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Name : leuS (KPN_00674) Accession : YP_001334354.1 Strain : Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Genome accession: NC_009648 Putative virulence/resistance : Unknown Product : leucyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG0495 EC number : - Position : 760581 - 763163 bp Length : 2583 bp Strand : - Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl DNA sequence : ATGCAAGAGCAATACCGCCCGGAAGAGATAGAATCGAAAGTCCAGCTTCACTGGGACGAAAATCGTACATTTGAAGTAAC TGAAGACGAGAGCAAAGAGAAGTATTACTGCCTGTCGATGCTTCCTTATCCTTCTGGTCGACTACACATGGGTCACGTGC GTAACTACACCATCGGCGACGTGATTGCCCGCTACCAGCGCATGCTGGGCAAAAACGTCCTGCAGCCGATCGGCTGGGAT GCGTTCGGTCTGCCGGCAGAAGGGGCGGCGGTGAAAAACAACACCGCGCCAGCGCCGTGGACCTACGACAACATCGCCTA CATGAAAAACCAGCTCAAAATGCTGGGCTTCGGCTATGACTGGAGCCGCGAGCTGGCGACCTGCACCCCGGAATACTACC GCTGGGAGCAGAAGTTCTTCACCGAGCTGTACAAAAAAGGCCTGGTGTACAAAAAAACCTCCGCAGTGAACTGGTGCCCG AATGACCAGACCGTGCTGGCCAACGAACAGGTTATCGACGGCTGCTGCTGGCGCTGCGATACCAAGGTCGAGCGTAAAGA GATCCCGCAGTGGTTTATTAAAATCACCGCCTACGCCGATGAACTGCTGAACGATCTGGATAAGCTGGACCACTGGCCGG ACACCGTGAAGACCATGCAGCGCAACTGGATCGGCCGTTCGGAAGGGGTAGAAATCTCCTTTGACGTCAACGACTACGCT GACAAACTGACTGTCTACACCACCCGTCCGGACACCTTTATGGGTTGTACCTACCTGGCCGTCGCGGCGGGTCACCCGCT GGCGCAGCAGGCTGCGGCGAACAATCCGGCGCTGGCCACCTTTATCGACGAGTGCCGCAATACCAAAGTGGCCGAAGCCG ACATGGCGACGATGGAGAAAAAAGGCGTCGATACCGGCTTTAAAGCCATTCATCCGCTGACCGGTGAAGAAATTCCGGTC TGGGCGGCAAACTTTGTGCTGATGGAATACGGCACCGGCGCGGTAATGGCCGTTCCGGGTCACGACCAGCGCGACTACGA GTTCGCCAGCAAGTACGGTCTGAACATTAAGCCGGTTATCCTCGCTGCCGACGGCTCCGAGCCGGATCTCTCCGAGCAGG CGCTGACCGAGAAAGGCGTCCTGTTTAACTCCGGCGAGTTCAGCGGTCTTGATTATGAAGCGGGCTTCAACGCCATTGCC GACAAACTGGCTGCCATGGGCGTGGGCGAGCGTAAAGTTAACTACCGTCTGCGCGACTGGGGCGTATCCCGTCAGCGCTA CTGGGGCGCGCCGATCCCGATGGTGACCCTGGAAGATGGCACCGTGCTGCCGACCCCGGAAGATCAGCTGCCGGTGATCC TGCCGGAAGACGTGGTCATGGACGGCATCACCAGCCCGATCAAAGCCGATCCTGAATGGGCCAAGACCACCGTCAACGGC CAGCCGGCGCTGCGCGAAACCGACACCTTTGACACCTTTATGGAATCCTCCTGGTACTATGCGCGCTACACCTGCCCGCA GTATCAGGAAGGAATGCTGGATTCGAAAGCGGCCAACTACTGGCTGCCGGTAGATATCTACATCGGCGGTATCGAACACG CCATCATGCACCTGCTCTACTTCCGCTTCTTCCATAAGCTGATGCGCGACGCGGGCATGGTGAACTCCGATGAGCCGGCG AAACAGCTGCTGTGCCAGGGCATGGTGCTGGCTGACGCGTTCTACTATGTGGGCGAAAACGGCGAACGTAACTGGGTTTC CCCGGTTGACGCCATCGTTGAGCGCGACGAAAAAGGCCGCATCGTGAAGGCCAAAGACGCGGCGGGCCACGAGCTGGTGT ACACCGGCATGAGCAAGATGTCCAAGTCGAAAAACAACGGCATCGACCCGCAGGTGATGGTTGAGCGCTACGGCGCGGAT ACCGTGCGTCTGTTCATGATGTTTGCGTCCCCGGCGGATATGACCCTCGAGTGGCAGGAATCTGGCGTTGAAGGGGCGAA CCGCTTCCTGAAACGCGTCTGGAAACTGGTCTACGAGCACACCACTAAAGGAGAGGTTGCGGCACTGAACGTGGCGGCTC TGAGCGAAGATCAGAAAGCGCTGCGTCGCGATATCCACAAAACCATCGCCAAAGTGACCGATGACATCGGCCGTCGTCAG ACCTTCAACACCGCCATCGCGGCAATCATGGAGCTGATGAACAAGCTGGCGAAAGCGCCGCAGGAAGATGAGCAGGATCG TGCGCTGATGCAGGAAGCTCTGCTGGCGGTGGTGCGTATGCTCAACCCGTTCACTCCGCACGCCAGCTTCACCCTGTGGC GTGAGCTGAACGGCGAAGGCGATATCGACAACGCGCCGTGGCCGGTAGCGGATGAGAGCGCGATGGTGGAAGACAGCACC CTCGTCGTCGTCCAGGTCAATGGCAAAGTTCGTGGTAAAATTACCGTTGCGGTAGATGCAACTGAAGAGCAGGTTCGCGA GCGCGCCGGCCAGGAACATCTGGTGGCGAAATATCTCGACGGTAAAACCGTGCGTAAAGTGATTTACGTTCCGGGTAAAC TGCTCAATCTGGTCGTTGGCTAA Protein sequence : MQEQYRPEEIESKVQLHWDENRTFEVTEDESKEKYYCLSMLPYPSGRLHMGHVRNYTIGDVIARYQRMLGKNVLQPIGWD AFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSRELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCP NDQTVLANEQVIDGCCWRCDTKVERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEISFDVNDYA DKLTVYTTRPDTFMGCTYLAVAAGHPLAQQAAANNPALATFIDECRNTKVAEADMATMEKKGVDTGFKAIHPLTGEEIPV WAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPVILAADGSEPDLSEQALTEKGVLFNSGEFSGLDYEAGFNAIA DKLAAMGVGERKVNYRLRDWGVSRQRYWGAPIPMVTLEDGTVLPTPEDQLPVILPEDVVMDGITSPIKADPEWAKTTVNG QPALRETDTFDTFMESSWYYARYTCPQYQEGMLDSKAANYWLPVDIYIGGIEHAIMHLLYFRFFHKLMRDAGMVNSDEPA KQLLCQGMVLADAFYYVGENGERNWVSPVDAIVERDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGAD TVRLFMMFASPADMTLEWQESGVEGANRFLKRVWKLVYEHTTKGEVAALNVAALSEDQKALRRDIHKTIAKVTDDIGRRQ TFNTAIAAIMELMNKLAKAPQEDEQDRALMQEALLAVVRMLNPFTPHASFTLWRELNGEGDIDNAPWPVADESAMVEDST LVVVQVNGKVRGKITVAVDATEEQVRERAGQEHLVAKYLDGKTVRKVIYVPGKLLNLVVG |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| leuS | YP_281511.2 | leucyl-tRNA synthetase | Not tested | Not named | Protein | 3e-149 | 43 |
