Gene Information

Name : actP (KPN_04476)
Accession : YP_001338098.1
Strain : Klebsiella pneumoniae subsp. pneumoniae MGH 78578
Genome accession: NC_009648
Putative virulence/resistance : Resistance
Product : acetate permease
Function : -
COG functional category : R : General function prediction only
COG ID : COG4147
EC number : -
Position : 4898779 - 4900434 bp
Length : 1656 bp
Strand : -
Note : member of the sodium:solute symporter family; cotranscribed with the acs gene which encodes acetyl coenzyme A synthase; mutations affect acetate uptake

DNA sequence :
ATGATCAAGAGAGTCCTGACGGCGCTCGCCGCCACGCTGCTGCCCCTCGGCGCTCACGCCGCAGACGCTATTACCGGCGC
GGTACAGCGCCAGCCGACCAACTGGCAGGCGATTGTCATGTTCCTGATTTTCGTCGCCCTAACGCTGTACATCACCTACT
GGGCCTCAAAACGGGTGCGTTCGCGCAGCGATTACTACACCGCCGGCGGCAATATTACCGGCTTCCAGAACGGGCTGGCG
ATTGCCGGCGACTTTATGTCAGCGGCGTCGTTCCTCGGTATCTCCGCGCTGGTGTATACCTCCGGCTACGATGGGCTGAT
CTACTCGCTGGGCTTTCTCGTCGGCTGGCCGATTATCCTGTTTCTAATTGCTGAACGTCTGCGCAATCTTGGCCGCTATA
CTTTTGCCGATGTCGCCTCTTACCGCCTGAAGCAGGGGCCGATCCGCACCCTCTCCGCCTGCGGTTCGCTGGTGGTGGTG
GCCCTGTATCTGATTGCCCAGATGGTGGGCGCCGGCAAGCTAATCCAGCTGCTGTTCGGCCTTAATTACCATGTCGCCGT
AGTGCTGGTTGGCGTGCTGATGGTGCTCTATGTCCTGTTCGGCGGCATGCTGGCGACTACCTGGGTGCAGATTATTAAAG
CGGTTCTGCTGCTGTGCGGCGCCAGCTTTATGGCCTTTATGGTCATGAAGCACGTCGGCTTCAGCTTCAATAACCTGTTT
ACCGAGGCGATGGCGGTCCACCCGAAAGGGGCGGCGATTATGAGTCCCGGCGGACTGGTGAAAGATCCGATATCCGCGCT
CTCTCTGGGTCTGGGTCTGATGTTCGGTACCGCTGGCCTGCCGCATATTCTGATGCGCTTCTTTACCGTGAGCGACGCCA
AAGAAGCGCGTAAAAGCGTCTTCTACGCCACCGGTTTTATGGGCTATTTCTATATCCTGACCTTTATCATCGGCTTCGGC
GCCATCATGCTGGTCGGCGCGAACCCGGCGTTTAAAGACGCGGCCGGACAGCTTATCGGCGGCAATAACATGGCGGCGGT
GCACCTGGCGGATGCGGTTGGCGGCAACCTGTTCCTCGGCTTTATCTCTGCGGTAGCCTTCGCCACTATCCTGGCGGTGG
TGGCGGGCCTGACCCTCGCCGGCGCGTCAGCGGTGTCGCACGACCTGTACGCCAACGTCTTCCGCAAGGGCGCGACCGAG
CGTCAGGAGCTGAAGGTCTCCAAGATCACCGTGCTGATCCTTGGGGTGGTGGCCATTCTGCTGGGTATTCTGTTTGAAAA
TCAGAATATTGCTTTCATGGTCGGCCTGGCCTTCTCCATCGCCGCCAGCTGTAACTTCCCGATTATACTGCTGTCGATGT
ACTGGTCGAAGCTGACCACCCGCGGCGCGATGGTCGGAGGCTGGCTGGGCCTGCTGACTGCGGTCATTCTGATGATCCTC
GGCCCCACCATTTGGGTGCAGATCCTCGGCCATGAGAAAGCGCTGTTCCCGTATGAATATCCGGCGCTGTTCTCCATTGC
CATCGCGTTCATTGGCATCTGGGTCTTCTCCGCCACCGATAACTCACCGGAAGGGATGCGCGAGCGCGAGCAGTTCCGCG
CCCAGTTTATCCGTTCACAAACCGGGATCGGTATCGAACGCGGCCAGGCGCATTAA

Protein sequence :
MIKRVLTALAATLLPLGAHAADAITGAVQRQPTNWQAIVMFLIFVALTLYITYWASKRVRSRSDYYTAGGNITGFQNGLA
IAGDFMSAASFLGISALVYTSGYDGLIYSLGFLVGWPIILFLIAERLRNLGRYTFADVASYRLKQGPIRTLSACGSLVVV
ALYLIAQMVGAGKLIQLLFGLNYHVAVVLVGVLMVLYVLFGGMLATTWVQIIKAVLLLCGASFMAFMVMKHVGFSFNNLF
TEAMAVHPKGAAIMSPGGLVKDPISALSLGLGLMFGTAGLPHILMRFFTVSDAKEARKSVFYATGFMGYFYILTFIIGFG
AIMLVGANPAFKDAAGQLIGGNNMAAVHLADAVGGNLFLGFISAVAFATILAVVAGLTLAGASAVSHDLYANVFRKGATE
RQELKVSKITVLILGVVAILLGILFENQNIAFMVGLAFSIAASCNFPIILLSMYWSKLTTRGAMVGGWLGLLTAVILMIL
GPTIWVQILGHEKALFPYEYPALFSIAIAFIGIWVFSATDNSPEGMREREQFRAQFIRSQTGIGIERGQAH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed AAK01502.1 putative amino acid transport protein Not tested PAGI-1 Protein 3e-124 59
cur_1523 YP_001800917.1 transporter Not tested Not named Protein 5e-69 44

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
actP YP_001338098.1 acetate permease BAC0564 Protein 0.0 92
actP YP_001338098.1 acetate permease BAC0570 Protein 1e-136 65