Gene Information

Name : Asuc_1706 (Asuc_1706)
Accession : YP_001344993.1
Strain : Actinobacillus succinogenes 130Z
Genome accession: NC_009655
Putative virulence/resistance : Unknown
Product : DNA topoisomerase III
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0550
EC number : 5.99.1.2
Position : 1873716 - 1875650 bp
Length : 1935 bp
Strand : +
Note : decatenates replicating daughter chromosomes

DNA sequence :
ATGCGATTATTTGTTGCTGAAAAACCCAGTCTGGCCCGCGCTATCGCCGATGTTCTGCCGAAACCGCACAGTCGCGGCGA
CGGTTTTATTCGCTGCGGCGAAAACGATTATGTAACGTGGTGCGTGGGACATTTACTGGAACAGGCGGAACCCGATGCCT
ACAACCCCAGCTACAAACAATGGCGGTTGGAACATTTACCTATCGTGCCGCAAAAATGGCAACTGATTCCCCGGAAAGAA
GTGGCTAAACAGCTGAAAATCGTAGAAAAGCTGATTCACCAGGCGGACGAACTGGTTAACGCCGGCGACCCTGATCGGGA
AGGTCAGTTATTGGTGGACGAAGTGTTCAGTTACGCCGATTTGCCGGCGGATAAAAAAGATAAAATTCAGCGTTGCTTAG
TGAGCGATCTCAACCCGAATGCGGTGGAAAAAGCCGTTAATAAGCTACAACCGAACCGCAATTTTATTCCTTTAGCGACC
TCCGCACTCGCCCGCGCCCGCGCCGACTGGCTGTACGGTATCAATATGACGCGCGCCTACACCATTCGCGGACGTCAAGC
CGGCTACAACGGCGTACTGTCCGTTGGACGCGTGCAAACGCCCGTGTTAGGACTCATTGTGCGACGCGATCTGGAAATCG
AAAATTTTCGACCGAAAGATTTTTTTGAAGTACTGGCGCAGATAAAAAGCGAACAAAATCCGACCGCACTTTCCTTCACC
GCCTTGTGGCAACCTTCCAAAGCCTGCGAAGATTATCAGGATGAAGACGGACGCGTGCTTTCCCGCGCTTTAGCGGAAAA
TGTGATTAAGCGCATTACTCGGCAACCGGCGGAAGTAACGGCATACGAAGATAAACGGGAAAAGCAAACCGCACCGCTGC
CCTATTCGCTTTCCGCTTTACAAATCGACGCGGCAAAACGTTTTGCTCTTTCCGCGCAGGATGTGTTGGACACCTGCCAG
AGTTTGTACGAAAAGCACAAGCTGATTACCTATCCGCGTTCCGATTGCCGTTATCTGCCGAACGAACATTTTGCCGATCG
TCATGCGGTGATGAACGCCATTTCCGTACATTGTACGGCATATCAAACGCTGCCGAGTGCGGTGAATTCCGAACAAAAAA
ACCGTTGCTGGAACGATAAAAAAGTGGAAGCACACCACGCTATTATTCCGACGGCAAAAAACCGTGCGGTAAGTTTAACC
GCGCGGGAACAAGACATTTACGGTTTGATTGCCCGACAATATCTCATGCAGTTCTGCCCGGACGCCGAATACCGCAAAAG
TAAAATCACCCTGAATATTGCAGGCGGCACCTTTATTGCGCAGGCGCGAAATTTACAGATAGCCGGCTGGAAAGAATTAA
TCGGCAAAGAAGATGACGACGAGCAACTTGAAGCGCCTTTGCCTGTGGTGAAAAAAGGGCAAATGCTGTTTTGCGAGAAA
GGCGAGATCGTCAGCAAGAAAACCCAACCGCCCAAACCGTTTACGGATGCGACATTGCTTTCCGCCATGACGGGTATCGC
CCGTTTCGTACAGGATAAAGAACTGAAAAAAATCCTGCGTGAAACCGACGGTTTAGGCACGGAAGCCACCCGGGCCGGTA
TTATCGAACTGTTATTCAAACGCGGATTTCTGTATAAAAAAGGGCGTAACATTCACAGTACCGAAGCAGGACGTATTCTG
ATTCAGGCATTGCCGGATCTGGCGACCCAGCCCGATATGACGGCACAATGGGAAGCACAGCTAAACGGCATCAGTCAAAA
AGAAACCAGTTATCAGTCTTTCATGTTTCAACTGACTCAAATGCTGCCGGAGTTGGTGCAATTCGTGAATTTTTCCGCCC
TGCGCCGACTGAGTGCCGTTGCCGACCGACCAAAGCCGACATTCAAACGCAAAGCAAGAAAAACAGCCGATAAAAGTGCG
GTCAAATCCGTTTAG

Protein sequence :
MRLFVAEKPSLARAIADVLPKPHSRGDGFIRCGENDYVTWCVGHLLEQAEPDAYNPSYKQWRLEHLPIVPQKWQLIPRKE
VAKQLKIVEKLIHQADELVNAGDPDREGQLLVDEVFSYADLPADKKDKIQRCLVSDLNPNAVEKAVNKLQPNRNFIPLAT
SALARARADWLYGINMTRAYTIRGRQAGYNGVLSVGRVQTPVLGLIVRRDLEIENFRPKDFFEVLAQIKSEQNPTALSFT
ALWQPSKACEDYQDEDGRVLSRALAENVIKRITRQPAEVTAYEDKREKQTAPLPYSLSALQIDAAKRFALSAQDVLDTCQ
SLYEKHKLITYPRSDCRYLPNEHFADRHAVMNAISVHCTAYQTLPSAVNSEQKNRCWNDKKVEAHHAIIPTAKNRAVSLT
AREQDIYGLIARQYLMQFCPDAEYRKSKITLNIAGGTFIAQARNLQIAGWKELIGKEDDDEQLEAPLPVVKKGQMLFCEK
GEIVSKKTQPPKPFTDATLLSAMTGIARFVQDKELKKILRETDGLGTEATRAGIIELLFKRGFLYKKGRNIHSTEAGRIL
IQALPDLATQPDMTAQWEAQLNGISQKETSYQSFMFQLTQMLPELVQFVNFSALRRLSAVADRPKPTFKRKARKTADKSA
VKSV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
topB AAN62317.1 putative DNA topoisomerase III Not tested PAGI-3(SG) Protein 2e-107 42
pph56 CAI36097.1 Topoisomerase IA Not tested PPHGI-1 Protein 1e-102 41
topB1 YP_005176228.1 DNA topoisomerase III Not tested ICEPmu1 Protein 7e-109 41