Gene Information

Name : arsB (PSPA7_2963)
Accession : YP_001348323.1
Strain : Pseudomonas aeruginosa PA7
Genome accession: NC_009656
Putative virulence/resistance : Resistance
Product : arsenite-antimonite efflux pump ArsB
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG1055
EC number : -
Position : 3051670 - 3052953 bp
Length : 1284 bp
Strand : -
Note : Annotation generated by automatically transferring the annotation from the manually curated GenBank accession AE004091; identified by match to protein family HMM PF02040; match to protein family HMM PF03600; match to protein family HMM TIGR00935

DNA sequence :
ATGCTGATCGCCTTCGCCATCTTCCTGTTCACCCTGGTCCTGGTCATCTGGCAACCCAGGGGCCTCGGCATCGGCTGGAG
CGCCAGCATCGGCGCGCTGCTCGCCCTGGCCCTGGGCAGCGTCGCGCCGGGCGACATCCCGACCGTCTGGAACATCGTCT
GGAATGCCACCGCCACCTTCATCGCGGTGATCGTCATCAGCCTGCTGCTGGACGAGGCCGGCTTCTTCGAATGGGCCGCG
CTGCACGTCGCGCGCTGGGCCGGCGGCGACGGCCGGCGCCTGTTCGCCTTCTGCGTGCTGCTCGGCGCGGCGGTCTCGGC
GCTGTTCGCCAACGACGGCGCGGCGCTGATCCTCACGCCTATCGTGATGTCGATGCTGCTGGCCCTGCGCTTCAGCCCGG
CGGCGACCCTGGCCTTCGTCATGGCGGCAGGCTTCATCGCCGACAGCGCCAGCCTGCCGCTGGTGGTGTCGAACCTGGTG
AACATCGTCTCGGCCGACTACTTCGGGCTCGGCTTCGGCGAGTACGCCGCGGTGATGCTGCCGGTCAACCTGGTGAGCGT
CGCGACCTCCCTGCTGGTGCTGTTCCTGTATTTCCGCCGCGACCTGCCGCCGGTCTATGCGCTGGAGCAATTGAAGCCGC
CGCGGGCGGCGATCCGCGACCGTGCGACCTTCGTCGTCGGCGGCTGGATGCTGCTGGTCCTGCTCGCCGGGCTGTTCGCC
CTGGAGCCGCTGGGCGTCCCCGTCAGCGCGGTGGCCGCGGCCTGCGCGGCGCTGCTACTGGCGGTGGCCGGGCGCGGGCG
GGTGATCTCGACCCGGCGGGTGCTGCGCGAAGCGCCCTGGCAGATCGTGGTGTTCTCGCTGGGCATGTACCTGGTGGTCT
ACGGCCTGAAGAACGCCGGGCTCACCGACCTCCTGGCGCAGTTCCTGGACCGCCTGGCCGGACACGGCGTATGGGTGGCC
GCGCTGGGCACCGGGCTGCTTTCCGCCGCGCTCTCCTCGGTGATGAACAACATGCCCAGCGTGCTGCTCGGCGCCCTGTC
GATCCAGGCCAGCGACGCCGCCGGCGCGGTGCGCGAAGCGATGATCTACGCCAACGTCATCGGCTGCGACCTGGGGCCGA
AGATCACCCCTATCGGCAGCCTGGCGACGCTGCTCTGGCTGCACGTGCTGGCGCGCAAAGGCACGCGCATCACCTGGGGC
TACTACTTCAGGGTCGGCGCCCTGCTGACCCTGCCGGTCCTGCTGGCGACCCTTTCGGCCCTGGCCCTGCGCCTGAGCCT
CTGA

Protein sequence :
MLIAFAIFLFTLVLVIWQPRGLGIGWSASIGALLALALGSVAPGDIPTVWNIVWNATATFIAVIVISLLLDEAGFFEWAA
LHVARWAGGDGRRLFAFCVLLGAAVSALFANDGAALILTPIVMSMLLALRFSPAATLAFVMAAGFIADSASLPLVVSNLV
NIVSADYFGLGFGEYAAVMLPVNLVSVATSLLVLFLYFRRDLPPVYALEQLKPPRAAIRDRATFVVGGWMLLVLLAGLFA
LEPLGVPVSAVAAACAALLLAVAGRGRVISTRRVLREAPWQIVVFSLGMYLVVYGLKNAGLTDLLAQFLDRLAGHGVWVA
ALGTGLLSAALSSVMNNMPSVLLGALSIQASDAAGAVREAMIYANVIGCDLGPKITPIGSLATLLWLHVLARKGTRITWG
YYFRVGALLTLPVLLATLSALALRLSL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
arsB2 YP_001007633.1 arsenical pump membrane protein Not tested YAPI Protein 2e-109 70
arsB YP_252017.1 arsenical pump membrane protein Not tested SCCmec Protein 1e-86 54
arsB YP_005754065.1 arsenical pump membrane protein Not tested Type-XI SCCmec Protein 5e-85 53
SH0109 YP_252024.1 arsenical pump membrane protein Not tested SCCmec Protein 7e-87 53

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
arsB YP_001348323.1 arsenite-antimonite efflux pump ArsB BAC0576 Protein 2e-110 71
arsB YP_001348323.1 arsenite-antimonite efflux pump ArsB BAC0031 Protein 2e-111 71
arsB YP_001348323.1 arsenite-antimonite efflux pump ArsB BAC0578 Protein 1e-110 71
arsB YP_001348323.1 arsenite-antimonite efflux pump ArsB BAC0577 Protein 1e-105 70
arsB YP_001348323.1 arsenite-antimonite efflux pump ArsB BAC0575 Protein 2e-87 53
arsB YP_001348323.1 arsenite-antimonite efflux pump ArsB BAC0574 Protein 6e-87 53