Gene Information

Name : guaA (Mmwyl1_4147)
Accession : YP_001342978.1
Strain : Marinomonas sp. MWYL1
Genome accession: NC_009654
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 4698446 - 4700023 bp
Length : 1578 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGTCGCAAGATATCCACGCTCATAAAATTCTTATTCTTGATTTCGGTTCTCAGTACACGCAACTGATTGCGCGTCGCGT
TCGTGAGATCGGTGTTTACTGTGAAGTTCGTGCTTTTGATATGGAAGATCAAGACGTTATCGACTTCGATCCAAAAGGCA
TCATCCTTGCTGGTGGCCCTGAATCCGTTCCAGAGCCAGGTTCTCCACGTGCACCAGAAGCAGTATTTACATTGGGTGTG
CCGGTATTTGGTATTTGTTACGGCATGCAAACCATGGCAGAGCAATTGGGCGGTAAAGTTCAAGGTTCTGAAATCCGTGA
GTTTGGTTACGCGCAAATTCGTAAGCACGAAGGTCCAGCTCTGTTTGACGACATTCAAGACCACATTGCTAACAACGGCG
TTGCTTTGTTAGATGTTTGGATGAGTCATGGCGATAAAGTTATCACCATGCCAGAAGACTTTACTTTAATGGCGTCAACG
GACAGCTGCCCAATTGCGGCTATGGCCAACGAAGCGAAGAAATTCTACGGTGTACAATTCCACCCAGAAGTAACTCATAC
GTTACAAGGTGGCCGTATCCTATCTCGTTTCATCGTCGATATTTGTGGTTGTGATACTTTGTGGACGCCTGCCAACATCG
CACAAGATGCGATTGAACGCATGCAAGAACAAGTAGGTGACAAAAAAGTTCTTTTAGCTCTTTCTGGTGGCGTGGATTCT
TCTGTTGTAGCAGCATTGCTTCATAAAGCGATTGGCGACCAATTGACTTGTGTATTTGTCGACAACGGCTTGCTTCGTCT
ACATGAAGGCGATCAAGTCATGAAAATGTTTGCCGACAACATGGGCGTAAAAGTGATTCGTGTTGATGCGGAAGACTTGT
TCCTTGGAAAACTAGCAAACGAAGCGGACCCAGAGAAAAAGCGTAAGATCATTGGTAACACCTTCATCGACGTATTCGAC
ACAGAAGCGACCAAACTGACGGATGTAGAGTTCCTTGCACAAGGTACTATTTACCCAGACGTGATTGAATCTGCTGCGTC
TAAAACAGGCAAAGCACACGTTATCAAATCTCACCACAACGTAGGTGGTCTGCCAGAGGACATGCAATTCAAACTGGTTG
AGCCTTTGCGTGAACTGTTCAAAGACGAAGTGCGTAAGCTAGGTCTTGAACTAGGCCTACCGTATGACATGGTTTACCGT
CATCCTTTCCCAGGACCAGGTCTAGGTGTTCGTATCCTTGGCGAAGTGAAGAAAGAATACGCCGACATTCTACGTCGTGC
TGATGCTATCTTCATCGAAGAGCTACGCAACGCTGGCTGGTACGAGAAAACAAGCCAAGCTTTCGCGGTATTCCTTCCAG
TTAAATCTGTTGGCGTAGTAGGCGACGGCCGCCGTTACGAATACGTGGTAGCACTTCGTGCCGTTGAAACCATCGACTTC
ATGACAGCTCGTTGGGCGCACCTACCGTACGAACTGCTAGAGAAAGTGTCTGGTCGTATCATCAACGAAATCGAACACAT
CTCCCGCGTGACTTACGACGTATCCTCTAAGCCACCTGCTACTATCGAGTGGGAATAA

Protein sequence :
MSQDIHAHKILILDFGSQYTQLIARRVREIGVYCEVRAFDMEDQDVIDFDPKGIILAGGPESVPEPGSPRAPEAVFTLGV
PVFGICYGMQTMAEQLGGKVQGSEIREFGYAQIRKHEGPALFDDIQDHIANNGVALLDVWMSHGDKVITMPEDFTLMAST
DSCPIAAMANEAKKFYGVQFHPEVTHTLQGGRILSRFIVDICGCDTLWTPANIAQDAIERMQEQVGDKKVLLALSGGVDS
SVVAALLHKAIGDQLTCVFVDNGLLRLHEGDQVMKMFADNMGVKVIRVDAEDLFLGKLANEADPEKKRKIIGNTFIDVFD
TEATKLTDVEFLAQGTIYPDVIESAASKTGKAHVIKSHHNVGGLPEDMQFKLVEPLRELFKDEVRKLGLELGLPYDMVYR
HPFPGPGLGVRILGEVKKEYADILRRADAIFIEELRNAGWYEKTSQAFAVFLPVKSVGVVGDGRRYEYVVALRAVETIDF
MTARWAHLPYELLEKVSGRIINEIEHISRVTYDVSSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 1e-128 53
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 2e-128 53
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 1e-128 53
guaA NP_938969.1 GMP synthase Not tested Not named Protein 6e-114 49