Gene Information

Name : hemC (KPN_04304)
Accession : YP_001337939.1
Strain : Klebsiella pneumoniae subsp. pneumoniae MGH 78578
Genome accession: NC_009648
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : -
Position : 4710846 - 4711787 bp
Length : 942 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGTTAGACAAAGTTTTGAAAATTGCCACACGGCAAAGCCCGCTTGCGCTATGGCAGGCGCAGTATGTTAAAGCGCGCCT
GGAACAAGCGCATCCCGGACTGAAGGTCGAGCTGGTGCCGATGGTCACGCGCGGGGATGTCATCCTTGATACTCCGCTGG
CAAAGGTGGGGGGAAAAGGCTTATTTGTGAAAGAGTTAGAGCTCGCCATGCTCGAAGGGCGCGCCGATATCGCCGTCCAT
TCGATGAAAGATGTGCCGGTGGAATTCCCGGAGGGCCTGGGGCTGGTGACTATCTGCGAGCGCGACGATCCGCGCGACGC
GTTTGTCTCCAATCGCTATGCCTCGATTGACGAACTGCCGGCCGGCAGCGTCGTTGGCACGTCAAGTTTACGCCGTCAGT
GCCAGCTGGCCGCCACCCGTCCGGACCTGGCGATCCGCTCTCTGCGCGGTAACGTCGGTACCCGGCTGAGTAAGCTGGAT
AACGGCGAGTACGACGCCATCATCCTCGCCGCCGCCGGCCTGAAGCGCCTGCAGCTGGAAGCGCGTATTCGCCAGCCGCT
GTCGCCTGAGCAATCTCTGCCGGCGGTCGGCCAGGGCGCGGTCGGCATCGAATGCCGTCTTGATGATGCATGGACCCGGG
GGCTGTTAGCGCCTCTCAACCATACGGAAACGGCGGTGCGCGTGCGCGCCGAGCGGGCGATGAACACCCGCCTCGAAGGC
GGCTGCCAGGTGCCGATCGGCAGCTATGCGGAACTGAAGGACGGGGAACTGTGGCTGCGGGCGCTGGTTGGCGCTCCGGA
TGGTTCACAGCTGGTGCGCGGCGAACGACGCGGGCCAGCGGAACAAGCGGAAGCCCTCGGCATCTCGCTGGCGGAAGAGC
TTCTGGATAATGGCGCCCGCGAGATTCTCGCGGCGGTTTATGATGGAGAAGCCCCGCGATGA

Protein sequence :
MLDKVLKIATRQSPLALWQAQYVKARLEQAHPGLKVELVPMVTRGDVILDTPLAKVGGKGLFVKELELAMLEGRADIAVH
SMKDVPVEFPEGLGLVTICERDDPRDAFVSNRYASIDELPAGSVVGTSSLRRQCQLAATRPDLAIRSLRGNVGTRLSKLD
NGEYDAIILAAAGLKRLQLEARIRQPLSPEQSLPAVGQGAVGIECRLDDAWTRGLLAPLNHTETAVRVRAERAMNTRLEG
GCQVPIGSYAELKDGELWLRALVGAPDGSQLVRGERRGPAEQAEALGISLAEELLDNGAREILAAVYDGEAPR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 2e-88 64
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 2e-88 64