Gene Information

Name : cadA (KPN_00500)
Accession : YP_001334180.1
Strain : Klebsiella pneumoniae subsp. pneumoniae MGH 78578
Genome accession: NC_009648
Putative virulence/resistance : Virulence
Product : lysine decarboxylase 1
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG1982
EC number : -
Position : 548126 - 550273 bp
Length : 2148 bp
Strand : +
Note : -

DNA sequence :
ATGAACGTTATTGCAATCATGAATCACATGGGGGTTTACTTCAAAGAAGAACCCATCCGTGAACTGCATCGTGCTCTCGA
ACGCCTGGACTTCCGTATTGTCTACCCGAACGACCGTGACGACTTATTAAAACTTATTGAAAACAACTCTCGTCTGTGCG
GCGTGATCTTCGACTGGGATAAATACAATCTCGAACTGTGCGAAGAAATCAGCAAAATGAACGAGTACATGCCGCTGTAT
GCGTTCGCTAACACCTACTCCACTCTGGACGTTAGCCTGAACGATCTGCGCATGCAGGTTCGCTTCTTCGAATATGCGCT
GGGCGCTGCGGAAGATATCGCGAACAAAATCAAACAGAACACTGACGAATACATCGACACCATTCTGCCGCCGCTGACCA
AAGCGCTGTTCAAATATGTCCGTGAAGGTAAATATACCTTCTGTACCCCAGGCCACATGGGTGGTACCGCGTTCCAGAAA
AGCCCGGTAGGCAGCATCTTCTATGATTTCTTTGGCTCCAACACCATGAAATCCGATATCTCCATTTCGGTTTCTGAACT
GGGTTCCCTGCTGGACCACAGCGGCCCGCACAAAGAAGCGGAAGAGTATATCGCTCGCGTGTTTAACGCAGAACGCAGCT
ACATGGTGACCAACGGTACTTCTACCGCTAACAAAATCGTCGGCATGTACTCCGCGCCGGCCGGCAGCACCGTGCTGATT
GACCGTAACTGCCACAAATCGCTGACTCACCTGATGATGATGAGCGACATTACGCCGATCTATTTCCGTCCGACCCGTAA
CGCCTACGGTATCCTCGGCGGTATTCCGCAGAGCGAATTCCAGCACGCGACTATCGCCAAGCGTGTGAAAGAGACGCCGA
ACGCGACCTGGCCGGTACACGCGGTTATCACCAACTCGACTTACGATGGTCTGCTGTATAACACCGACTTCATCAAGAAA
ACCCTGGATGTGAAATCCATCCACTTTGACTCCGCATGGGTCCCTTACACCAACTTCTCGCCGATCTATGAAGGCAAATG
CGGGATGAGCGGCGGCCGCGTCGAAGGGAAAGTGATTTACGAAACCCAGTCCACGCACAAACTGCTGGCGGCGTTCTCCC
AGGCGTCGATGATCCACGTGAAAGGCGACGTAAACGAAGAGACCTTCAACGAAGCCTACATGATGCACACCACCACTTCC
CCGCACTACGGGATCGTGGCGTCCACCGAAACCGCGGCGGCGATGATGAAGGGGAACGCTGGTAAGCGTCTGATCGATGG
CTCTATTGAACGTTCCATCAAGTTCCGTAAAGAGATCAAACGTCTGAAAGGCGAGTCTGACGGCTGGTTCTTCGACGTCT
GGCAGCCGGAGCATATCGATGGTCCTGAATGCTGGCCGCTGCGTTCCGACAGCGCATGGCACGGTTTCAAAAACATCGAT
AACGAACACATGTACCTCGACCCGATCAAAGTCACGCTGCTGACGCCGGGGATGAAGAAAGACGGCACCATGGATGACTT
CGGTATTCCGGCAAGCATCGTGGCGAAATATCTCGACGAACACGGCATCGTGGTAGAGAAAACCGGTCCGTACAACCTGC
TGTTCCTGTTCAGTATCGGTATCGATAAGACTAAAGCGCTGAGCCTGCTGCGTGCGCTGACCGACTTCAAACGCGCGTTC
GACCTGAACCTGCGGGTGAAAAACATGCTGCCGTCGCTGTACCGTGAAGATCCTGAATTCTATGAAAACATGCGTATTCA
GGACCTCGCGCAGAACATTCACAAACTGATTGAGCATCACAACCTGCCGGATCTGATGTTCCGCGCGTTTGAAGTGCTGC
CATCGATGGTGATGACCCCGTATGCCGCGTTCCAGAAAGAGCTGCACGGTCAGACGGAAGAAGTGTATCTCGAAGAGATG
GTCGGCCGCGTCAACGCCAACATGATCCTGCCGTATCCTCCGGGAGTGCCGCTGGTGATGCCGGGTGAGATGATCACCGA
AGAGAGCCGTCCGGTGCTGGAGTTCCTGCAGATGCTGTGCGAAATCGGCGCCCACTATCCAGGCTTCGAAACCGATATCC
ACGGCGCCTATCGTCAGGCGGATGGTCGTTACACCGTTAAAGTGCTGAAAGAAGAGAATAACAAGTAA

Protein sequence :
MNVIAIMNHMGVYFKEEPIRELHRALERLDFRIVYPNDRDDLLKLIENNSRLCGVIFDWDKYNLELCEEISKMNEYMPLY
AFANTYSTLDVSLNDLRMQVRFFEYALGAAEDIANKIKQNTDEYIDTILPPLTKALFKYVREGKYTFCTPGHMGGTAFQK
SPVGSIFYDFFGSNTMKSDISISVSELGSLLDHSGPHKEAEEYIARVFNAERSYMVTNGTSTANKIVGMYSAPAGSTVLI
DRNCHKSLTHLMMMSDITPIYFRPTRNAYGILGGIPQSEFQHATIAKRVKETPNATWPVHAVITNSTYDGLLYNTDFIKK
TLDVKSIHFDSAWVPYTNFSPIYEGKCGMSGGRVEGKVIYETQSTHKLLAAFSQASMIHVKGDVNEETFNEAYMMHTTTS
PHYGIVASTETAAAMMKGNAGKRLIDGSIERSIKFRKEIKRLKGESDGWFFDVWQPEHIDGPECWPLRSDSAWHGFKNID
NEHMYLDPIKVTLLTPGMKKDGTMDDFGIPASIVAKYLDEHGIVVEKTGPYNLLFLFSIGIDKTKALSLLRALTDFKRAF
DLNLRVKNMLPSLYREDPEFYENMRIQDLAQNIHKLIEHHNLPDLMFRAFEVLPSMVMTPYAAFQKELHGQTEEVYLEEM
VGRVNANMILPYPPGVPLVMPGEMITEESRPVLEFLQMLCEIGAHYPGFETDIHGAYRQADGRYTVKVLKEENNK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cadA NP_756988.1 lysine decarboxylase, inducible Not tested PAI II CFT073 Protein 0.0 95
unnamed CAD66195.1 putative cadaverin decarboxylase Virulence PAI III 536 Protein 0.0 67

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
cadA YP_001334180.1 lysine decarboxylase 1 VFG1670 Protein 0.0 67