Gene Information

Name : tetD (KPN_pKPN5p08256)
Accession : YP_001338866.1
Strain :
Genome accession: NC_009651
Putative virulence/resistance : Resistance
Product : tetracycline resistance protein, efflux, class D
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 85914 - 87098 bp
Length : 1185 bp
Strand : +
Note : -

DNA sequence : 
ATGAATAAACCCGCTGTCATCGCGCTGGTGATTACACTGCTGGACGCGATGGGAATTGGTCTGATCATGCCGGTATTACC
GTCACTGCTGCGGGAATATCTCCCGGAAGCGGATGTGGCAAACCATTACGGCATTCTGCTGGCGCTGTATGCGGTGATGC
AGGTCTGTTTTGCTCCGCTGCTGGGCAGATGGTCAGATAAGCTGGGGCGCAGACCGGTGCTGCTGTTATCCCTGGCGGGT
GCCGCGTTTGATTACACACTGCTGGCACTGTCCAATGTGCTGTGGATGTTGTATCTCGGGCGGATTATCTCCGGGATCAC
TGGTGCCACCGGCGCGGTTGCGGCTTCGGTAGTGGCGGACAGCACGGCGGTCAGCGAGCGTACCGCCTGGTTCGGCCGTC
TCGGTGCGGCCTTTGGTGCCGGGCTGATTGCCGGGCCGGCTATCGGCGGACTGGCGGGGGATATCTCACCGCATCTGCCG
TTTGTCATTGCGGCAATACTGAATGCCTGCACCTTTCTGATGGTCTTTTTTATCTTTAAACCGGCGGTACAGACAGAAGA
AAAACCGGCGGAGCAGAAACAAGAAAGCGCAGGTATCAGCTTTATCACACTGCTTAAACCTCTGGCGCTGTTGCTGTTTG
TCTTTTTTACCGCGCAGCTTATCGGGCAGATCCCGGCCACTGTCTGGGTATTGTTTACGGAGAGCCGCTTTGCCTGGGAC
AGCGCGGCGGTCGGTTTTTCACTGGCGGGACTCGGGGCGATGCATGCACTGTTTCAGGCGGTGGTTGCCGGGGCGCTGGC
AAAACGGCTGAGTGAGAAAACCATTATTTTCGCCGGATTTATTGCCGATGCCACCGCGTTTTTACTGATGTCTGCTATCA
CTTCCGGATGGATGGTGTATCCGGTCCTGATCCTGCTGGCAGGCGGCGGAATTGCACTGCCTGCATTGCAGGGCATTATC
TCTGCCGGGGCATCGGCGGCAAATCAGGGAAAACTACAGGGTGTGCTGGTCAGCCTGACCAATCTGACCGGCGTGGCGGG
CCCGCTGCTGTTTGCTTTTATTTTCAGTCAGACACAGCAGAGTGCGGACGGTACGGTGTGGCTGATTGGCACGGCACTGT
ACGGTCTGCTGCTGGCAATCTGTCTGCTGATCAGAAAACCGGCACCGGTGGCGGCCACCTGCTGA

Protein sequence : 
MNKPAVIALVITLLDAMGIGLIMPVLPSLLREYLPEADVANHYGILLALYAVMQVCFAPLLGRWSDKLGRRPVLLLSLAG
AAFDYTLLALSNVLWMLYLGRIISGITGATGAVAASVVADSTAVSERTAWFGRLGAAFGAGLIAGPAIGGLAGDISPHLP
FVIAAILNACTFLMVFFIFKPAVQTEEKPAEQKQESAGISFITLLKPLALLLFVFFTAQLIGQIPATVWVLFTESRFAWD
SAAVGFSLAGLGAMHALFQAVVAGALAKRLSEKTIIFAGFIADATAFLLMSAITSGWMVYPVLILLAGGGIALPALQGII
SAGASAANQGKLQGVLVSLTNLTGVAGPLLFAFIFSQTQQSADGTVWLIGTALYGLLLAICLLIRKPAPVAATC

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tetB AEA34667.1 tetracycline resistance determinant Not tested Not named Protein 4e-69 63
tetA(B) AEZ06045.1 tetracycline efflux protein Not tested Tn6167 Protein 5e-69 63
tetA(B) AAL08445.1 tetracycline resistance protein TetA(B) Not tested SRL Protein 6e-69 63
BJAB07104_00277 YP_008207742.1 Permeases of the major facilitator superfamily Not tested AbaR25 Protein 9e-69 63
BJAB0868_00281 YP_008211607.1 Permeases of the major facilitator superfamily Not tested AbaR26 Protein 9e-69 63
tetA(B) AEQ20905.1 tetracycline resistance protein Not tested Tn6166 Protein 9e-69 63
tetA YP_005797160.1 tetracycline resistance protein, class G (TETA(G)) Not tested AbaR4e Protein 6e-67 63
ABZJ_00260 YP_005524216.1 Tetracycline resistance protein, class B (TETA(B) ) (Metal-tetracycline/H(+) antiporter) Not tested AbaR22 Protein 8e-69 63
tetA(B) AFH57202.1 tetracycline resistance protein Not tested AbaR4a Protein 7e-69 63
tetA CAJ77034.1 Tetracycline resistance protein Not tested AbaR1 Protein 2e-58 54
tet(H) YP_005176248.1 tetracycline efflux protein, class H Not tested ICEPmu1 Protein 7e-53 54
tet(G) AAK02051.1 tetracycline resistance protein Not tested SGI1 Protein 4e-55 53
tetA(G) ABZ01843.1 TetA(G) Not tested SGI2 Protein 4e-55 53
tetA(G) AGK06974.1 TetA(G) Not tested SGI1 Protein 4e-55 53
tetA(G) AGK07104.1 TetA(G) Not tested SGI1 Protein 4e-55 53
tetA YP_006098396.1 tetracycline resistance protein Not tested Tn2411 Protein 2e-48 48
tetA(A) ACK44537.1 TetA(A) Not tested SGI1 Protein 1e-48 48
tetA(A) AGK07027.1 TetA(A) Not tested SGI1 Protein 1e-48 48
tetA(A) AGK07085.1 TetA(A) Not tested SGI1 Protein 1e-48 48
tetA CAJ77066.1 Tetracycline resistance protein Not tested AbaR1 Protein 8e-49 48
tetA(A) ACN81011.1 TetA(A) Not tested AbaR5 Protein 1e-48 48

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
tetD YP_001338866.1 tetracycline resistance protein, efflux, class D L06798.gene.p01 Protein 3e-124 100
tetD YP_001338866.1 tetracycline resistance protein, efflux, class D V00611.gene.p01 Protein 4e-68 63
tetD YP_001338866.1 tetracycline resistance protein, efflux, class D AB084246.gene.p01 Protein 3e-69 63
tetD YP_001338866.1 tetracycline resistance protein, efflux, class D NC_010558.1.6275971. Protein 4e-69 63
tetD YP_001338866.1 tetracycline resistance protein, efflux, class D AJ250203.gene.p01 Protein 2e-59 59
tetD YP_001338866.1 tetracycline resistance protein, efflux, class D L06940.gene.p01 Protein 1e-63 57
tetD YP_001338866.1 tetracycline resistance protein, efflux, class D Y19116.gene.p01 Protein 5e-62 56
tetD YP_001338866.1 tetracycline resistance protein, efflux, class D AF133139.gene.p01 Protein 7e-57 54
tetD YP_001338866.1 tetracycline resistance protein, efflux, class D NC_010410.6002612.p0 Protein 1e-58 54
tetD YP_001338866.1 tetracycline resistance protein, efflux, class D AF133140.gene.p01 Protein 1e-58 54
tetD YP_001338866.1 tetracycline resistance protein, efflux, class D Y15510.gene.p01 Protein 1e-53 54
tetD YP_001338866.1 tetracycline resistance protein, efflux, class D CP004022.1.gene2534. Protein 3e-53 53
tetD YP_001338866.1 tetracycline resistance protein, efflux, class D AF038993.gene.p01 Protein 3e-53 53
tetD YP_001338866.1 tetracycline resistance protein, efflux, class D AF070999.gene.p01 Protein 5e-50 50
tetD YP_001338866.1 tetracycline resistance protein, efflux, class D NC_011586.7045189.p0 Protein 1e-43 48
tetD YP_001338866.1 tetracycline resistance protein, efflux, class D AF534183.gene.p01 Protein 6e-49 48
tetD YP_001338866.1 tetracycline resistance protein, efflux, class D NC_010410.6002597.p0 Protein 5e-49 48
tetD YP_001338866.1 tetracycline resistance protein, efflux, class D CP001485.1.gene2821. Protein 5e-49 48
tetD YP_001338866.1 tetracycline resistance protein, efflux, class D Y19114.gene.p01 Protein 1e-47 47
tetD YP_001338866.1 tetracycline resistance protein, efflux, class D X75761.gene.p01 Protein 2e-47 47
tetD YP_001338866.1 tetracycline resistance protein, efflux, class D AF121000.gene.p01 Protein 1e-42 45
tetD YP_001338866.1 tetracycline resistance protein, efflux, class D AY264780.2.gene3.p01 Protein 2e-41 44
tetD YP_001338866.1 tetracycline resistance protein, efflux, class D AY743590.gene.p01 Protein 8e-39 43
tetD YP_001338866.1 tetracycline resistance protein, efflux, class D AJ420072.gene.p01 Protein 1e-38 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
tetD YP_001338866.1 tetracycline resistance protein, efflux, class D VFG1036 Protein 4e-69 63