Gene Information

Name : Asuc_1726 (Asuc_1726)
Accession : YP_001345013.1
Strain : Actinobacillus succinogenes 130Z
Genome accession: NC_009655
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : 2.7.7.38
Position : 1895516 - 1896295 bp
Length : 780 bp
Strand : -
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence :
ATGACGACATTTACGGTAATTATTCCCGCGCGTTTTGCGTCAAGCCGCTTGCCGGGTAAACCGCTGGCGGATATCGCCGG
TAAACCCATGATCCGACACGTGTGGGAAAAAGCCCGTCGGTCGGGGGCAAGCCGTGTGGTCGTGGCGACGGATAACGAGC
AGGTCAAAAATGCGGTATTACAATTCGGCGGCGAAGTGTGTATGACGTCGGAAAAACACAATTCCGGCACGGAGCGTCTG
GCGGAAGTGGTAGAAAAATTAGATATCGCAGACGATGAAATTATCGTGAATATCCAAGGTGACGAGCCCTTGATTCCGCC
TGTCATTGTACAACAGGTGGCGGCGAACCTGGCAAAGTATCGGGTGAATATGGCAAGTTTGGCGGTGAAAATAGAGGATG
TCCAAGAACTTTTCAATCCTAATGCCGTCAAAGTGCTGACGGATCAGGCGGGATACGTTCTGTATTTTTCGCGGGCGGCG
ATTCCGTGGAACCGTGACGAATTTGCGGATATTGCGGCAAATACGAAAAATCTTGATGACTTACGGTTGGGTGATCATTA
TTTACGCCATATCGGCATTTATGCCTATCGTGCGGGATTTATCAAACGATATGTGCAATGGCAGCCGACGGCATTGGAAA
AAATCGAAAGTCTGGAGCAGCTGCGTGTGTTGTGGTATGGTGAACGCATTCATGTCGAACTTGCCGAAGAAGTACCGGCT
GTAGGCGTGGATACACCGGAAGATTTAGAAAAAGTGCGGTCGATTTTGACGGCGTTTTAA

Protein sequence :
MTTFTVIIPARFASSRLPGKPLADIAGKPMIRHVWEKARRSGASRVVVATDNEQVKNAVLQFGGEVCMTSEKHNSGTERL
AEVVEKLDIADDEIIVNIQGDEPLIPPVIVQQVAANLAKYRVNMASLAVKIEDVQELFNPNAVKVLTDQAGYVLYFSRAA
IPWNRDEFADIAANTKNLDDLRLGDHYLRHIGIYAYRAGFIKRYVQWQPTALEKIESLEQLRVLWYGERIHVELAEEVPA
VGVDTPEDLEKVRSILTAF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 4e-37 42
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 8e-37 42
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 3e-37 42