Gene Information

Name : silR (KPN_pKPN3p05950)
Accession : YP_001338559.1
Strain :
Genome accession: NC_009649
Putative virulence/resistance : Virulence
Product : DNA-binding transcriptional activator CusR
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 90649 - 91332 bp
Length : 684 bp
Strand : +
Note : response regulator in two-component regulatory system with CusS; regulates the copper efflux system

DNA sequence : 
ATGATGAAAATATTAATCGTTGAAGACGAAATTAAAACAGGTGAATATCTCAGCAAGGGGCTGACAGAGGCGGGGTTCGT
CGTGGATCACGCTGATAATGGTCTGACCGGATATCATCTTGCCATGACAGCCGAGTATGATTTAGTCATCCTGGATATCA
TGCTGCCTGATGTAAACGGCTGGGATATCATCCGTATGCTGCGCAGTGCCGGAAAGGGGATGCCGGTATTACTGCTGACG
GCCCTTGGCACGATTGAACACAGGGTCAAAGGACTTGAGCTGGGTGCGGACGATTATCTGGTGAAGCCCTTTGCGTTTGC
TGAACTGCTCGCCCGGGTAAGAACCCTCCTCAGGCGGGGAAACACGATGATCACGGAAAGCCAGCTTAAAGTGGCTGACC
TCTCGGTTGATCTCGTATCCAGAAAAGTCAGCCGCGCCGGGAACCGCATTGTGCTCACCAGTAAAGAGTTCAGCTTGCTG
GAATTCTTCATTCGCCATCAGGGAGAAGTTCTTCCCCGCTCCCTGATTGCCTCTCAGGTCTGGGACATGAATTTTGACAG
CGACACTAACGCGATTGATGTCGCAGTAAAGCGACTCCGCGCTAAAATAGACAACGATTACGGGACAAAACTGATCCAGA
CAGTGCGGGGCGTGGGCTACATGCTGGAGATCCCGGATGCATAG

Protein sequence : 
MMKILIVEDEIKTGEYLSKGLTEAGFVVDHADNGLTGYHLAMTAEYDLVILDIMLPDVNGWDIIRMLRSAGKGMPVLLLT
ALGTIEHRVKGLELGADDYLVKPFAFAELLARVRTLLRRGNTMITESQLKVADLSVDLVSRKVSRAGNRIVLTSKEFSLL
EFFIRHQGEVLPRSLIASQVWDMNFDSDTNAIDVAVKRLRAKIDNDYGTKLIQTVRGVGYMLEIPDA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
copR NP_460069.2 transcriptional regulatory protein YedW Not tested SPI-5 Protein 2e-55 55
copR AAC33719.1 regulatory protein CopR Not tested SPI-5 Protein 4e-55 53

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
silR YP_001338559.1 DNA-binding transcriptional activator CusR BAC0347 Protein 4e-96 96
silR YP_001338559.1 DNA-binding transcriptional activator CusR BAC0111 Protein 1e-94 87
silR YP_001338559.1 DNA-binding transcriptional activator CusR BAC0083 Protein 9e-71 62
silR YP_001338559.1 DNA-binding transcriptional activator CusR BAC0638 Protein 5e-65 62
silR YP_001338559.1 DNA-binding transcriptional activator CusR BAC0197 Protein 1e-65 60
silR YP_001338559.1 DNA-binding transcriptional activator CusR BAC0308 Protein 2e-62 59
silR YP_001338559.1 DNA-binding transcriptional activator CusR BAC0125 Protein 6e-64 57
silR YP_001338559.1 DNA-binding transcriptional activator CusR HE999704.1.gene1202. Protein 4e-37 42
silR YP_001338559.1 DNA-binding transcriptional activator CusR AE000516.2.gene3505. Protein 3e-27 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
silR YP_001338559.1 DNA-binding transcriptional activator CusR VFG0596 Protein 7e-56 55
silR YP_001338559.1 DNA-binding transcriptional activator CusR VFG1390 Protein 1e-42 43
silR YP_001338559.1 DNA-binding transcriptional activator CusR VFG1389 Protein 3e-34 41