Gene Information

Name : purA (KPN_04576)
Accession : YP_001338194.1
Strain : Klebsiella pneumoniae subsp. pneumoniae MGH 78578
Genome accession: NC_009648
Putative virulence/resistance : Unknown
Product : adenylosuccinate synthetase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0104
EC number : -
Position : 5005899 - 5007197 bp
Length : 1299 bp
Strand : +
Note : catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis

DNA sequence :
ATGGGTAACAACGTCGTCGTACTGGGCACCCAATGGGGTGACGAAGGTAAAGGGAAGATCGTCGATCTCCTGACTGAACG
GGCTAAATATGTTGTGCGCTACCAGGGTGGTCACAACGCCGGCCATACTCTCGTAATCAACGGTGAAAAAACCGTTCTCC
ATCTTATTCCATCAGGCATTCTGCGTGAAAACGTCACCAGCATCATCGGTAACGGCGTCGTGCTGTCTCCGGCCGCGCTG
ATGAAAGAGATGAAGGGCCTGGAAGACCGTGGTATCCCGGTTCGCGAGCGTCTGCTGCTCTCTGAAGCCTGCCCGCTTAT
CCTTGACTATCACGTGGCGCTTGACGTGGCGCGTGAAAAAGCGCGTGGCGCGAAAGCGATCGGCACTACCGGTCGCGGCA
TTGGCCCGGCTTACGAAGATAAAGTCGCTCGTCGCGGTCTGCGCGTTGGCGATCTGTTCGATAAAGCAACCTTCGCCGAT
AAACTGAAAGAAGTGATGGAATATCACAACTTCCAGTTGGTGAACTTCTACAAAGCAGAAGCGGTTGACTACCAGAAAGT
GCTGGACGATGTGATGGCGATTGCCGACATCCTGACCAGCATGGTGGTGGACGTATCCGACCTGCTGGATCAGGCGCGTC
AGCGCGGCGACTTCGTGATGTTCGAAGGCGCGCAGGGTACGCTGCTGGATATCGACCACGGTACCTACCCGTACGTTACG
TCCTCTAACACCACCGCAGGTGGCGTGGCGACCGGCTCCGGCCTGGGCCCGCGTTATGTGGATTACGTACTGGGCATCAT
TAAAGCGTACTCGACTCGCGTCGGTGCAGGTCCGTTCCCGACCGAGCTGTTTGATGAAACTGGCGAGTTCCTCTGCAAGC
AGGGTAACGAATTTGGCGCCACCACCGGCCGCCGTCGTCGTACCGGCTGGCTGGACGCGGTCGCAGTCCGTCGCGCGGTG
CAGATTAACTCCCTGTCCGGCTTCTGCCTGACTAAACTGGACGTCCTCGACGGCCTGAAAGAAGTGAAAATCTGCGTTGG
CTACCGTATGCCGGATGGCCGCGAAGTGACCACCACTCCGCTGGCTGCCGATAACTGGGAAGGTATCGAGCCTATCTACG
AAACCATGCCGGGCTGGTCCGAAACCACCTTCGGCGTGAAAGAGCGCAGCGGCCTGCCGCAGGCAGCCCTGAACTACATC
CAGCGTATTGAAGAGCTGACCGGCGTGCCGGTGGATATCATCTCTACCGGTCCAGACCGTACCGAGACTATGATTCTGCG
CGATCCGTTCGACGCGTAA

Protein sequence :
MGNNVVVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRENVTSIIGNGVVLSPAAL
MKEMKGLEDRGIPVRERLLLSEACPLILDYHVALDVAREKARGAKAIGTTGRGIGPAYEDKVARRGLRVGDLFDKATFAD
KLKEVMEYHNFQLVNFYKAEAVDYQKVLDDVMAIADILTSMVVDVSDLLDQARQRGDFVMFEGAQGTLLDIDHGTYPYVT
SSNTTAGGVATGSGLGPRYVDYVLGIIKAYSTRVGAGPFPTELFDETGEFLCKQGNEFGATTGRRRRTGWLDAVAVRRAV
QINSLSGFCLTKLDVLDGLKEVKICVGYRMPDGREVTTTPLAADNWEGIEPIYETMPGWSETTFGVKERSGLPQAALNYI
QRIEELTGVPVDIISTGPDRTETMILRDPFDA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
purA YP_281500.1 adenylosuccinate synthetase Not tested Not named Protein 7e-88 48