Gene Information

Name : KPN_04195 (KPN_04195)
Accession : YP_001337841.1
Strain : Klebsiella pneumoniae subsp. pneumoniae MGH 78578
Genome accession: NC_009648
Putative virulence/resistance : Virulence
Product : PTS system ascorbate-specific transporter subunit IIC
Function : -
COG functional category : S : Function unknown
COG ID : COG3037
EC number : -
Position : 4595028 - 4596395 bp
Length : 1368 bp
Strand : +
Note : membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr

DNA sequence :
ATGAATAGCTTCGTGGCGTTTATCGTTAAGGATTTACTCGGCCAGGCATCCATTCTTATTGCTTTTATTGCCATGCTTGG
CCTGATCCTGCAAAAGAAATCGCCAGGCAAAACCGCGGAAGGGACATTTAAAACGCTGCTCGGTTTCTTAATTATGATGG
CCGGGATAAACATCATTGTCGCCACGCTGACCTTCCTGAATGATATCTTCACCCAGGGATTTGGCATGAAAGGCTATATT
ACCGATGTGGCCGCCATCGCCGGGTTAGCGAATCGGGAATTAGGTTCGGAGGTGGCGCTGACGCTGCTGGTGATCTTTGC
CGTCAATATTATTAACGCCCGGCTGACGCCGCTGAAATATATTTTTCTGACCGGCCAGGCGCTGCTGTGGATGGCGACGA
TCGGCGCCGTGATTGGCTATAAGTCCGGGCTCACCGGCGTACCGCTGATTTTAACCGGGGGCATCTTCGGCGGCGTGATG
GCGGTGTTAATGCCGGCCCTGGCGCAGCCGGTGGTCAGGCGCATTACCGGGTCTGACGATGTGGCCCTGGGGCACTTCTG
TACTATCGGCTATCTGGTGCAGGCTGCGGTCGCTAAAGTTGTCGGAAAAGGCTCTCGCTCCACGGAAGATCTCGAACTGC
CTGATAACTTTAAGTTTCTGCAGGATACCTATCTGGCCATGGCGGTGGTGATGGTGCCGATGTATCTCATCCCGGCTATC
GCGGCGGGGCCTCAGTACATCGCGCAGTTCTCCGGCGGCATTAATTACCTGATGTATGCCTTCATGCAGTCCATTCAGTT
TGTCGCCGGGGTCTTTGTCCTCTATAGCGGCGTGCGTTTATTACTCAATGAGCTGGTGCCGGCTTTTCGCGGTATCGCGA
TGCGTATTGTCCCGGATGCAAAGCCCGCTCTCGATTGCCCGGTGCTATTTCCCTATGCGCCGAATGCGGTGATTGTTGGA
TTTCTGGCAACGACTGTCGGCTCGATTATCGGCATGCTGGTTTTCCCGATGTTCGGCCTGGCGATGATTCTCCCCGGGCT
GTTAACCAACTTTTTCGCCGGCGGTACGGCAGGGGTATTTGGCAATGCGCTGGGCGGACGTCGCGGGGCGATGATCGGCG
GGGTGATTCACGGCCTGTTTATCACATTTCTGCCGGCCATTCTGGTACCCATGCTGGAGAGCTACGGCTTTACGGGCGTC
ACCTTCAGCGATTCAGACGTCATCAGCTCCGGTCTGGTATTAGGCCACGCCTTCCAGAATAACTGGCTCTTTGTCGCCTT
GTTTATTGTGTTTGTCGCCGCACTGGCATGGTTTGTAAACGGTAAATCCGCTAAGCCGAAAGGGGAAAGTGTTCATGAGT
CTGTATAA

Protein sequence :
MNSFVAFIVKDLLGQASILIAFIAMLGLILQKKSPGKTAEGTFKTLLGFLIMMAGINIIVATLTFLNDIFTQGFGMKGYI
TDVAAIAGLANRELGSEVALTLLVIFAVNIINARLTPLKYIFLTGQALLWMATIGAVIGYKSGLTGVPLILTGGIFGGVM
AVLMPALAQPVVRRITGSDDVALGHFCTIGYLVQAAVAKVVGKGSRSTEDLELPDNFKFLQDTYLAMAVVMVPMYLIPAI
AAGPQYIAQFSGGINYLMYAFMQSIQFVAGVFVLYSGVRLLLNELVPAFRGIAMRIVPDAKPALDCPVLFPYAPNAVIVG
FLATTVGSIIGMLVFPMFGLAMILPGLLTNFFAGGTAGVFGNALGGRRGAMIGGVIHGLFITFLPAILVPMLESYGFTGV
TFSDSDVISSGLVLGHAFQNNWLFVALFIVFVAALAWFVNGKSAKPKGESVHESV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAC39291.1 hypothetical protein Not tested LPA Protein 5e-83 44
vpeC ADD91725.1 putative PTS system-specific IIC component VpeC Virulence PAI-I AL862 Protein 5e-83 44
ORF8 AAK27335.1 unknown Not tested PAI-I AL862 Protein 5e-83 44