Gene Information

Name : hemC (Asuc_0356)
Accession : YP_001343669.1
Strain : Actinobacillus succinogenes 130Z
Genome accession: NC_009655
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 403931 - 404860 bp
Length : 930 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGCAACAGGAAATATTAAAAATAGCCACCCGCCAAAGCCCGTTGGCATTATGGCAGGCGAATTTTGTGAAAGATCGTTT
AACTGAAATTTATCCCGATTTAACCGTTGAATTGGTGCCGATGGTTACGAAAGGCGATGTGATTTTAGATACGCCGTTGG
CTAAAATCGGCGGAAAAGGATTATTCGTCAAAGAATTGGAAAATGCTTTATTGAACGGCGACGCGGATATTGCCGTGCAT
TCGATGAAAGATGTACCGATGGAATTTCCCGCCGGTTTGGGGTTAAGCGTTATCTGTAAACGAGAAGATCCGCGCGATGC
TTTCGTATCCAACCGATATCGTACTTTGGATGACCTGCCGCCCGGCGCTATTGTGGGGACTTCCAGTTTACGTCGCCAGT
GTCAGTTAAAAAAACGGCGTCCGGATTTAAACATTCGGTCTTTGCGCGGCAATGTAGGTACAAGATTAAGCAAACTGGAT
CAAGGCGATTACGATGCCATTATTTTAGCGTCCGCCGGCTTGATTCGTTTAGCGCTGCCGGAGCGGATTGCGTCCTTTAT
CGAAACGGAAATTTCACTGCCGGCAGCGGGCCAAGGTGCCGTGGGTATAGAATGCCGTATCAACGATCAACGCGTACAAA
AATTGCTGGCACCGCTGGCGGATACGGAAACCACCGCCTGCGTACTGGCGGAACGGGCAATGAATAATCGTCTGCAAGGC
GGTTGTCAGGTGCCGATTGGCGGTTATGCCGTGTTAAACGGAAACGAACTGCATTTGCGTGCCTTAGTCGGTGCGTTGGA
CGGTTCAAAAATCATTCGTGCCGAAGGCAAAAGTGCGGTCGAAAATGCGGAAGTTTTGGGCATACAAATCGCAGAAAGTC
TGCTCGCTCAAGGCGCGGATAAAATATTGGCGGAAGTGTATAACGGTTAA

Protein sequence :
MQQEILKIATRQSPLALWQANFVKDRLTEIYPDLTVELVPMVTKGDVILDTPLAKIGGKGLFVKELENALLNGDADIAVH
SMKDVPMEFPAGLGLSVICKREDPRDAFVSNRYRTLDDLPPGAIVGTSSLRRQCQLKKRRPDLNIRSLRGNVGTRLSKLD
QGDYDAIILASAGLIRLALPERIASFIETEISLPAAGQGAVGIECRINDQRVQKLLAPLADTETTACVLAERAMNNRLQG
GCQVPIGGYAVLNGNELHLRALVGALDGSKIIRAEGKSAVENAEVLGIQIAESLLAQGADKILAEVYNG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 5e-88 65
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 5e-88 65