGAGATAGACAATCTCGAGGAC
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAGGCTCTCGAGGAGACCCGCTGGAACCGCACTGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGTTCGATGCGTTATCGCCTGAAGAAACTCGGCATAGATTGA

Protein sequence : 
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRHPETEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPTELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MPMQVKLLRAIQEKAVRAVGGQQEIGVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLAERI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCENDQIQPHDLRVADAPGASQDGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00300 YP_008207765.1 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Not tested AbaR25 Protein 3e-103 51
BJAB0868_00304 YP_008211630.1 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Not tested AbaR26 Protein 3e-103 51

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pilR YP_001350519.1 two-component response regulator PilR BAC0089 Protein 9e-73 45
pilR YP_001350519.1 two-component response regulator PilR BAC0467 Protein 1e-72 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pilR YP_001350519.1 two-component response regulator PilR VFG1214 Protein 0.0 98
pilR YP_001350519.1 two-component response regulator PilR VFG0116 Protein 1e-57 43
pilR YP_001350519.1 two-component response regulator PilR VFG1249 Protein 1e-68 41