Gene Information

Name : cmlA1 (KPN_pKPN5p08202)
Accession : YP_001338812.1
Strain :
Genome accession: NC_009651
Putative virulence/resistance : Resistance
Product : chloramphenicol resistance protein
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG2814
EC number : -
Position : 35447 - 36754 bp
Length : 1308 bp
Strand : -
Note : -

DNA sequence :
TTGCTCTACGGGAGCGCCGCCAAATCCTTTGTTCAAGGAGATGGTTTCGTGCGCTCAAAAAACTTTAGTTGGCGGTACTC
CCTTGCCGCCACGGTGTTGTTGTTATCACCGTTCGATTTATTGGCATCACTCGGCATGGACATGTACTTGCCAGCAGTGC
CGTTTATGCCAAACGCGCTTGGTACGACAGCGAGCACAATTCAGCTTACGCTGACAACGTACTTGGTCATGATTGGTGCC
GGTCAGCTCTTGTTTGGACCGCTATCGGACCGACTGGGGCGCCGCCCCGTTCTACTGGGAGGTGGCCTCGCCTACGTTGT
GGCGTCAATGGGCCTCGCTCTTACGTCATCGGCTGAAGTCTTTCTGGGGCTTCGGATTCTTCAGGCTTGTGGTGCCTCGG
CGTGCCTTGTTTCCACATTTGCAACAGTACGTGACATTTACGCAGGTCGCGAGGAAAGTAATGTCATTTACGGCATACTC
GGATCCATGCTGGCCATGGTCCCGGCGGTAGGCCCATTGCTCGGAGCGCTCGTCGACATGTGGCTTGGGTGGCGGGCTAT
CTTTGCGTTTCTAGGTTTGGGCATGATCGCTGCATCTGCAGCAGCGTGGCGATTCTGGCCTGAAACCCGGGTGCAACGAG
TTGCGGGCTTGCAATGGTCGCAGCTGCTACTCCCCGTTAAGTGCCTGAACTTCTGGTTGTACACGTTGTGTTACGCCGCT
GGAATGGGTAGCTTCTTCGTCTTTTTCTCCATTGCGCCCGGACTAATGATGGGCAGGCAAGGTGTGTCTCAGCTTGGCTT
CAGCCTGCTGTTCGCCACAGTGGCAATTGCCATGGTGTTTACGGCTCGTTTTATGGGGCGTGTGATACCCAAGTGGGGCA
GCCCAAGTGTCTTGCGAATGGGAATGGGATGCCTGATAGCTGGAGCAGTATTGCTTGCCATCACCGAAATATGGGCTTCG
CAGTCCGTGTTAGGCTTTATTGCTCCAATGTGGCTAGTGGGTATTGGTGTCGCCACAGCGGTATCTGTGTCGCCCAATGG
CGCTCTTCGAGGATTCGACCATGTTGCTGGAACGGTCACGGCAGTCTACTTCTGCTTGGGCGGTGTACTGCTAGGAAGCA
TCGGAACGTTGATCATTTCGCTGTTGCCGCGCAACACGGCTTGGCCGGTTGTCGTGTACTGTTTGACCCTTGCAACAGTC
GTGCTCGGTCTGTCTTGTGTTTCCCGAGTGAAGGGCTCTCGCGGCCAGGGGGAGCATGATGTGGTCGCGCTACAAAGTGC
GGAAAGTACATCAAATCCCAATCGTTGA

Protein sequence :
MLYGSAAKSFVQGDGFVRSKNFSWRYSLAATVLLLSPFDLLASLGMDMYLPAVPFMPNALGTTASTIQLTLTTYLVMIGA
GQLLFGPLSDRLGRRPVLLGGGLAYVVASMGLALTSSAEVFLGLRILQACGASACLVSTFATVRDIYAGREESNVIYGIL
GSMLAMVPAVGPLLGALVDMWLGWRAIFAFLGLGMIAASAAAWRFWPETRVQRVAGLQWSQLLLPVKCLNFWLYTLCYAA
GMGSFFVFFSIAPGLMMGRQGVSQLGFSLLFATVAIAMVFTARFMGRVIPKWGSPSVLRMGMGCLIAGAVLLAITEIWAS
QSVLGFIAPMWLVGIGVATAVSVSPNGALRGFDHVAGTVTAVYFCLGGVLLGSIGTLIISLLPRNTAWPVVVYCLTLATV
VLGLSCVSRVKGSRGQGEHDVVALQSAESTSNPNR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cml(A)5 ACY75522.1 CmLA(5) Not tested Tn6060 Protein 7e-160 99
cmlA5 CAJ77046.1 Chloramphenicol resistance protein Not tested AbaR1 Protein 1e-167 99
floR YP_005176183.1 florfenicol / chloramphenicol efflux protein Not tested ICEPmu1 Protein 4e-62 51
cmlA9 ABZ01840.1 CmlA9 chloramphenicol efflux protein Not tested SGI2 Protein 3e-62 50
cmlA CAJ77032.1 chloramphenicol and florfenicol resistance protein Not tested AbaR1 Protein 3e-62 50
flo AAK02049.1 chloramphenicol and florfenicol resistance protein Not tested SGI1 Protein 4e-63 50
floRc AGK06972.1 chloramphenicol and florfenicol resistance protein Not tested SGI1 Protein 4e-63 50
floRc AGK07102.1 chloramphenicol and florfenicol resistance protein Not tested SGI1 Protein 4e-63 50

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
cmlA1 YP_001338812.1 chloramphenicol resistance protein AF294653.1.gene4.p01 Protein 4e-159 99
cmlA1 YP_001338812.1 chloramphenicol resistance protein DQ984668.gene.p01 Protein 4e-160 99
cmlA1 YP_001338812.1 chloramphenicol resistance protein DQ522237.1.gene4.p01 Protein 4e-160 99
cmlA1 YP_001338812.1 chloramphenicol resistance protein NC_010410.6003586.p0 Protein 4e-160 99
cmlA1 YP_001338812.1 chloramphenicol resistance protein AF156486.gene.p01 Protein 1e-156 98