Gene Information

Name : dnaB (KPN_04439)
Accession : YP_001338061.1
Strain : Klebsiella pneumoniae subsp. pneumoniae MGH 78578
Genome accession: NC_009648
Putative virulence/resistance : Unknown
Product : replicative DNA helicase
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0305
EC number : -
Position : 4855739 - 4857154 bp
Length : 1416 bp
Strand : +
Note : unwinds double stranded DNA

DNA sequence :
ATGGCAGGAAATAAACCCTTCAACAAACCACAGACAGAAACCCGCGAACGCGATCCGCAGCTCGCCGGGCTGAAAGTCCC
GCCGCACTCGATTGAAGCGGAGCAGTCGGTGTTGGGCGGTTTAATGCTGGACAACGAGCGCTGGGACGACGTCGCCGAAC
GCGTCGTTGCCGACGACTTTTATACCCGTCCGCACCGTCATATTTTTACCGAGATGGCGCGCCTGCAGGAGTCCGGCAGC
CCGATTGACCTGATTACGCTCGCCGAGTCGCTGGAGCGTCAGGGGCAGCTGGACAGCGTGGGCGGCTTCGCCTATCTGGC
CGAACTGTCCAAAAACACGCCCAGCGCGGCTAACATCAGCGCCTATGCCGACATCGTGCGCGAACGCGCGGTGGTGCGCG
AAATGATTTCGGTGGCCAACGAGATCGCCGAAGCCGGCTTCGACCCGCAGGGGCGAACCAGCGAAGATCTGCTCGACCTC
GCCGAATCCCGGGTTTTCAAAATCGCCGAAAGCCGGGCCAACAAAGACGAAGGGCCGAAGAACATCGCCGATGTCCTCGA
TGCCACCGTCGCCCGTATCGAACAGCTGTTCCAGCAGCCCCATGACGGCGTCACCGGGGTCAATACCGGCTACGACGACC
TCAACAAAAAGACCGCCGGCCTGCAGCCGTCGGATCTGATTATCGTCGCCGCCCGTCCATCGATGGGTAAAACGACCTTC
GCGATGAACCTCGTGGAAAACGCGGCGATGCTGCAGGACAAACCGGTATTAATCTTCAGTCTCGAGATGCCCTCGGAACA
GATCATGATGCGTTCTCTGGCCTCGCTGTCGCGCGTCGATCAGACCCGCATTCGTACCGGTCAACTGGACGACGAAGACT
GGGCGCGGATCTCCGGCACCATGGGCATCCTGCTGGAAAAGCGCAATATCTATATCGATGACTCCTCCGGCCTGACGCCG
ACGGAGGTGCGCTCCCGCGCGCGTCGTATCGCCCGCGAGCACGGCGGTATCGGACTGATTATGATCGACTACCTGCAGCT
GATGCGCGTGCCGTCGCTCTCCGACAACCGTACCCTTGAGATTGCCGAAATCTCCCGCTCGCTGAAGGCGCTGGCGAAAG
AGCTGCAGGTGCCGGTGGTGGCGCTGTCGCAGCTTAACCGCTCGCTGGAGCAGCGCGCCGATAAGCGCCCGGTCAACTCC
GACCTGCGTGAGTCCGGCTCTATCGAACAGGATGCCGACTTAATCATGTTCATTTACCGTGATGAGGTCTATCACGAGAA
CAGCGATCTTAAAGGCATCGCGGAAATTATCATTGGTAAACAACGTAACGGTCCGATCGGCACCGTGCGACTGACCTTTA
ACGGCCAGTGGTCGCGTTTCGATAATTATGCCGGTCCTCAGTATGATGATGAGTAA

Protein sequence :
MAGNKPFNKPQTETRERDPQLAGLKVPPHSIEAEQSVLGGLMLDNERWDDVAERVVADDFYTRPHRHIFTEMARLQESGS
PIDLITLAESLERQGQLDSVGGFAYLAELSKNTPSAANISAYADIVRERAVVREMISVANEIAEAGFDPQGRTSEDLLDL
AESRVFKIAESRANKDEGPKNIADVLDATVARIEQLFQQPHDGVTGVNTGYDDLNKKTAGLQPSDLIIVAARPSMGKTTF
AMNLVENAAMLQDKPVLIFSLEMPSEQIMMRSLASLSRVDQTRIRTGQLDDEDWARISGTMGILLEKRNIYIDDSSGLTP
TEVRSRARRIAREHGGIGLIMIDYLQLMRVPSLSDNRTLEIAEISRSLKALAKELQVPVVALSQLNRSLEQRADKRPVNS
DLRESGSIEQDADLIMFIYRDEVYHENSDLKGIAEIIIGKQRNGPIGTVRLTFNGQWSRFDNYAGPQYDDE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
PMI2640 YP_002152342.1 DNA helicase Not tested Not named Protein 1e-105 55
dnaB2 YP_001402701.1 replicative DNA helicase Not tested YAPI Protein 2e-106 54
api2 CAF28476.1 putative DNA binding protein with DNA-dependent ATPase activity Not tested YAPI Protein 5e-107 54
dnaB2 YP_001007676.1 putative DNA helicase Not tested YAPI Protein 1e-106 54
dnaB CAI36044.1 replicative DNA helicase DnaB Not tested PPHGI-1 Protein 2e-87 50
unnamed ABR13456.1 replicative DNA helicase Not tested PAGI-5 Protein 3e-100 50
t4227 NP_807829.1 DNA helicase Not tested SPI-7 Protein 1e-91 50
STY4522 NP_458617.1 DNA helicase Not tested SPI-7 Protein 1e-91 50
dnaB1 YP_005176258.1 replicative DNA helicase Not tested ICEPmu1 Protein 1e-82 45