Gene Information

Name : guaA (PSPA7_1347)
Accession : YP_001346731.1
Strain : Pseudomonas aeruginosa PA7
Genome accession: NC_009656
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 1359448 - 1361031 bp
Length : 1584 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGGCCATGTCCCAAGACATTCACGCCCACCGTATCCTGATCCTCGATTTCGGCTCCCAGTACACCCAGCTGATCGCCCG
CCGCGTGCGCGAGATCGGCGTGTACTGCGAAATCCATCCCTTCGACATGAGCGACGAGGCGATCATCGCCTTCGCCCCGC
GCGGCATCATCCTCGCCGGCGGTCCCGAGTCGGTGCACGAAGCCGACAGCCCGCGCGCGCCGCAGGCGGTGTTCGACCTG
AAGGTGCCGCTGTTCGGCATCTGCTACGGCATGCAGACCATGGCCGAGCAGATGGGCGGCAAGGTGCAGGGCTCCGACCT
GCGCGAGTTCGGCTACGCCCGCGTCGACGTGGTCGGCAAGGCGCGCCTGCTGGACGGTATCGAGGACCACGTGGACGACG
ACGGCGTGCTCGGCCTCGACGTGTGGATGAGTCACGGCGACAAGGTCACCGAGATGCCGGCCGGCTTCCACATCCTGGCC
AGCACCCCGAGCTGCCCGATCGCCGCCATGGCCGACGATGCCCGCGCCTACTACGGCGTGCAGTTCCATCCGGAAGTCAC
CCACACCAAGCAGGGCCTGCGCATTCTCTCGCGCTTCGTCCTCGACATCTGCGGCTGCGCCGCGCTGTGGACCCCATCGA
ACATCGTCGAGGACGCCATCGCCACCGTGCGCGCCCAGGTCGGTTCGTCCAAGGTCCTGCTCGGCCTCTCCGGCGGCGTG
GACTCCTCGGTGGTCGCCGCGCTGCTGCACAAGGCCATCGGCGACCAGCTGACCTGCGTGTTCGTCGACAACGGCCTGCT
GCGCCTGCACGAAGGCGACCAGGTGATGGCCATGTTCGCCGAGAACATGGGCGTGAAGGTGATCCGCGCCAACGCCGAGG
ACAAGTTCCTCGGTCGCCTGGCCGGCGTCGCCGACCCGGAAGAGAAGCGCAAGATCATCGGCCGCACCTTCATCGAAGTC
TTCGACGAAGAAGCCACCAAGCTGCAGGACGTGAAGTTCCTCGCCCAGGGCACCATCTACCCCGACGTGATCGAGTCGGC
TGGCGCCAAGACCGGCAAGGCCCACGTGATCAAGTCGCACCACAACGTCGGCGGCCTGCCGGAGGACATGCAGTTCGAAC
TGGTCGAGCCGCTGCGCGAGCTGTTCAAGGACGAAGTGCGCAAGATCGGCCTGGAGCTGGGCCTGCCCTACGACATGGTC
TACCGCCACCCGTTCCCCGGCCCGGGCCTGGGCGTGCGCATCCTCGGCGAAGTGAAGAAGGAATACGCCGACCTGCTGCG
CCAGGCCGACCACATCTTCATCGAGGAACTGCGTGCCTTCGACTGGTACCACAAGACCAGCCAGGCATTCGTGGTGTTCC
AGCCGGTGAAATCGGTCGGCGTGGTCGGCGACGGCCGCCGCTATGCCTGGGTCGTCGCCCTGCGCGCGGTGGAAACCATC
GACTTCATGACCGCGCGCTGGGCGCACCTGCCCTACGAGCTGCTGGAAAAGGTCTCGAACCGCATCATCAACGAGATCGC
CGGCATCTCCCGGGTCACCTACGACGTGTCGAGCAAGCCGCCGGCGACTATCGAGTGGGAATGA

Protein sequence :
MAMSQDIHAHRILILDFGSQYTQLIARRVREIGVYCEIHPFDMSDEAIIAFAPRGIILAGGPESVHEADSPRAPQAVFDL
KVPLFGICYGMQTMAEQMGGKVQGSDLREFGYARVDVVGKARLLDGIEDHVDDDGVLGLDVWMSHGDKVTEMPAGFHILA
STPSCPIAAMADDARAYYGVQFHPEVTHTKQGLRILSRFVLDICGCAALWTPSNIVEDAIATVRAQVGSSKVLLGLSGGV
DSSVVAALLHKAIGDQLTCVFVDNGLLRLHEGDQVMAMFAENMGVKVIRANAEDKFLGRLAGVADPEEKRKIIGRTFIEV
FDEEATKLQDVKFLAQGTIYPDVIESAGAKTGKAHVIKSHHNVGGLPEDMQFELVEPLRELFKDEVRKIGLELGLPYDMV
YRHPFPGPGLGVRILGEVKKEYADLLRQADHIFIEELRAFDWYHKTSQAFVVFQPVKSVGVVGDGRRYAWVVALRAVETI
DFMTARWAHLPYELLEKVSNRIINEIAGISRVTYDVSSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 8e-122 52
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 7e-122 52
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 6e-122 52
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-108 48