Gene Information

Name : kdsB (KPN_00945)
Accession : YP_001334611.1
Strain : Klebsiella pneumoniae subsp. pneumoniae MGH 78578
Genome accession: NC_009648
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : -
Position : 1065295 - 1066041 bp
Length : 747 bp
Strand : +
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence : 
ATGAGTTTCGTGGTCATTATTCCTGCGCGTTTCGCCTCCACGCGCCTGCCGGGAAAACCACTGCAGGACATTAATGGTAA
GCCGATGATTGTCCATGTGCTGGAGCGCGCTCGCGAATCCGGCGCGGATCGCATTATTGTCGCCACCGATCACGAAGATG
TCGCCCGGGCGGTTGAAGCCGCCGGCGGCGAGGTCTGTATGACCCGCGCCGACCATCAGTCCGGCACCGAACGGCTGGCG
GAAGTGGTGGAAAAGTGCGCGTTCAGCGATGACACCATTATCGTCAATATTCAGGGCGATGAGCCGATGATCCCCCCGGC
GATTGTCCGCCAGGTGGCGGAGAATCTGGCTGCCAGCAGCAGCGGAATGGCGACGCTGGCGGTACCGATCCATGATGCGG
AAGAGGCGTTTAACCCGAATGCGGTCAAAGTGGTGATGGATGCCAAGGGTTACGCGCTCTATTTCTCCCGCGCGACTATT
CCCTGGGATCGCGATCGCTTTGCCCAATCCCGCGAGACCATCGGTGACTCCCTGCTGCGTCACATCGGCATCTATGGCTA
TCGCGCCGGCTTTATCCGCCGCTATGTCAGCTGGGCGCCGAGCCCGCTGGAGCAGATTGAAATGCTCGAGCAGCTGCGAG
TGCTGTGGTATGGCGAGAAAATCCATGTCGCCGTGGCGGCGGAAGTGCCCGGCACCGGCGTGGATACCCCGGAAGATCTG
GAGCGCGTCCGCGCTGAGCTGCGTTAG

Protein sequence : 
MSFVVIIPARFASTRLPGKPLQDINGKPMIVHVLERARESGADRIIVATDHEDVARAVEAAGGEVCMTRADHQSGTERLA
EVVEKCAFSDDTIIVNIQGDEPMIPPAIVRQVAENLAASSSGMATLAVPIHDAEEAFNPNAVKVVMDAKGYALYFSRATI
PWDRDRFAQSRETIGDSLLRHIGIYGYRAGFIRRYVSWAPSPLEQIEMLEQLRVLWYGEKIHVAVAAEVPGTGVDTPEDL
ERVRAELR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 3e-34 46
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 3e-34 46
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 2e-34 46