Gene Information

Name : serS (KPN_00925)
Accession : YP_001334591.1
Strain : Klebsiella pneumoniae subsp. pneumoniae MGH 78578
Genome accession: NC_009648
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : -
Position : 1038711 - 1040003 bp
Length : 1293 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGCTCGATCCCAATCTGCTGCGTACCGAGCCAGACGCAGTCGCAGAAAAACTGGCACGCCGGGGCTTTAAGCTGGATGT
AGATAAACTTCGCGCGCTTGAAGAGCGTCGTAAAGTTCTGCAGGTGCAAACGGAAAACCTGCAGGCGGAGCGTAACTCCC
GATCGAAATCCATTGGCCAGGCGAAAGCGCGCGGGGAAGACATCGAGCCATTACGCCTGGAAGTTAACAAGCTTGGCGAA
CAACTGGATGCTGCAAAATCCGAGCTGGAAACGCTGCTGGCGGAAATTCGCGATATCGCGCTGGCGATCCCGAATATTCC
TCATGATGATGTGCCGGTTGGTCGCGATGAAAACGACAACGTTGAAGTTAGCCGCTGGGGTACGCCGCGTCAGTTCGATT
TTGAGGTGCGCGATCATGTGACGCTGGGTGAAATGCACGGGGGGCTGGATTTTGCCGCCGCCGTTAAGCTCACCGGCTCG
CGCTTCGTGGTGATGAAAGGGCAGCTGGCCCGTCTGCACCGCGCCCTGGCGCAGTTCATGCTGGATCTGCACACCGAACA
GCATGGCTACAGCGAAAACTATGTCCCGTACCTGGTAAACCAGGACACCCTGTATGGCACTGGCCAGCTGCCGAAATTCG
CCGGCGACCTGTTCCATACCCGTCCGCTGGAAGAAGAGGCTGACAGCAGCAACTACGCGCTGATCCCGACGGCGGAAGTG
CCGCTGACCAACCTGGTGCGCGATGAAATCATCGACGAAGACGATCTGCCGATCAAAATGACCGCCCATACGCCGTGCTT
CCGCTCTGAAGCCGGTTCCTATGGCCGCGACACCCGCGGTCTGATCCGTATGCACCAGTTCGATAAAGTTGAAATGGTGC
AGATCGTCCGCCCGGAAGACTCTATGGCCGCGCTGGAAGAGATGACCGGTCACGCCGAGAAAGTGCTGCAGCTGCTGGGC
CTGCCGTACCGTAAGGTCGCGCTGTGCACCGGCGATATGGGCTTCAGCGCCTGCAAAACCTATGACCTCGAAGTATGGGT
TCCGGCGCAAAACACTTATCGTGAGATCTCCTCCTGCTCCAACGTCTGGGATTTCCAGGCGCGTCGTATGCAGGCTCGCT
GCCGCAGCAAGTCCGATAAGAAGACCCGTCTCGTTCATACCCTGAATGGTTCTGGCCTGGCAGTAGGTCGTACCCTGGTG
GCGCTGATGGAAAACTATCAGCAGGCTGATGGCCGTATCGAGATCCCGGAAGTGCTGCGCCCGTATATGCGCGGCCTCGA
ATATATCGGCTAA

Protein sequence :
MLDPNLLRTEPDAVAEKLARRGFKLDVDKLRALEERRKVLQVQTENLQAERNSRSKSIGQAKARGEDIEPLRLEVNKLGE
QLDAAKSELETLLAEIRDIALAIPNIPHDDVPVGRDENDNVEVSRWGTPRQFDFEVRDHVTLGEMHGGLDFAAAVKLTGS
RFVVMKGQLARLHRALAQFMLDLHTEQHGYSENYVPYLVNQDTLYGTGQLPKFAGDLFHTRPLEEEADSSNYALIPTAEV
PLTNLVRDEIIDEDDLPIKMTAHTPCFRSEAGSYGRDTRGLIRMHQFDKVEMVQIVRPEDSMAALEEMTGHAEKVLQLLG
LPYRKVALCTGDMGFSACKTYDLEVWVPAQNTYREISSCSNVWDFQARRMQARCRSKSDKKTRLVHTLNGSGLAVGRTLV
ALMENYQQADGRIEIPEVLRPYMRGLEYIG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 3e-107 57