Gene Information

Name : leuS (PSPA7_1121)
Accession : YP_001346507.1
Strain : Pseudomonas aeruginosa PA7
Genome accession: NC_009656
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 1117515 - 1120136 bp
Length : 2622 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGCACGAGCAATATCAGCCACTCGAGATCGAAACCCAGGCCCAGAACTACTGGAAAGAACACCAGTCCTTCCTCGTCAG
GGAGCTACCCGACAAAGAGAAGTTCTACTGCCTGTCGATGTTCCCGTATCCGAGCGGCAAGCTGCACATGGGCCACGTGC
GCAACTACACCATCGGCGACGTGATCAGCCGCTACCACCGCATGCAGGGCCGCAACGTGCTGCAGCCGATGGGCTGGGAC
GCGTTCGGCATGCCGGCGGAAAACGCCGCGATGAAGAACAACGTAGCGCCGGCGGCCTGGACCTACGACAACATCGCCTA
CATGAAGTCGCAGCTGGACAGCCTCGGCCTGGCCATCGACTGGACCCGCGAAGTCACCACCTGCAAACCGGATTACTACC
GCTGGGAGCAGTGGTTGTTCACCCGCCTGTTCGAGAAAGGCGTGATCTACCGCAAGAACGGCACCGTGAACTGGGACCCG
GTCGACCAGACCGTACTCGCCAACGAGCAGGTGATCGACGGGCGCGGCTGGCGCTCCGGCGCGCTGATCGAGAAGCGCGA
GATCCCGATGTACTACTTCAAGATCACCGCCTACGCCGAGGAACTGCTGGAAAGCCTCGACAACCTGCCCGGCTGGCCGG
AGCAGGTGAAGACCATGCAGCGCAACTGGATCGGCAAGTCGCGCGGGATGGAGATCGCCTTCCCCTACGACCAGGCCTCG
ATCGGCCACGCCGGCCAGTTGAAGGTCTTCACCACCCGCCCGGACACGCTGATGGGCGCCACCTACGTGGCCGTCGCCGC
CGAGCATCCGCTGGCCACCCAGGCCGCGCAGAACGATCCGCAGTTGCAGGCATTCATCGACGAGTGCAAGCGCGGCGGCG
TCGCCGAGGCCGACATCGCCACCCAGGAAAAGAAAGGCCTGGCCACTTCCCTGTTCGTCGAACACCCGTTGACCGGCGAC
AAGCTGCCGGTGTGGGTCGCCAACTACGTGCTGATGAACTACGGCGAAGGCGCGGTGATGGCGGTGCCCGGCCATGACGA
ACGCGACTTCGAATTCGCCAACAAGTACGGCCTGCCGATCCGCCAGGTGATCGCCAGGGTCGAAGGCGAGAACGACTTCG
AGCCCACCGTATGGAAGGAATGGTACGGCGCCAAGGACGAGTCCGTGCGCACCGTCAACTCCGGCAAGTACGACGACCTC
GGCTACCAGGCCGCCTTCGACGCCATTGGCGCCGACCTCGAGGCCAAGGGCCTGGGCCAGGCGCGCACTCAGTTCCGCCT
GCGCGACTGGGGCATCAGCCGCCAGCGCTACTGGGGCTGTCCGATCCCGATCATCCATTGCGACGCTTGCGGCGACGTCC
CGGTGCCGGCCGAGCAGTTGCCGGTGGTCCTGCCGGAGGACGTGGTGCCGGACGGCGCCGGCTCGCCGCTGGCGAAGATG
CCGGAGTTCTACGAGTGCAGCTGCCCGAAGTGCGGCCAGCCGGCCAAGCGCGAAACCGACACCATGGACACCTTCGTCGA
GTCGTCCTGGTACTTCGCCCGCTACGCCTGCCCGCAGTTCGAAGGCGGCATGCTGGACAAGAAGGCCGCCGACTACTGGC
TGCCGGTCGACCAGTACATCGGTGGCATCGAGCACGCCATCCTGCACCTGCTCTACGCGCGCTTCTTCCACAAGCTGATG
CGCGACGAGGGGCTGGTCGGCAGCGACGAGCCGTTCAGGAACCTGCTGACCCAGGGCATGGTGGTTGCCGACACCTATTA
CCGGACCACCGCCAATGGCGGCAAGGACTGGTTCAACCCGGCCGACGTCGAGGTCGAGCGCGACGCCAAGGCCAAGGTGG
TCGGCGCGCGCCTGAAGAGCGACGGCCAGCCGGTGGAGATCGGCGGCACCGAGAAGATGTCGAAGTCGAAGAACAACGGC
GTCGACCCGCAATCGATGATCGACCAGTATGGCGCCGATACCTGCCGCCTGTTCATGATGTTCGCCTCGCCGCCGGACAT
GAGCCTGGAGTGGTCGGACGCCGGCGTCGAAGGCGCCAACCGCTTCCTCCGCCGCGTCTGGCGCCTGGCCCACGCGCACG
TCAGCGCCGGTCTCCCCGGCGCGCTGGACGGCGCCAGCCTGAGCGATGCGCAGAAGCAGGTGCGTCGCGCCATCCACCTG
GCGATCAGGCAGGCCAGCCAGGATGTCGGCCAGCACCACAAGTTCAACACCGCCATCGCCGCGGTGATGACCCTGATGAA
CGTGCTGGAGAAAGCACCGAGCCAGGACGCCCAGGATCGCGCGCTGCTCCAGGAGGGCCTGGAAACCGTGGTCCTGCTGC
TCGCGCCGATCACCCCGCATATCTGCCACGTGCTGTGGGAGCAGCTCGGCCACGCCGAGGCGGTGATCGACGCACGCTGG
CCGGTCGTCGACGAAAGCGCCCTGGTGCAGGACACCCTGCAACTGGTGGTGCAGGTCAACGGCAAGCTGCGCGGGCACAT
CGACGTGGCCGCCAGCGCCAGCCGCGAGGACGTCGAGGCGGCGGCGCGGGCCAACGAGAACGTGCTGCGCTTCACCGAGG
GACTGAGCATCCGCAAGGTCATCGTGGTTCCGGGCAAGCTGGTCAACATCGTCGCCAACTGA

Protein sequence :
MHEQYQPLEIETQAQNYWKEHQSFLVRELPDKEKFYCLSMFPYPSGKLHMGHVRNYTIGDVISRYHRMQGRNVLQPMGWD
AFGMPAENAAMKNNVAPAAWTYDNIAYMKSQLDSLGLAIDWTREVTTCKPDYYRWEQWLFTRLFEKGVIYRKNGTVNWDP
VDQTVLANEQVIDGRGWRSGALIEKREIPMYYFKITAYAEELLESLDNLPGWPEQVKTMQRNWIGKSRGMEIAFPYDQAS
IGHAGQLKVFTTRPDTLMGATYVAVAAEHPLATQAAQNDPQLQAFIDECKRGGVAEADIATQEKKGLATSLFVEHPLTGD
KLPVWVANYVLMNYGEGAVMAVPGHDERDFEFANKYGLPIRQVIARVEGENDFEPTVWKEWYGAKDESVRTVNSGKYDDL
GYQAAFDAIGADLEAKGLGQARTQFRLRDWGISRQRYWGCPIPIIHCDACGDVPVPAEQLPVVLPEDVVPDGAGSPLAKM
PEFYECSCPKCGQPAKRETDTMDTFVESSWYFARYACPQFEGGMLDKKAADYWLPVDQYIGGIEHAILHLLYARFFHKLM
RDEGLVGSDEPFRNLLTQGMVVADTYYRTTANGGKDWFNPADVEVERDAKAKVVGARLKSDGQPVEIGGTEKMSKSKNNG
VDPQSMIDQYGADTCRLFMMFASPPDMSLEWSDAGVEGANRFLRRVWRLAHAHVSAGLPGALDGASLSDAQKQVRRAIHL
AIRQASQDVGQHHKFNTAIAAVMTLMNVLEKAPSQDAQDRALLQEGLETVVLLLAPITPHICHVLWEQLGHAEAVIDARW
PVVDESALVQDTLQLVVQVNGKLRGHIDVAASASREDVEAAARANENVLRFTEGLSIRKVIVVPGKLVNIVAN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 1e-138 41