Gene Information

Name : tpx (PSPA7_2704)
Accession : YP_001348064.1
Strain : Pseudomonas aeruginosa PA7
Genome accession: NC_009656
Putative virulence/resistance : Virulence
Product : thiol peroxidase
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG2077
EC number : -
Position : 2719784 - 2720281 bp
Length : 498 bp
Strand : +
Note : antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein

DNA sequence : 
ATGGCTCAAGTGACTCTCAAGGGCAACCCGGTCAACGTCGACGGCCAGCTTCCGCAGAAAGGCGCCCAGGCTCCGGCCTT
CAGCCTGGTCAGCGGCGACCTCGCCGACGTGACCCTGGAAAACTTCGCCGGCAAGCGCAAGGTGCTGAACATCTTCCCCA
GCGTCGACACTCCGACCTGCGCCACCTCGGTCCGCAAGTTCAACGTCGAGGCCGGCAAGCTGGCCAATACCGTGGTGCTG
TGCATCTCCGCCGACCTGCCGTTCGCGCAGAAGCGCTTCTGCGGCGCCGAGGGCCTGGAGAACGTGGTCAACCTGTCGAC
CCTGCGTGGCCGCGAGTTCCTCGAGAACTATGGCGTGGCCATCGCCAGCGGCCCGCTGGCCGGCCTGGCCGCGCGCGCCG
TGGTGGTGCTCGACGAGCAGGACAAGGTGCTGCACAGCGAGCTGGTCGGCGAGATCGCCGACGAGCCGAACTACGCGGCG
GCCCTGGCGGTTCTCTGA

Protein sequence : 
MAQVTLKGNPVNVDGQLPQKGAQAPAFSLVSGDLADVTLENFAGKRKVLNIFPSVDTPTCATSVRKFNVEAGKLANTVVL
CISADLPFAQKRFCGAEGLENVVNLSTLRGREFLENYGVAIASGPLAGLAARAVVVLDEQDKVLHSELVGEIADEPNYAA
ALAVL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tpx NP_230472.1 thiol peroxidase Virulence VPI-1 Protein 1e-28 47
tpx YP_001216305.1 thiol peroxidase Not tested VPI-1 Protein 1e-28 47
tagD AAK20781.1 toxR-activated gene D protein Virulence VPI Protein 7e-29 47
tagD AAK20751.1 toxR-activated gene D protein Virulence VPI Protein 7e-29 47

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
tpx YP_001348064.1 thiol peroxidase VFG0087 Protein 3e-29 47