Gene Information

Name : lpdA2 (PSPA7_2991)
Accession : YP_001348351.1
Strain : Pseudomonas aeruginosa PA7
Genome accession: NC_009656
Putative virulence/resistance : Unknown
Product : dihydrolipoamide dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1249
EC number : 1.8.1.4
Position : 3081622 - 3083016 bp
Length : 1395 bp
Strand : -
Note : E3 component of the branched-chain alpha-keto acid dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide

DNA sequence :
ATGAGCCAGACCCTGAAGACTACCCTGCTGATCGTCGGCGGCGGTCCCGGCGGCTACGTCGCGGCGATCCGTGCCGGGCA
GTTGGGCATTCCCACCGTGCTGGTGGAGGGCGCCGCCCTCGGCGGCACCTGCCTGAACGTCGGCTGCATCCCGTCGAAGG
CGCTGATCCACGCCGCCGAGGAATACCTCAAGGCCCGCCACTATGCCGGCCAGTCGGCGCTGGGCATCCAGGTACAGGCG
CCGAGCATCGACATCGCCCGCACCGTGGAGTGGAAGGACGCCATCGTCGACCGTCTCACCAGCGGCGTTGCCGCGCTGCT
GAAGAAGCACGGGGTCACTGTCGTCCAGGGCTGGGCAAGAATCCTCGACGGCAAGAGCGTGGCGGTCGAACTGGCCGGCG
GCGGCAGCCAGCGCATCGACTGCGAGCACCTGCTGCTGGCCGCCGGCTCGCAGAGCGTCGAGCTGCCGAGCCTGCCGCTG
GGCGGCAAGGTGATCTCCTCCACCGAGGCGCTGGCGCCCGGCAGCCTGCCCGGGCGCCTGGTGGTGGTCGGCGGCGGCTA
CATCGGCCTGGAGCTGGGTACCGCCTACCGCAAGCTCGGCGTCGAGGTCGCGGTGGTGGAGGCGCAACCGCGCATCCTGC
CGGGCTACGACGAGGAACTGACCAAGCCGGTGGCCCAGGCCCTGCGCAAGCTGGGCGTCGAGCTGTATCTCGGGCACAGC
CTGCTGGGCCCGGGCGAGAATGGCGTACGGGTCCGCGACGGCGCCGGCGAGGAGCGCGAGATCGCCGCCGACCAGGTGCT
GGTGGCGGTCGGCCGCAGACCGCGCAGCGAAGGCTGGAACCTGGAAAGCCTGGGCCTGGACATGAACGGCCGGGCGGTGA
AGGTCGACGACCAGTGCCGCACCTCGATGCGCAATGTCTGGGCCATCGGCGACCTCGCCGGCGAGCCGATGCTGGCGCAC
CGGGCCATGGCCCAGGGCGAGATGGTCGCCGAGCTGATCGCCGGCAGGCGCCGCCAGTTCGCCCCGCTGGCGATCCCGGC
GGTGTGCTTCACCGATCCGGAAGTGGTGGTCGCCGGGCTGTCCCCCGAGCAGGCGAAGGATGCCGGGCTGGACTGCCTGG
TGGCGAGCTTCCCGTTCGCCGCCAACGGCCGCGCCATGACCCTGGAGGCCAACGAAGGCTTCGTCCGCGTGGTGGCGCGC
CGCGACAACCATCTGGTCGTCGGCTGGCAGGCGGTGGGCAAGGCGGTCTCGGAGCTGTCCACGGCCTTCGCCCAGTCGCT
GGAGATGGGCGCCCGCCTGGAAGACATCGCCGGCACCATCCACGCCCACCCGACCCTCGGCGAAGCGGTCCAGGAAGCCG
CCCTGCGCGCGCTGGGGCACGCCCTGCACATCTGA

Protein sequence :
MSQTLKTTLLIVGGGPGGYVAAIRAGQLGIPTVLVEGAALGGTCLNVGCIPSKALIHAAEEYLKARHYAGQSALGIQVQA
PSIDIARTVEWKDAIVDRLTSGVAALLKKHGVTVVQGWARILDGKSVAVELAGGGSQRIDCEHLLLAAGSQSVELPSLPL
GGKVISSTEALAPGSLPGRLVVVGGGYIGLELGTAYRKLGVEVAVVEAQPRILPGYDEELTKPVAQALRKLGVELYLGHS
LLGPGENGVRVRDGAGEEREIAADQVLVAVGRRPRSEGWNLESLGLDMNGRAVKVDDQCRTSMRNVWAIGDLAGEPMLAH
RAMAQGEMVAELIAGRRRQFAPLAIPAVCFTDPEVVVAGLSPEQAKDAGLDCLVASFPFAANGRAMTLEANEGFVRVVAR
RDNHLVVGWQAVGKAVSELSTAFAQSLEMGARLEDIAGTIHAHPTLGEAVQEAALRALGHALHI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SE0077 NP_763632.1 dihydrolipoamide dehydrogenase component of pyruvate dehydrogenase E3 Not tested SCCpbp4 Protein 3e-81 44