Gene Information

Name : Asuc_0111 (Asuc_0111)
Accession : YP_001343426.1
Strain : Actinobacillus succinogenes 130Z
Genome accession: NC_009655
Putative virulence/resistance : Virulence
Product : UDP-glucose/GDP-mannose dehydrogenase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0677
EC number : -
Position : 131284 - 132579 bp
Length : 1296 bp
Strand : -
Note : PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; KEGG: msu:MS1501 WecC protein

DNA sequence :
ATGAATCTAGACAGCTACAAAGTTGGCGTTGTCGGTCTTGGTTACGTGGGTTTGCCGTTAGCGGTAGAGTTCGGTAAACA
GCGGGAGACCATTGGCTTTGATATTAGCCCGAATAGGGTAAAAGAACTGGCAGAGGGTAAAGACCGGACTTTAGAAGTCT
CATCGGAAGCCCTCAAGTCAGCTACTCATCTTTCTTACACCTCTGATCTGGAACGGCTTAAGCGATGCAATTTTTTTATC
GTTACGGTTCCGACTCCCATTGATGATGTCAACCGCCCGGATTTAACACCGCTGCAGAAAGCCAGCGAATCCATCGGTAA
AGTGCTGAAAAAAGGCGATATCGTAGTGTATGAATCCACGGTATATCCCGGGGCTACGGAAGAAGTCTGTGTCCCTATTT
TGGAGCGGGTTTCCGGTTTGAAATTCAACCAGGATTTCTTTGCGGGTTATAGTCCGGAGCGGATTAATCCGGGCGATAAA
GTCAATACGCTTACTAAAATTAAAAAAATTACCAGCGGCAGTACGCCCGAAGTGGCGGATATTGTCGATCAAATGTACGG
CAGTATCATTACTGCGGGCACCCATAAAGCCGCCAGTATTAAAGTGGCGGAAGCGGCAAAAGTGATCGAAAACACTCAAC
GGGATTTGAATATTGCCTTAGTAAACGAATTATCCATCATTTTCGAACGGGTCGGTATCGATACGGTGGATGTGTTGGAA
GCGGCAGGCAGTAAATGGAACTTTTTACCGTTCCGCCCGGGTTTGGTGGGCGGACACTGTATCGGTGTCGATCCGTATTA
TTTAACTCACAAAGCGGAAGAGGTGGGGTATAACCCGCAGGTGATTCTTGCCGGTCGTCGCATTAATGACAATATGGCGC
ATTATGTGGCGCAAACCACCGTCAAATTAATGCTGAATCATAATATTGACGTCGCCAAAGCCAAAGTAGGTATTTTAGGG
GTGACGTTCAAGGAAAACTGTCCGGATATCCGTAACAGTAAAGTGGTTGATGTGATTCACGAGTTACGTAATTGGGGCGC
AGATGTGGTGGTCGCCGATCCTTGGGCCGATCCCGCCGAAGTAAAACACGAATACGGTTTGGATTTATCCGTGATTGATG
AAAATCACCCGGTGGATGCGCTGATTGTGGCGGTAGGTCATAAAGAGTTCCGGGAATTAAATCCGGAAATTCTGCGTACT
TATATGAATTCGTCTAATCCGGTATTGGTGGATGTGAAGAGTTTATTTGATCGAGATGCCTTATCACAGCAAGGTATCAG
TGTGTTCCGTTTATAA

Protein sequence :
MNLDSYKVGVVGLGYVGLPLAVEFGKQRETIGFDISPNRVKELAEGKDRTLEVSSEALKSATHLSYTSDLERLKRCNFFI
VTVPTPIDDVNRPDLTPLQKASESIGKVLKKGDIVVYESTVYPGATEEVCVPILERVSGLKFNQDFFAGYSPERINPGDK
VNTLTKIKKITSGSTPEVADIVDQMYGSIITAGTHKAASIKVAEAAKVIENTQRDLNIALVNELSIIFERVGIDTVDVLE
AAGSKWNFLPFRPGLVGGHCIGVDPYYLTHKAEEVGYNPQVILAGRRINDNMAHYVAQTTVKLMLNHNIDVAKAKVGILG
VTFKENCPDIRNSKVVDVIHELRNWGADVVVADPWADPAEVKHEYGLDLSVIDENHPVDALIVAVGHKEFRELNPEILRT
YMNSSNPVLVDVKSLFDRDALSQQGISVFRL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tviB NP_458740.1 Vi polysaccharide biosynthesis protein, UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 5e-120 62
tviB NP_807945.1 VI polysaccharide biosynthesis UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 5e-120 62
cap1L AAA64651.1 type 1 capsule synthesis gene Virulence SCCcap1 Protein 7e-111 58

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Asuc_0111 YP_001343426.1 UDP-glucose/GDP-mannose dehydrogenase VFG0431 Protein 2e-120 62