Gene Information

Name : leuS (Asuc_0743)
Accession : YP_001344050.1
Strain : Actinobacillus succinogenes 130Z
Genome accession: NC_009655
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : -
Position : 801324 - 803906 bp
Length : 2583 bp
Strand : +
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGCAAGAACAATATCGTCCCGATTTGATTGAAGCCGAAGTGCAAAAATATTGGCAAGAGAACAAAACCTTTAAAGCGAT
TAAAGATACCAATAAAGAAAAATATTATTGTCTTTCCATGTTGCCGTATCCTTCAGGCCGTCTGCACATGGGGCATGTGC
GTAATTACACTATCGGGGATGTGGTTTCCCGCTATCAGCGGATGATCGGAAAAAATGTGTTGCAACCGATGGGATGGGAT
GCATTCGGTCTTCCGGCGGAAGGGGCCGCGGTGAAAAACAATACCGCACCGGCGAAATGGACTTACGAAAATATCGAATA
CATGAAAAACCAGTTAAAGGTGCTGGGCTTTTCTTATGATTGGGAGCGCGAAGTCACTACTTGCCGTCCCGAATATTATA
AATGGGAACAATGGTTTTTCACCGAGCTTTATAAAAAAGGTTTAGTGTATAAAAAAACGTCGGTAGTGAACTGGTGTCCG
AACGATGAAACCGTACTTGCCAACGAGCAGGTTCACGAAGGCTGTTGCTGGCGTTGCGATACACCGGTGGAGCAACGGGA
AATTCCGCAATGGTTTATTAAAATAACCGATTATGCCGAACAATTATTAGGCGGTTTGGATACGCTTCCCGAATGGCCGG
AAATGGTAAAAACCATGCAACGCAACTGGATAGGTCGTTCCGAAGGGGTGGAAATCACCTTTAAAATTGAAAATTCGGAT
GAAACCGTAGCGGTTTATACCACCCGCCCGGACACTTTCTATGGGGTATCTTATATGGCGGTGGCGGCAGGTCATCCGCT
GGCGGAACGTGCGGCTCAAAATAATCCCGATTTAGCGAAATTTATTCAGGAATGCAAAAATACTAAAGTGGCGGAAGCGG
AACTTGCCACCATGGAGAAAAAAGGGATGGCTACCGGCTTGAACGCCGTTCATCCGATTACTGGTAAACCGGTACCGATT
TGGGTGGCGAACTTTGTATTAATGCATTATGGTACGGGCGCGGTAATGGCGGTGCCGGCGCACGACCAACGCGACTTCGA
ATTTGCCACCAAATACGATTTGCCGATTAACCAGGTTATTGCGCCGGTGAACGGTGAAGACATCGATTTAAGCAAAGCGG
CGTTTACCGAACACGGTAAGCTGGTTAATTCGGCGGAATTCGACGGTTTGGATTTCGATGCGGCATTTAACGGCATTGCG
GACAAATTAGAACGAATGGGTGCAGGTAAACGTCAAGTGAATTATCGTTTACGCGACTGGGGCGTGTCCCGTCAACGTTA
CTGGGGGGCGCCGATTCCTATGCTGACGCTGGAAAACGGCGATGTGGTGCCGGCTCCGTTACAGGATTTGCCAATCGTTC
TGCCGGAAGATGTGGTAATGGACGGCGTGAAAAGTCCGATTAAAGCGGATCCGGACTGGGCGAAAACCACCTATAACGGT
CGGCCGGCGTTAAAAGAAACCGATACTTTCGATACCTTTATGGAATCTTCCTGGTATTATGCGCGTTATACTTGCCCGCA
ATATCACGAAGGTATGCTGGACAGCGAAGAAGCCAATTACTGGTTGCCGGTGGATCAATATATCGGCGGTATCGAACACG
CCACCATGCATTTGCTTTACTTCCGTTTCTTCCACAAACTGCTGCGGGACGCAGGCTTGGTTTCGACGGATGAACCGACT
AAAAAACTGCTTTGCCAAGGAATGGTGTTAGCGGACGCCTTCTATTACACCAGCCCGACTAACGAGCGTATTTGGGTGTC
ACCGACTAAAGTGACGCTGGAACGCGACGAAAAAGGCCGTATCGTTAAAGCGTTAGATGATGAAGGGCGCGAACTGGTAC
ACGCCGGTATGACCAAAATGTCGAAATCCAAAAACAACGGTATCGACCCGCAGGAAATGGTGGAAAAATACGGCGCCGAT
ACGGTACGTTTATTTATGATGTTCGCCTCTCCTGCAGAAATGACTCTTGAATGGCAGGAGTCCGGTGTGGAAGGTGCCAA
ACGTTTCTTAGGCCGTTTATGGAATTTAGTGTTCGAATATAATAAAAATCCGGCAAAAACTGCGCTAAATCCGACCGCAC
TTTCCGGCGTACAAAAAGCCTTGCGCCGCGGTGTCCATAAAACCATTGCGAAAGTGTCCGACGATATCGGTCGCCGCCAG
ACCTTTAATACGGCGATTGCCGCAATCATGGAATTAATGAATAAATTAACCCGTGCGTCATTAGCCGGCGAACAGGATCG
TGCAATTATGGGCGAAGCCTTAAGTGCGGTGGTGCGCATGCTTTACCCTATTACCCCGCACGTCTGTTTCCAATTATGGA
AAGAGCTGGGTAACGAAGATGTCATCGACTTTGCGCCGTGGGTTCAGGCGGACGAAGCGGCAATGGTGGAAGAGGAAAAG
CTGGTCGTGGTGCAGGTGAACGGCAAAGTCCGCGGTAAAATTACCGTGCCGGCGGATATGGCGGAAGACGACATTAAACA
AGCCGCCCTTGCGGACGAAAACGTGCAAAAATTCCTGAGCGGATTAAATATCGTAAAAACCATCTATGTGCCGGGTAAAT
TGTTCAGCTTTGTGGCGAAATAA

Protein sequence :
MQEQYRPDLIEAEVQKYWQENKTFKAIKDTNKEKYYCLSMLPYPSGRLHMGHVRNYTIGDVVSRYQRMIGKNVLQPMGWD
AFGLPAEGAAVKNNTAPAKWTYENIEYMKNQLKVLGFSYDWEREVTTCRPEYYKWEQWFFTELYKKGLVYKKTSVVNWCP
NDETVLANEQVHEGCCWRCDTPVEQREIPQWFIKITDYAEQLLGGLDTLPEWPEMVKTMQRNWIGRSEGVEITFKIENSD
ETVAVYTTRPDTFYGVSYMAVAAGHPLAERAAQNNPDLAKFIQECKNTKVAEAELATMEKKGMATGLNAVHPITGKPVPI
WVANFVLMHYGTGAVMAVPAHDQRDFEFATKYDLPINQVIAPVNGEDIDLSKAAFTEHGKLVNSAEFDGLDFDAAFNGIA
DKLERMGAGKRQVNYRLRDWGVSRQRYWGAPIPMLTLENGDVVPAPLQDLPIVLPEDVVMDGVKSPIKADPDWAKTTYNG
RPALKETDTFDTFMESSWYYARYTCPQYHEGMLDSEEANYWLPVDQYIGGIEHATMHLLYFRFFHKLLRDAGLVSTDEPT
KKLLCQGMVLADAFYYTSPTNERIWVSPTKVTLERDEKGRIVKALDDEGRELVHAGMTKMSKSKNNGIDPQEMVEKYGAD
TVRLFMMFASPAEMTLEWQESGVEGAKRFLGRLWNLVFEYNKNPAKTALNPTALSGVQKALRRGVHKTIAKVSDDIGRRQ
TFNTAIAAIMELMNKLTRASLAGEQDRAIMGEALSAVVRMLYPITPHVCFQLWKELGNEDVIDFAPWVQADEAAMVEEEK
LVVVQVNGKVRGKITVPADMAEDDIKQAALADENVQKFLSGLNIVKTIYVPGKLFSFVAK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 3e-157 41