Gene Information

Name : lysS (Mmwyl1_1132)
Accession : YP_001339996.1
Strain : Marinomonas sp. MWYL1
Genome accession: NC_009654
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : -
Position : 1267475 - 1268977 bp
Length : 1503 bp
Strand : +
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
ATGGCTAACGAAAATAACACAGAATCCACAGCACAATCTGACGACAATCGATTAGTAGCGGAACGTCGCGGCAAATTGGC
TGCTATTCGTGCAGAGCGAAATGCTTACCCAAATACATTTCGTCCAAACGCTTATGCAGCAGACCTTCAAGCAGAATTCG
GTGAACTAGAAAAAACTGAGTTAGAAGAGAAAGATCATAAAGTTAGCATCGCTGGTCGTATTATTCGTAACCGTGGCGCT
TTTATGTTGCTACAAGACATGACAGGTCAAATCCAAGCTTATGTGAATCGTAAAGTCTTGAGCCCTGAGCTATTGGCAGA
TCAAAAAACATGGGATCTGGGGGATATCATCGGTATTTCTGGTCCTGTGCACAAGTCAGGTAAAGGGGATTTGTACATTG
ATATGCACGAAGCGCAATTACTAACCAAGTCTCTACGTCCGTTGCCAGATAAGCATCACGGTTTGTCTGATATGGAAATG
CGCTACCGTCAGCGTTACGTTGATTTGATCGTAAATGAAGAGTCTCGCGAGACTTTCCAAATGCGTTCAAAAATCATCTC
TACGATTCGTCGCTTCCTAGAAGATCGTCGTTTCATGGAAGTTGAAACGCCAATGCTACAAACTATTCCAGGTGGTGCAT
CAGCTCGTCCATTTATTACGCATCACAATGCGATGGATATGAGCATGTACTTGCGTATTGCGCCAGAGCTTTATTTGAAG
CGTTTGGTTGTAGGTGGTTTTGAGCGTGTATTCGAGATTAATCGTAACTTCCGTAACGAAGGGACATCCACACGTCATAA
TCCAGAATTCACCATGATCGAATTCTACCAAGCGTATGCAGACTACAAAGATTTAATGGATCTGACTGAAGATATGTTGC
GTACAGTCGCTGAAAAAGTGTTGGGCACAACGACAGTCACTTACCAAGGTTCTGAATATGACTTTGGCGCGCCGTTTGTT
CGCATGAGTATGCTGGATTCGATTTTGCACTACAACCCAGAATTAACTGCGGCAGATCTAGAAACGCTGGAAGGCGCGAC
AGCTGTTGCGAAGAAACTAAAAATCGACGTGAAACCAATTTGGGGCTTGGGTAAACTTTGGACAGAAATCTTCGAAGAAA
CCGCAGAGCATAAATTGGATCAACCGACTTTCATTACGGAATACCCAGCAGAAGTGTCTCCACTGGCGCGTCGTAATGAT
GATAATGATTTCATTACCGACCGTTTTGAATTCTTCGTTGGTGGTCGTGAAATTGCTAACGGTTTCTCGGAGCTTAACGA
TCCAGAAGACCAAGCAGAGCGTTTCATGCGTCAGGTTGCAGAAAAAGACGCGGGTGATGATGAAGCCATGCATTACGATG
CAGACTACATCAATGCTCTAGAGTACGGCCTACCACCAACCGCTGGTGAAGGTATTGGTATCGACCGTTTGGTGATGTTG
TTCACCGATGCGCCTTCGATCCGCGACGTATTATTGTTCCCACATATGAAGCCTCAGGACTGA

Protein sequence :
MANENNTESTAQSDDNRLVAERRGKLAAIRAERNAYPNTFRPNAYAADLQAEFGELEKTELEEKDHKVSIAGRIIRNRGA
FMLLQDMTGQIQAYVNRKVLSPELLADQKTWDLGDIIGISGPVHKSGKGDLYIDMHEAQLLTKSLRPLPDKHHGLSDMEM
RYRQRYVDLIVNEESRETFQMRSKIISTIRRFLEDRRFMEVETPMLQTIPGGASARPFITHHNAMDMSMYLRIAPELYLK
RLVVGGFERVFEINRNFRNEGTSTRHNPEFTMIEFYQAYADYKDLMDLTEDMLRTVAEKVLGTTTVTYQGSEYDFGAPFV
RMSMLDSILHYNPELTAADLETLEGATAVAKKLKIDVKPIWGLGKLWTEIFEETAEHKLDQPTFITEYPAEVSPLARRND
DNDFITDRFEFFVGGREIANGFSELNDPEDQAERFMRQVAEKDAGDDEAMHYDADYINALEYGLPPTAGEGIGIDRLVML
FTDAPSIRDVLLFPHMKPQD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 8e-140 59
lysS YP_005163386.1 lysyl-tRNA synthetase Not tested Not named Protein 6e-83 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_001339996.1 lysyl-tRNA synthetase VFG1668 Protein 4e-140 59