Gene Information

Name : fepC (KPN_00606)
Accession : YP_001334286.1
Strain : Klebsiella pneumoniae subsp. pneumoniae MGH 78578
Genome accession: NC_009648
Putative virulence/resistance : Virulence
Product : iron-enterobactin transporter ATP-binding protein
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG1120
EC number : -
Position : 687049 - 687843 bp
Length : 795 bp
Strand : -
Note : with FepBDE is involved in the transport of ferric enterobactin

DNA sequence : 
ATGAGTGCTGTCCCCTCCCGTTTGCGCGGCGAGCAGTTAACCCTGGCCTACGGGAACAAGACCATCGCCGAGTCGCTGAA
CGTGACCATCCCTGACGGTCACTTCACCGCCATTATCGGCCCCAACGGCTGCGGCAAGTCGACGCTATTGCGCACCCTCA
GTCGCCTGATGACGCCCGCCAGCGGCCACGTCTGGCTCGACGGCGCGCAGATCCAGCAGTACGCCAGTAAAGAGGTTGCC
CGCCGCATCGGGCTGCTGGCGCAGAATGCCACCACCCCTGGCGATATCACGGTGCAGGAGCTGGTGGCCCGCGGGCGCTA
TCCGCACCAGCCGCTGTTTACCCGCTGGCGCAAAGAAGATGAAGAGGCGGTGAACAAGGCGATGCGGGCGACCGGGATCA
GCGATCTGGCGCTGCAGAGCGTCGACACGCTTTCCGGCGGCCAGCGGCAGCGGGCGTGGATTGCGATGGTGCTGGCCCAG
GAAACGGCGATTATGCTGCTGGATGAGCCGACCACCTGGCTGGACATCAGCCATCAGATCGACCTGCTGGAACTGTTGAG
CGAGCTGAATCGCGAGAAGGGCTATACCCTGGCGGCGGTGCTGCACGATCTTAACCAGGCCTGCCGCTACGCCACCCACC
TGATCGCCCTGCGCGACGGCAGGATCGTCGCCGAGGGGGCGCCGAAGGAGATCGTCACCGCCGATCTGATTGAACGGATT
TACGGTCTGCGCTGCACGATCATTGAAGATCCGGTGGCGCATACGCCGCTGGTGGTCCCGCTGGGCCGCCGGTAA

Protein sequence : 
MSAVPSRLRGEQLTLAYGNKTIAESLNVTIPDGHFTAIIGPNGCGKSTLLRTLSRLMTPASGHVWLDGAQIQQYASKEVA
RRIGLLAQNATTPGDITVQELVARGRYPHQPLFTRWRKEDEEAVNKAMRATGISDLALQSVDTLSGGQRQRAWIAMVLAQ
ETAIMLLDEPTTWLDISHQIDLLELLSELNREKGYTLAAVLHDLNQACRYATHLIALRDGRIVAEGAPKEIVTADLIERI
YGLRCTIIEDPVAHTPLVVPLGRR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
iusE YP_005143742.1 iron ABC transporter ATP-binding protein Virulence Not named Protein 7e-57 50
fecE AAL08451.1 ATP-binding protein FecE Virulence SRL Protein 2e-49 49
SPN23F_09560 YP_002510939.1 ferric siderophore ABC transporter ATP-binding protein Virulence PPI-1 Protein 8e-57 48
SP_1035 NP_345510.1 iron-compound ABC transporter ATP-binding protein Not tested PPI-1 Protein 8e-57 48
fagC YP_005682397.1 ATP binding cytoplasmic membrane protein Virulence PiCp 1 Protein 4e-56 48
fagC YP_005684488.1 ATP binding cytoplasmic membrane protein Not tested PiCp 1 Protein 4e-56 48
fagC YP_005680307.1 ATP binding cytoplasmic membrane protein Not tested PiCp 1 Protein 5e-56 48
fagC YP_003782430.1 ABC transporter ATP-binding protein Not tested PiCp 1 Protein 5e-56 48
ciuD YP_005681255.1 Iron ABC transporter ATP-binding protein Virulence PiCp 4 Protein 6e-46 41
ciuD YP_005683346.1 Iron ABC transporter ATP-binding protein Virulence PiCp 4 Protein 6e-46 41
ciuD YP_003783391.1 iron ABC transporter ATP-binding protein Virulence PiCp 4 Protein 6e-46 41
ciuD YP_005685432.1 Iron ABC transporter ATP-binding protein Virulence PiCp 4 Protein 6e-46 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
fepC YP_001334286.1 iron-enterobactin transporter ATP-binding protein BAC0164 Protein 1e-49 49

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
fepC YP_001334286.1 iron-enterobactin transporter ATP-binding protein VFG0925 Protein 1e-106 89
fepC YP_001334286.1 iron-enterobactin transporter ATP-binding protein VFG1042 Protein 1e-49 49