Gene Information

Name : pepA (KPN_04665)
Accession : YP_001338283.1
Strain : Klebsiella pneumoniae subsp. pneumoniae MGH 78578
Genome accession: NC_009648
Putative virulence/resistance : Unknown
Product : leucyl aminopeptidase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0260
EC number : -
Position : 5098256 - 5099767 bp
Length : 1512 bp
Strand : -
Note : catalyzes the removal of N-terminal amino acids preferably leucine from various peptides

DNA sequence :
ATGGAGTTCAGTGTAAAAAGCGGTAGCCCGGAGAAGCAGCGGAGCGCCTGTATCGTGGTCGGCGTCTTTGAACCACGTCG
CCTCTCCCCCATCGCCGAACAACTCGATAAAATCAGCGACGGCTACATCAGCGCCCTGCTGCGTCGCGGCGAGCTGGAAG
GCAAACCTGGCCAGACGTTATTGCTGCACCATGTGCCAAACATTCTGTCTGAGCGCATTCTGCTGATTGGCTGCGGCAAA
GAGCGCGAGCTGGATGAGCGTCAGTATAAGCAGGTCATCCAGAAAACCATCAATACCCTGAATGATACCGGCTCAATGGA
AGCCGTCTGCTTCCTGACCGAGCTGCACGTCAAAGGCCGTAACAACTACTGGAAAGTTCGCCAGGCGGTTGAAACCGCCA
AAGAGACGCTGTACAGCTTCGACCAGCTGAAGACCAACAAAAGCGAGCCGCGTCGCCCGCTGCGTAAAATGGTCTTTAAC
GTGCCGACCCGTCGCGAGCTGACCAGCGGCGAACGCGCCATTCAGCATGGCCTGGCGATTGCCGCCGGCATCAAAGCGGC
GAAAGATCTTGGCAATATGCCGCCGAACATCTGTAACGCCGCCTATCTGGCTTCCCAGGCGCGTCAGCTGGCCGATACCT
ACAGCAAAAACGTCATCACCCGGGTGATCGGCGAACAGCAGATGCGCGAGCTGGGGATGAACGCCTACCTCGCCGTCGGC
AATGGGTCGCAGAACGAGTCGCTGATGTCGGTCATCGAATATAAAGGTAACCCGGCTGAGGACGCGCGCCCTATCGTGCT
GGTCGGTAAAGGCCTGACCTTCGACTCCGGCGGTATCTCCATCAAGCCTGCCGAAGGCATGGACGAGATGAAGTACGACA
TGTGCGGCGCGGCGGCGGTGTACGGCGTGATGCGGATGGTTGCCGAACTGCAGCTGCCGCTGAACGTCATCGGCGTGCTG
GCGGGCTGTGAAAACATGCCTGGCGGCCGCGCCTATCGTCCGGGTGACGTCCTGACCACTATGTCCGGCCAGACGGTGGA
AGTGCTGAACACCGACGCCGAAGGCCGCCTGGTGCTGTGCGACGTCCTGACCTACGTTGAGCGCTTCGAGCCGGAAGCGG
TTATCGACGTGGCGACGCTGACCGGGGCCTGCGTGATTGCCCTCGGCCATCACATCACCGGCCTGATGTCGAACCATAAC
CCGCTGGCCCATGAGCTAATCGGCGCCTCCGAACTGGCGGGCGACCGCGCATGGCGTTTGCCGCTGGCCGACGAGTTCCA
GGATCAGCTGGAGTCCAATTTTGCCGATATGGCGAACATTGGCGGCCGTCCTGGCGGCGCGATCACCGCCGGCTGTTTCC
TGTCGCGCTTCACCCGCAAGTACAACTGGGCGCACCTCGACATCGCCGGTACTGCCTGGCGTTCCGGTAAGGCCAAAGGC
GCGACCGGTCGTCCGGTGGCGCTGCTGTCGCAGTTCCTGCTCAATCGTGCGGGTTTTAACGGCGAAGAGTGA

Protein sequence :
MEFSVKSGSPEKQRSACIVVGVFEPRRLSPIAEQLDKISDGYISALLRRGELEGKPGQTLLLHHVPNILSERILLIGCGK
ERELDERQYKQVIQKTINTLNDTGSMEAVCFLTELHVKGRNNYWKVRQAVETAKETLYSFDQLKTNKSEPRRPLRKMVFN
VPTRRELTSGERAIQHGLAIAAGIKAAKDLGNMPPNICNAAYLASQARQLADTYSKNVITRVIGEQQMRELGMNAYLAVG
NGSQNESLMSVIEYKGNPAEDARPIVLVGKGLTFDSGGISIKPAEGMDEMKYDMCGAAAVYGVMRMVAELQLPLNVIGVL
AGCENMPGGRAYRPGDVLTTMSGQTVEVLNTDAEGRLVLCDVLTYVERFEPEAVIDVATLTGACVIALGHHITGLMSNHN
PLAHELIGASELAGDRAWRLPLADEFQDQLESNFADMANIGGRPGGAITAGCFLSRFTRKYNWAHLDIAGTAWRSGKAKG
ATGRPVALLSQFLLNRAGFNGEE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00295 YP_008207760.1 Leucyl aminopeptidase Not tested AbaR25 Protein 1e-88 54
BJAB0868_00299 YP_008211625.1 Leucyl aminopeptidase Not tested AbaR26 Protein 1e-88 54